HIV Infections Clinical Trials

46 studies are recruiting for hiv infections in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Assessing the Use of MY-RIDE, a Just-in-time Adaptive Intervention, to Improve HIV Prevention and Substance Use in Youth Experiencing Homelessness

   The purpose of this study is to determine whether Motivating Youth to Reduce Infections, Disconnections, and Emotion dysregulation (MY-RIDE) decreases substance use , to determine whether MY-RIDE increases human immunodeficiency virus (HIV) prevention strategies and to evaluate MY-RIDE effects on w…

   Stage

   Not phased

   Ages

   18 to 25

   Site

   The University of Texas Health Science Center at Houston, Houston, Texas

   Run by

   The University of Texas Health Science Center, Houston

   See if you can join NCT06074354 on ClinicalTrials.gov

2. Women Focused Encounters for Resilience Independence Strength and Eudaimonia

   The goal of this combination Type 1 hybrid and observational study is to evaluate the impact of a peer delivered intervention of acceptance and commitment therapy (ACT) + exercise + social support to address the substance (ab)use, violence, and AIDS/HIV (SAVA) to improve medication adherence for wo…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UC San Diego AntiViral Research Center (AVRC), San Diego, California

   Run by

   University of California, San Diego

   See if you can join NCT06216600 on ClinicalTrials.gov

3. The Test-to-PrEP Study

   To compare the effectiveness of two social network strategies (direct distribution and referral-based distribution) in increasing HIV self-testing (HIVST) completion rates among social network contacts of current Pre-Exposure Prophylaxis (PrEP) clients.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Miami, Miami, Florida

   Run by

   University of Miami

   See if you can join NCT06927856 on ClinicalTrials.gov

4. IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)

   The scientific premise of this research is that individual, interpersonal, and structural factors impact Black girls' sexual reproductive health outcomes (sexually transmitted infection (STI) and Human Immunodeficiency Virus (HIV)) and experience of sexual violence. This study expands STI/HIV preve…

   Stage

   Not phased

   Ages

   13 and older

   Site

   University of Illinois Chicago, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT06266416 on ClinicalTrials.gov

5. Teamwork Makes the Dream Work

   Exploring the effect of team-based ARTAS intervention in an inpatient setting on HIV linkage to care and hospital readmission rates.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Loma Linda University Medical Center, Loma Linda, California

   Run by

   Loma Linda University

   See if you can join NCT05866523 on ClinicalTrials.gov

6. Comprehensive HIV and Harm Prevention Via Telehealth

   The purpose of this study is to test 2 different ways to offer medications to prevent human immunodeficiency virus (HIV), cure hepatitis C virus (HCV) (if applicable) and treat substance use disorder (if desired) in people who inject drugs.

   Stage

   Not phased

   Ages

   18 and older

   Site

   IDEA Miami, Miami, Florida

   Locations

   2 in total

   Run by

   University of Miami

   See if you can join NCT05897099 on ClinicalTrials.gov

7. A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants

   This is an open-label, dose-escalation study to investigate the safety, tolerability and pharmacokinetics (PK) of single subcutaneous (SC) administration of long acting (LA) Cabotegravir (CAB) 200 milligrams per milliliter (mg/mL) with Recombinant Human Hyaluronidase PH20 (rHuPH20) (Part A), a sing…

   Stage

   Phase 1

   Ages

   18 to 55

   Site

   GSK Investigational Site, Las Vegas, Nevada

   Locations

   3 in total

   Run by

   ViiV Healthcare

   See if you can join NCT05418868 on ClinicalTrials.gov

8. Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

   This is a randomized placebo-controlled study in treated and suppressed HIV-infected individuals aged ≥40 years with either known CVD or 1 CVD risk factor to study the effect of Bempedoic acid (BA) on safety, arterial inflammation as assessed by FDG-PET/CT, lipids, inflammation, immune activation, …

   Stage

   Phase 2

   Ages

   40 and older

   Site

   UCLA Center for Clinical AIDS Research and Education (CARE), Los Angeles, California

   Locations

   3 in total

   Run by

   Priscilla Hsue, MD

   See if you can join NCT05488431 on ClinicalTrials.gov

9. Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV

   People aging with HIV are at higher risk for Alzheimer's disease and related dementias, and although physical activity is a promising target to mitigate such risk, this population engages in low levels of physical activity. Few studies have tested cognitive effects of exercise interventions or exam…

   Stage

   Not phased

   Ages

   50 to 80

   Site

   University of Colorado Denver, Aurora, Colorado

   Locations

   3 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06013579 on ClinicalTrials.gov

10. Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

    The goal of this clinical trial is to evaluate the effectiveness of a social network intervention to recruit people who inject drugs and their networks for HIV testing and linkage to HIV prevention and treatment services in Maryland. Study aims are to determine the effectiveness of a social network…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Frederick County Health Department, Street Safe Program, Frederick, Maryland

    Locations

    2 in total

    Run by

    Johns Hopkins University

    See if you can join NCT06103370 on ClinicalTrials.gov

11. Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)

    This randomized Type 1 hybrid effectiveness-implementation trial (N=186) will evaluate the effectiveness and implementation of a peer-delivered problem solving and behavioral activation intervention for adherence to LAI-PrEP/ART ("Peer Activate-LAI") compared to enhanced treatment as usual (ETAU) f…

    Stage

    Not phased

    Ages

    18 to 88

    Site

    HIPS (Harm reduction drop-in center), Washington D.C., District of Columbia

    Locations

    2 in total

    Run by

    University of Maryland, Baltimore

    See if you can join NCT06501781 on ClinicalTrials.gov

12. A Study to Assess the Safety, Tolerability, and Pharmacokinetics of VH4011499 Compared to Placebo in Adults Without HIV

    The purpose of this study is to investigate safety, pharmacokinetics and tolerability following single ascending dose (SAD) and multiple ascending doses (MAD) of VH4011499 administered subcutaneously (SC) and intramuscularly (IM) in participants without HIV.

