Epilepsy Clinical Trials in Bethesda, Maryland

7 studies are recruiting for epilepsy in Bethesda, Maryland right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database

   Objectives: The overall study objective is to compare the sensitivities and specificities of morphometric analysis techniques using structural MRI images based on pre- and postsurgical localization of epileptic foci in patients undergoing presurgical evaluation for medically refractory epilepsy. To…

   Stage

   Not phased

   Ages

   8 to 120

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Neurological Disorders and Stroke (NINDS)

   See if you can join NCT02107989 on ClinicalTrials.gov

2. Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy

   Background: - The blood-brain barrier separates the brain from the rest of the body. Epilepsy is a neurological disease that causes seizures. It can affect this barrier. Researchers think a contrast agent called mangafodipir might be better able to show areas of the brain that epilepsy affects. Obj…

   Stage

   Phase 1

   Ages

   18 to 60

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Neurological Disorders and Stroke (NINDS)

   See if you can join NCT02531880 on ClinicalTrials.gov

3. Surgery as a Treatment for Medically Intractable Epilepsy

   Background: - Drug resistant epilepsy is the term used to describe epilepsy that cannot be controlled by medication. Many people whose seizures do not respond to medication will respond to surgical treatment, relieving seizures completely or almost completely in one-half to two-thirds of patients w…

   Stage

   Not phased

   Ages

   8 to 99

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Neurological Disorders and Stroke (NINDS)

   See if you can join NCT01273129 on ClinicalTrials.gov

4. Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

   This is a clinical research study for an investigational drug called RAP-219 in adult participants with focal seizures. This study is being conducted to determine if RAP-219 is safe and effective in reducing focal seizure frequency.

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Mid-Atlantic Epilepsy and Sleep Center, Bethesda, Maryland

   Locations

   11 in total

   Run by

   Rapport Therapeutics Inc.

   See if you can join NCT07563881 on ClinicalTrials.gov

5. Tumor Related Epilepsy

   Background: Some people with brain tumors have seizures related to the tumor. This is called tumor-related epilepsy. Usually brain tumors are treated by removing as much of the brain tumor as possible without causing problems. Researchers think this may improve the outcome for people with brain tum…

   Stage

   Not phased

   Ages

   8 to 99

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Neurological Disorders and Stroke (NINDS)

   See if you can join NCT02639325 on ClinicalTrials.gov

6. MEHMO Natural History and Biomarkers

   This observational natural history study will follow individuals with MEHMO (Mental disability, Epileptic seizure, Hypopituitarism/Hypogenitalism, Microcephaly, Obesity) syndrome or an eIF2-pathway related disorder, who have symptoms such as intellectual delay, seizures, abnormal hormone and blood …

   Stage

   Not phased

   Ages

   0 to 100

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

   See if you can join NCT06019182 on ClinicalTrials.gov

7. Investigating Epilepsy: Screening and Evaluation

   Background: Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want people who have diagnosed or suspected epilepsy to participate in ongoing studies. They want to learn more about clinical care for epilepsy. The…

   Stage

   Not phased

   Ages

   8 to 110

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Neurological Disorders and Stroke (NINDS)

   See if you can join NCT03478852 on ClinicalTrials.gov