Ischemic Stroke Clinical Trials in Philadelphia, Pennsylvania

6 studies are recruiting for ischemic stroke in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

   The overall goal of the DISCOVERY study is to better understand what factors contribute to changes in cognitive (i.e., thinking and memory) abilities in patients who experienced a stroke. The purpose of the study is to help doctors identify patients at risk for dementia (decline in memory, thinking…

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   31 in total

   Run by

   Massachusetts General Hospital

   See if you can join NCT04916210 on ClinicalTrials.gov

2. Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

   This is a Phase 2/3 study evaluating the safety and efficacy of DM199 (rinvecalinase alfa) in treating participants with moderate stroke severity, who present within 24 hours of Acute Ischemic Stroke (AIS) onset due to small and medium vessel occlusions. This study focuses on participants with limi…

   Stage

   Phase 2

   Ages

   18 to 90

   Site

   The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   86 in total

   Run by

   DiaMedica Therapeutics Inc

   See if you can join NCT05065216 on ClinicalTrials.gov

3. Strategy for Improving Stroke Treatment Response

   SISTER is a Phase-II, prospective, randomized, placebo-controlled, blinded, dose finding trial that aims to determine the safety and preliminary efficacy of TS23, a monoclonal antibody against the alpha-2 antiplasmin (a2-AP), in acute ischemic stroke.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Temple University Hospital, Philadelphia, Pennsylvania

   Locations

   52 in total

   Run by

   Translational Sciences, Inc.

   See if you can join NCT05948566 on ClinicalTrials.gov

4. CTSN Embolic Protection Trial

   This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.

   Stage

   Not phased

   Ages

   60 and older

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   28 in total

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT06027788 on ClinicalTrials.gov

5. Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

   The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients with subacute stroke.

   Stage

   Not phased

   Ages

   18 to 90

   Site

   Penn Medicine Rehabilitation, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT04897334 on ClinicalTrials.gov

6. StrokeNet Thrombectomy Endovascular Platform

   STEP is a Randomized, Multifactorial, Adaptive Platform trial that seeks to optimize the care of patients with acute ischemic stroke (AIS) due to large (LVO) or medium vessel occlusions (MVO).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

   Locations

   41 in total

   Run by

   Medical University of South Carolina

   See if you can join NCT06289985 on ClinicalTrials.gov