End Stage Renal Disease Clinical Trials in Boston, Massachusetts

8 studies are recruiting for end stage renal disease in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Partners Calciphylaxis Biobank

   Calciphylaxis, a vascular calcification disorder, is a rare and serious disorder characterized by calcification of dermal arterioles. There are significant gaps in the understanding of the pathophysiology and risk factors for calciphylaxis. At present, there is no effective treatment. Uncertain pat…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT03032835 on ClinicalTrials.gov

2. Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula

   VasQ is an external support implant for arteriovenous fistulas created for dialysis access. This is a postmarket surveillance, prospective, multi-center, randomized, controlled, open label trial enrolling 300 patients randomized into two study arms: * Treatment arm: End to side fistula supported wi…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   9 in total

   Run by

   Laminate Medical Technologies

   See if you can join NCT06516653 on ClinicalTrials.gov

3. Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

   This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultrasound when used under a protocol of biweekly use for assessing fistula maturation and reducing time to Clinical Maturation.

   Stage

   Not phased

   Ages

   18 to 84

   Site

   Boston Medical Center, Boston, Massachusetts

   Locations

   21 in total

   Run by

   Sonavex, Inc.

   See if you can join NCT06190717 on ClinicalTrials.gov

4. SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

   This is a prospective, randomized, multi-center clinical trial for chronic kidney disease (CKD) patients referred for creation of a new arteriovenous fistula (AVF) in order to assess the safety and effectiveness of SelfWrap, a bioabsorbable perivascular wrap.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   28 in total

   Run by

   VenoStent

   See if you can join NCT06001827 on ClinicalTrials.gov

5. CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

   The investigators aim to determine, using a point-of-care randomized controlled trial design, if hemodialysis patients, who are randomized to metoprolol succinate (a dialyzable, beta-1 selective beta blocker), have an improved cardiovascular outcome compared to those randomized to carvedilol (a non…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts

   Locations

   8 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT05931276 on ClinicalTrials.gov

6. Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

   The aim of this study is to evaluate DCR-PHXC in participants with PH1 and severe renal impairment, with or without dialysis.

   Stage

   Phase 2

   Ages

   Any age

   Site

   Clinical Trial Site, Boston, Massachusetts

   Locations

   18 in total

   Run by

   Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

   See if you can join NCT04580420 on ClinicalTrials.gov

7. Safety and Efficacy of Empagliflozin in Hemodialysis

   A 12-week, phase II, randomized, double-blind, placebo-controlled, multi-center study to assess the safety, tolerability, and preliminary efficacy of empagliflozin versus placebo among patients initiating hemodialysis (n=60) for the treatment of end-stage kidney disease.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   NYU Langone Health

   See if you can join NCT05786443 on ClinicalTrials.gov

8. Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis

   Hemodialysis represents a life line of patients with end stage renal disease, who are commonly maintained on hemodialysis through catheters. Prolonged exposure to these catheters eventually damages the walls of veins, which results in stenosis at the local site. This condition is called central ven…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Boston Medical Center, Boston, Massachusetts

   Run by

   Boston Medical Center

   See if you can join NCT04399941 on ClinicalTrials.gov