    Stage

    Phase 1

    Ages

    18 to 55

    Site

    GSK Investigational Site, Las Vegas, Nevada

    Locations

    2 in total

    Run by

    ViiV Healthcare

    See if you can join NCT06724640 on ClinicalTrials.gov

13. HIV Treatment Adherence Dose Determination Trial

    The proposed research will conduct the first dose-determination trial to find the optimal number of behavioral counseling sessions (dose) needed to achieve and sustain optimal HIV treatment adherence. The results of this study will determine how much intervention is needed for whom and at what cost…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Connecticut, Storrs, Connecticut

    Locations

    2 in total

    Run by

    University of Connecticut

    See if you can join NCT04577313 on ClinicalTrials.gov

14. Vaccine Immunity and Inflammation in the Aging Person Living With HIV

    This study will track immune responsiveness to conjugate pneumococcal vaccines over time to help determine how long protection from this vaccine lasts in individuals with chronic medical conditions (in this study - HIV) and with age.

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Hennepin Healthcare System, Minneapolis, Minnesota

    Run by

    Hennepin Healthcare Research Institute

    See if you can join NCT06514547 on ClinicalTrials.gov

15. Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.

    The purpose of the Antiretroviral Pregnancy Registry (Registry) is to detect any major teratogenic effect involving any of the Registry drugs when administered to pregnant people. Registration is voluntary and confidential with information obtained from the health care provider. A Registry-assigned…

    Stage

    Not phased

    Ages

    12 to 60

    Site

    Registry Coordinating Center, Wilmington, North Carolina

    Run by

    Syneos Health

    See if you can join NCT00404989 on ClinicalTrials.gov

16. TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk

    Ecological momentary interventions (EMI), which use phones to deliver messages to reduce alcohol use and related risk behaviors during or prior to drinking events, can help to address triggers in real-time. GPS tracking can determine when individuals visit places they have previously reported drink…

    Stage

    Not phased

    Ages

    18 to 35

    Site

    Yale University, New Haven, Connecticut

    Locations

    2 in total

    Run by

    University of Kentucky

    See if you can join NCT05576350 on ClinicalTrials.gov

17. Imaging Immune Activation in HIV by PET-MR

    This is a single center exploratory imaging study involving one intravenous microdose of [18F]F-AraG followed by whole-body positron emission tomography-magnetic resonance (PET-MR) imaging in HIV infected individuals to determine the anatomical distribution of the PET tracer. Participants will be e…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of California, San Francisco, San Francisco, California

    Run by

    CellSight Technologies, Inc.

    See if you can join NCT03684655 on ClinicalTrials.gov

18. Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics

    The purpose of this study is to provide data on the pharmacokinetic (PK), safety, tolerability, efficacy and acceptability of this fixed dose combination (FDC) single tablet 2-drug regimen for virologically suppressed (HIV-1 RNA [Ribonucleic Acid] < 50 [cells per milliliter] c/mL) children 6 to les…

    Stage

    Phase 1

    Ages

    6 to 12

    Site

    GSK Investigational Site, Long Beach, California

    Locations

    8 in total

    Run by

    ViiV Healthcare

    See if you can join NCT05674656 on ClinicalTrials.gov

19. Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

    This randomized control trial study among Pre-exposure prophylactic users (PrEP) aims to learn and determine the efficacy of Screening, brief intervention, and referral to treatment (SBRIT) in reducing the risk of alcohol use. The main questions it aims to answer are: 1. How alcohol use impacts the…

    Stage

    Not phased

    Ages

    18 to 85

    Site

    University of Louisville, Louisville, Kentucky

    Run by

    Shirish S Barve

    See if you can join NCT06005298 on ClinicalTrials.gov

20. Keeping it LITE: Exploring HIV Risk in Vulnerable Youth With Limited Interaction and Digital Health Intervention

    Despite advances in HIV diagnostics, care and prevention strategies, infection rates among adolescent and young adult sexual and gender minorities (SGM) continue to rise in the United States (US). There is an urgent need to describe the epidemiology and trajectories of HIV acquisition in this popul…

    Stage

    Not phased

    Ages

    13 to 34

    Site

    John H. Stroger, Jr. Hospital of Cook County, Chicago, Illinois

    Run by

    Hektoen Institute for Medical Research

    See if you can join NCT05848570 on ClinicalTrials.gov

21. Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention

    The purpose of this study is to compare the effectiveness of two mobile health technologies (text messaging or a mobile app) designed to help people take HIV pre-exposure prophylaxis (PrEP) as directed by the clinic. PrEP is the use of a daily anti-HIV medications by HIV-negative people to help pre…

    Stage

    Not phased

    Ages

    15 and older

    Site

    San Francisco AIDS Foundation, San Francisco, California

    Locations

    4 in total

    Run by

    Public Health Foundation Enterprises, Inc.

    See if you can join NCT04855773 on ClinicalTrials.gov