Epilepsy Clinical Trials in Boston, Massachusetts

13 studies are recruiting for epilepsy in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

   This will be a prospective, open-label, single-arm, multi-center, pilot study to evaluate the safety, tolerability, and preliminary efficacy of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with drug-resistant unilateral or bilateral temporal lobe epilepsy…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   3 in total

   Run by

   NaviFUS Corporation

   See if you can join NCT06388707 on ClinicalTrials.gov

2. Diagnosing Epilepsy To EffeCT Change

   The purpose of this research is to address the challenges of diagnosing and long-term management of epilepsy in participants whose seizures are not well captured by standard electroencephalography (EEG) tests and who cannot use or are not able to use more standard monitoring techniques. This resear…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   21 in total

   Run by

   Epiminder America, Inc.

   See if you can join NCT07110337 on ClinicalTrials.gov

3. Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

   The purpose of this research is to address the challenges of correctly monitoring, managing, and diagnosing epilepsy in participants whose seizures are not well captured by standard electroencephalography (EEG) tests and who cannot use or are not able to use more standard monitoring techniques. Thi…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   18 in total

   Run by

   Epiminder America, Inc.

   See if you can join NCT07110454 on ClinicalTrials.gov

4. Subcortical Arousal in Perceptual Awareness

   The study consists of prospective enrollment of healthy participants and patients with epilepsy, as well as analysis of an existing data set. Healthy participants will be studied with fMRI, eye metrics and behavioral testing at Yale. Patients will be studied with intracranial thalamic and cortical …

   Stage

   Not phased

   Ages

   13 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   8 in total

   Run by

   Yale University

   See if you can join NCT06934356 on ClinicalTrials.gov

5. Computational Neuroscience of Language Processing in the Human Brain

   Language is a signature human cognitive skill, but the precise computations that support language understanding remain unknown. This study aims to combine high-quality human neural data obtained through intracranial recordings with advances in computational modeling of human cognition to shed light…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT05222594 on ClinicalTrials.gov

6. Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

   Methylphenidate (MPH) is a stimulant, FDA-approved for the treatment of attention deficit hyperactivity disorder (ADHD). It is unknown, however, if stimulants would be of benefit for memory and thinking problems due to epilepsy. In this study, participants will be assigned randomly (i.e., by flip o…

   Stage

   Phase 4

   Ages

   18 and older

   Site

   VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts

   Locations

   4 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT04419272 on ClinicalTrials.gov

7. A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

   The Epilepsy-Dyskinesia Study aims to advance the understanding of the clinical and molecular spectrum of epilepsy-dyskinesia syndromes, monogenic diseases that cause both movement disorders and epilepsy. Addressing challenges in rare disease research -such as small, geographically dispersed patien…

   Stage

   Not phased

   Ages

   0 to 18

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT06585605 on ClinicalTrials.gov

8. Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

   This trial is a Phase II randomized, double-blind, placebo controlled multi-site study to evaluate the safety and efficacy of early sirolimus to prevent or delay seizure onset in TSC infants. This study is supported by research funding from the Office of Orphan Products Division (OOPD) of the US Fo…

   Stage

   Phase 2

   Ages

   0 to 0

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Locations

   11 in total

   Run by

   Darcy Krueger

   See if you can join NCT05104983 on ClinicalTrials.gov

9. Genetics of Epilepsy and Related Disorders

   Investigators at Boston Children's Hospital are conducting research in order to better understand the genetic factors which may contribute to epilepsy and related disorders. These findings may help explain the broad spectrum of clinical characteristics and outcomes seen in people with epilepsy.

   Stage

   Not phased

   Ages

   Any age

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT01858285 on ClinicalTrials.gov

10. Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)

    Concurrent electroencephalography (EEG) and new tripolar EEG (tEEG) will be recorded from adult and pediatric patients. In some patients stereo EEG (sEEG) will also be recorded concurrently.

    Stage

    Not phased

    Ages

    6 and older

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    CREmedical

    See if you can join NCT05944692 on ClinicalTrials.gov

11. Registry and Natural History of Epilepsy-Dyskinesia Syndromes

    The Registry and Natural History of Epilepsy-Dyskinesia Syndromes is focused on gathering longitudinal clinical data as well as biological samples (blood, urine, and/or skin/tissue) from male and female patients, of all ages, who have a genetic diagnosis of epilepsy-dyskinesia syndromes. Through pr…

    Stage

    Not phased

    Ages

    0 to 30

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Run by

    Boston Children's Hospital

    See if you can join NCT06967727 on ClinicalTrials.gov

12. Epilepsy Learning Healthcare System (ELHS)

    The Epilepsy Learning Health System (ELHS) is a quality improvement and research network to improve outcomes for people with epilepsy. The ELHS is designed as a model of value-based chronic care for epilepsy as envisioned by the National Academies of Medicine Committee in their landmark reports "Th…

    Stage

    Not phased

    Ages

    Any age

    Site

    Partners - Massachusetts General Hospital Epilepsy Service (MGH)/ Partners - Brigham and Women's (BWH), Boston, Massachusetts

    Locations

    13 in total

    Run by

    Epilepsy Foundation of America

    See if you can join NCT06265103 on ClinicalTrials.gov

13. Human Epilepsy Genetics--Neuronal Migration Disorders Study

    The purpose of this study is to identify genes responsible for epilepsy, brain malformations and disorders of human cognition.

    Stage

    Not phased

    Ages

    Any age

    Site

    Boston Children's Hospital, Walsh Laboratory, Boston, Massachusetts

    Run by

    Harvard University Faculty of Medicine

    See if you can join NCT00041600 on ClinicalTrials.gov