Huntington Disease Clinical Trials in Boston, Massachusetts

3 studies are recruiting for huntington disease in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

    The goal of this clinical trial is to test if the drug SKY-0515, an oral medication, can lower harmful proteins linked to Huntington's Disease (HD) and improve the symptoms of participants with HD. This study includes men and women aged 25 and older who have HD confirmed by genetic testing and meet…

    Stage
    Phase 2
    Ages
    25 and older
    Site
    Beth Israel Deaconess Medical Center, Boston, Massachusetts
    Locations
    31 in total
    Run by
    Skyhawk Therapeutics, Inc.

    See if you can join NCT07378644 on ClinicalTrials.gov

  2. A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

    The purpose is to assess safety and tolerability of votoplam and to determine whether votoplam slows disease progression in patients with early symptomatic Huntington's disease (HD) compared to the control arm. HTT227 - current compound code (former code is PTC518 from PTC Therapeutics), HTT227 is …

    Stage
    Phase 3
    Ages
    21 to 70
    Site
    Beth Israel Deaconess Med Ctr, Boston, Massachusetts
    Locations
    117 in total
    Run by
    Novartis Pharmaceuticals

    See if you can join NCT07326709 on ClinicalTrials.gov

  3. A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

    The main goal of this study is to evaluate the safety, tolerability, and preliminary efficacy of SPK-10001 in participants with Huntington's Disease.

    Stage
    Phase 1
    Ages
    25 to 65
    Site
    Beth Israel Deaconess Medical Center, Boston, Massachusetts
    Locations
    5 in total
    Run by
    Hoffmann-La Roche

    See if you can join NCT06826612 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.