Glaucoma Clinical Trials

42 studies are recruiting for glaucoma in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.

   The objective of this study is to evaluate ocular outflow dynamics of the eye using intraoperative tonographic biometry and assess its predictive value in improving postoperative outcomes.

   Stage

   Not phased

   Ages

   18 and older

   Site

   New York Eye and Ear Infirmary of Mount Sinai, New York, New York

   Run by

   The New York Eye & Ear Infirmary

   See if you can join NCT07425496 on ClinicalTrials.gov

2. Data Gathering for A10900

   The objective of this study is to gather Optical Coherence Tomography (OCT) data on normal and diseased eyes

   Stage

   Not phased

   Ages

   22 and older

   Site

   Ketchum Health, Anaheim, California

   Locations

   4 in total

   Run by

   Optos, PLC

   See if you can join NCT07149740 on ClinicalTrials.gov

3. Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers

   The goal of this clinical trial is to learn if implementation of an eye screening program at Federally Qualified Health Center (FQHC) clinics provides results that participants may have glaucoma, and/or other eye conditions (diabetic retinopathy, cataract, visual acuity impairment). The glaucoma sc…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06629649 on ClinicalTrials.gov

4. Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2

   To compare eye disease detection rates at a Federally Qualified Health Center between a technology-enhanced protocol and standard optometric clinical examination for three of the leading causes of blindness: glaucoma, diabetic retinopathy, and visually significant cataract.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Hamilton Optometry Clinic, Flint, Michigan

   Run by

   University of Michigan

   See if you can join NCT06934577 on ClinicalTrials.gov

5. Retinal Blood Flow and Autoregulation

   The purpose of this study is to establish autoregulation of retinal blood flow in arterioles and capillaries as a biomarker for early primary open angle glaucoma.

   Stage

   Phase 4

   Ages

   18 to 88

   Site

   University of Maryland Faculty Physicians, Inc, Baltimore, Maryland

   Locations

   4 in total

   Run by

   University of Maryland, Baltimore

   See if you can join NCT05344274 on ClinicalTrials.gov

6. Topical Insulin for Glaucoma

   The purpose of this Phase 1 trial is to determine the safety over 1-2 months of topic sterile human recombinant insulin on subjects with optic neuropathies (glaucoma, ischecmic optic neuropathy, and optic disc drusen).

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Byers Eye Institute at Stanford University, Palo Alto, California

   Run by

   Stanford University

   See if you can join NCT05206877 on ClinicalTrials.gov

7. Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%/Latanoprost 0.005% to Treat Glaucoma

   To evaluate the effect of brimonidine tartrate 0.025% on conjunctival hyperemia in patients treated with netarsudil 0.02%/latanoprost 0.005% mono-therapy for intraocular pressure lowering.

   Stage

   Phase 4

   Ages

   18 to 65

   Site

   Vision Source, Kansas City, Missouri

   Run by

   Insight Eyecare Specialties, Inc. dba Vision Source Eyecare,

   See if you can join NCT07209410 on ClinicalTrials.gov

8. Pilocarpine Use After Kahook Goniotomy

   The goal of this study is to determine whether using pilocarpine provides added benefit to the success of combined cataract + Kahook Dual Blade (KDB) surgery.

   Stage

   Phase 3

   Ages

   30 to 100

   Site

   Montefiore Wakefield Campus, The Bronx, New York

   Locations

   2 in total

   Run by

   Montefiore Medical Center

   See if you can join NCT03933631 on ClinicalTrials.gov

9. Electrical Stimulation for Vision Neuroenhancement in Glaucoma

   The purpose of the study is to evaluate the efficacy, transorbital alternating current stimulation (rtACS) using the EYETRONIC for the treatment in patients with glaucoma.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Byers Eye Institute at Stanford University, Palo Alto, California

   Run by

   Stanford University

   See if you can join NCT06685211 on ClinicalTrials.gov

10. Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)

    This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension undergoing cataract surgery.

    Stage

    Phase 3

    Ages

    22 and older

    Site

    Houston Eye Associates, Houston, Texas

    Run by

    SpyGlass Pharma, Inc.

    See if you can join NCT07218783 on ClinicalTrials.gov

11. Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)

    This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension undergoing cataract surgery.

    Stage

    Phase 3

    Ages

    22 and older

    Site

    R and R Eye Research, LLC, San Antonio, Texas

    Run by

    SpyGlass Pharma, Inc.

    See if you can join NCT07218796 on ClinicalTrials.gov

12. A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients

    Background Glaucoma is a progressive optic neuropathy characterized by elevated intraocular pressure (IOP), leading to irreversible vision loss. Current treatment strategies often involve medications, which can be challenging for patients due to adherence issues and side effects. Direct Selective L…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Shafer Vision Institute, Plymouth Meeting, Pennsylvania

    Run by

    Brian Shafer

    See if you can join NCT07076303 on ClinicalTrials.gov

13. Electrical Stimulation for the Treatment of Optic Neuropathies

    The overall aim of this study is to see whether long-term electrical stimulation with a home-stimulation device works well and is safe for the treatment of open-angle glaucoma. Open-Angle Glaucoma is a disease where the nerves in the back of your eye die off faster than expected regardless of your …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Byers Eye Institute, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT05626426 on ClinicalTrials.gov

14. Hyperbaric Oxygen Therapy for Optic Neuropathies

    The purpose of the study is to evaluate the neuroprotective efficacy of hyperbaric oxygen for the treatment in patients with optic neuropathy.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Byers Eye Institute, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT06128720 on ClinicalTrials.gov

15. Glaucoma Laser Assessment of Stability and Sustainability

    The GLASS Study is designed to help researchers learn whether repeating a non-invasive laser treatment called DSLT (Direct Selective Laser Trabeculoplasty) can better control eye pressure in patients with early-stage glaucoma or ocular hypertension. All participants will receive the laser treatment…

    Stage

    Not phased

    Ages

    40 and older

    Site

    Twin Cities Eye Consultants, Coon Rapids, Minnesota

    Run by

    Twin Cities Eye Consultants

    See if you can join NCT06963684 on ClinicalTrials.gov

16. Novel Glaucoma Diagnostics

    The purpose of this research is to evaluate novel technologies for the assessment of ocular structure and function, including the scanning device called Optical Coherence Tomography (OCT). We will test the OCT and other devices in their ability to image diseases of the eye and also compare the meas…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Wills Eye Hospital, Philadelphia, Pennsylvania

    Run by

    Wills Eye

    See if you can join NCT00286637 on ClinicalTrials.gov

17. Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma

    Prospective, multicenter, single-arm study of the iStent infinite in adult pseudophakic or phakic subjects with mild to moderate primary open angle glaucoma who have not failed conventional medical and surgical treatment

    Stage

    Not phased

    Ages

    35 and older

    Site

    Glaukos Investigator Site, Cincinnati, Ohio

    Run by

    Glaukos Corporation

    See if you can join NCT06057051 on ClinicalTrials.gov