Heart Failure Clinical Trials in Chapel Hill, North Carolina

5 studies are recruiting for heart failure in Chapel Hill, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

    The purpose of this study is to find out if the investigational drug called omecamtiv mecarbil can reduce the risk of the effects of heart failure, like hospitalization, transplantation, or death in patients with heart failure and severely reduced ejection fraction.

    Stage
    Phase 3
    Ages
    18 to 85
    Site
    Clinical and Translational Research Center - University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    Locations
    205 in total
    Run by
    Cytokinetics

    See if you can join NCT06736574 on ClinicalTrials.gov

  2. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

    Stage
    Not phased
    Ages
    0 to 20
    Site
    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    Locations
    52 in total
    Run by
    Duke University

    See if you can join NCT04278404 on ClinicalTrials.gov

  3. A Study of LY3971297 in Participants With Heart Failure

    The main purpose of this study is to assess how well LY3971297 is tolerated and what side effects may occur in participants with heart failure with preserved ejection fraction (HFpEF) and participants with heart failure with reduced ejection fraction (HFrEF). Blood tests will be performed to invest…

    Stage
    Phase 1
    Ages
    18 to 65
    Site
    University of North Carolina, Division of Cardiology, Chapel Hill, North Carolina
    Locations
    12 in total
    Run by
    Eli Lilly and Company

    See if you can join NCT07547540 on ClinicalTrials.gov

  4. Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

    The purpose of TEAM-HF IDE clinical trial is to evaluate safety and effectiveness of the HeartMate 3 LVAS compared to guideline directed medical therapy (GDMT) in a population of ambulatory advanced heart failure patients who are not dependent on intravenous inotrope.

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    Locations
    68 in total
    Run by
    Abbott Medical Devices

    See if you can join NCT06526195 on ClinicalTrials.gov

  5. Left vs Left Randomized Clinical Trial

    The investigators aim to prospectively test the comparative effectiveness of His or Left bundle branch pacing in relation to patient centered outcomes (quality of life, physical activity, heart failure hospitalization, mortality) and comparative safety in relation to device-related complications an…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of North Carolina, Chapel Hill, North Carolina
    Locations
    71 in total
    Run by
    Baylor College of Medicine

    See if you can join NCT05650658 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.