End Stage Renal Disease Clinical Trials

19 studies are recruiting for end stage renal disease in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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By city

Boston, Massachusetts 8 Houston, Texas 5 Dallas, Texas 4 Memphis, Tennessee 3 Raleigh, North Carolina 3

Studies now recruiting

  1. Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry

    Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,

    Stage
    Not phased
    Ages
    18 and older
    Site
    Infirmary Heath, Mobile, Alabama
    Locations
    4 in total
    Run by
    LifeNet Health

    See if you can join NCT05880537 on ClinicalTrials.gov

  2. Partners Calciphylaxis Biobank

    Calciphylaxis, a vascular calcification disorder, is a rare and serious disorder characterized by calcification of dermal arterioles. There are significant gaps in the understanding of the pathophysiology and risk factors for calciphylaxis. At present, there is no effective treatment. Uncertain pat…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT03032835 on ClinicalTrials.gov

  3. Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

    A prospective, single-arm, multi-center post-market surveillance study of the BD® WavelinQ™ EndoAVF System for the Creation of Arteriovenous (AV) Fistula in Patients Requiring Dialysis.

    Stage
    Not phased
    Ages
    18 and older
    Site
    California Institute of Renal Research, La Jolla, California
    Locations
    17 in total
    Run by
    C. R. Bard

    See if you can join NCT04634916 on ClinicalTrials.gov

  4. Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

    Kidney failure has been recognized as one of the most costly chronic conditions among United States Veterans. Approximately 13,000 Veterans develop kidney failure each year, and most require hemodialysis initiation. Hemodialysis patients suffer significantly increased risk of death and hospitalizat…

    Stage
    Not phased
    Ages
    18 and older
    Site
    VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas, Texas
    Run by
    VA Office of Research and Development

    See if you can join NCT04163614 on ClinicalTrials.gov

  5. CAPABLE Transplant

    The purpose of this mixed methods study is to adapt CAPABLE as CAPABLE Transplant to accomplish two things: 1) To resolve barriers to being classified as active on the Kidney Transplant (KT) waitlist, 2) as a surgical prehabilitation intervention targeting the pre-frail/ frail KT waitlist populatio…

    Stage
    Not phased
    Ages
    18 to 99
    Site
    Johns Hopkins School of Nursing, Baltimore, Maryland
    Run by
    Johns Hopkins University

    See if you can join NCT06326905 on ClinicalTrials.gov

  6. Post Market Study for VasQ, an External Support Implant for Arteriovenous Fistula

    VasQ is an external support implant for arteriovenous fistulas created for dialysis access. This is a postmarket surveillance, prospective, multi-center, randomized, controlled, open label trial enrolling 300 patients randomized into two study arms: * Treatment arm: End to side fistula supported wi…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    Fresenius Vascular Care Long Beach, Long Beach, California
    Locations
    9 in total
    Run by
    Laminate Medical Technologies

    See if you can join NCT06516653 on ClinicalTrials.gov

  7. AMSC for Reducing Anastomotic Stenosis in Primary Arteriovenous Anastomoses

    Researchers are evaluating the safety of allogeneic Adipose Derived Mesenchymal Stem Cells (AMSC) use during hemodialysis arteriovenous fistula and arterial bypass creation and its efficacy on improving access maturation and primary anastomotic patency.

    Stage
    Phase 1
    Ages
    18 to 85
    Site
    Mayo Clinic in Florida, Jacksonville, Florida
    Run by
    Houssam Farres, M.D.

    See if you can join NCT04392206 on ClinicalTrials.gov

  8. PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis

    The goal of this observational study is to increase the understanding of the safety and performance of Merit Medical's HeRO Graft System (HeRO) and Super HeRO Adaptor and Support Seal System (Super HeRO) devices. This study includes adults that are being treated with one of these devices as part of…

    Stage
    Not phased
    Ages
    18 and older
    Site
    MedStar Washington Hospital Center, Washington D.C., District of Columbia
    Locations
    7 in total
    Run by
    Merit Medical Systems, Inc.

    See if you can join NCT06422871 on ClinicalTrials.gov

  9. Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

    This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultrasound when used under a protocol of biweekly use for assessing fistula maturation and reducing time to Clinical Maturation.

    Stage
    Not phased
    Ages
    18 to 84
    Site
    Trinity Research Group, Dothan, Alabama
    Locations
    21 in total
    Run by
    Sonavex, Inc.

    See if you can join NCT06190717 on ClinicalTrials.gov

  10. Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile

    This will be a single center, prospective, open-label, randomized, controlled trial comparing Envarsus XR® to twice-daily tacrolimus. The targeted population will be patients with end stage renal disease listed for primary solitary kidney transplant. Transplant Surgery is not part of the study.

    Stage
    Phase 2
    Ages
    18 to 75
    Site
    Deepa Valvi, Lexington, Kentucky
    Run by
    Roberto Gedaly

    See if you can join NCT03321656 on ClinicalTrials.gov

  11. SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

    This is a prospective, randomized, multi-center clinical trial for chronic kidney disease (CKD) patients referred for creation of a new arteriovenous fistula (AVF) in order to assess the safety and effectiveness of SelfWrap, a bioabsorbable perivascular wrap.

    Stage
    Not phased
    Ages
    18 and older
    Site
    AKDHC Bullhead City, Bullhead City, Arizona
    Locations
    28 in total
    Run by
    VenoStent

    See if you can join NCT06001827 on ClinicalTrials.gov

  12. Drug Interaction Potential of Pro-Inflammatory Conditions

    Pro-inflammatory cytokines, which are elevated in pro-inflammatory disease states (e.g., type II diabetes mellitus [T2DM], irritable bowel diseases [IBD], and end stage renal disease [ESRD]) have been shown to inhibit hepatic drug-metabolizing enzymes, including members of the cytochrome P450 (CYP)…

    Stage
    Not phased
    Ages
    12 to 99
    Site
    Indiana University Hospital, Indianapolis, Indiana
    Run by
    Indiana University

    See if you can join NCT07360938 on ClinicalTrials.gov

  13. CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

    The investigators aim to determine, using a point-of-care randomized controlled trial design, if hemodialysis patients, who are randomized to metoprolol succinate (a dialyzable, beta-1 selective beta blocker), have an improved cardiovascular outcome compared to those randomized to carvedilol (a non…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    VA Long Beach Healthcare System, Long Beach, CA, Long Beach, California
    Locations
    8 in total
    Run by
    VA Office of Research and Development

    See if you can join NCT05931276 on ClinicalTrials.gov

  14. CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease

    Frailty and sarcopenia are modifiable risk factors for morbidity and mortality in patients with ESRD. Exercise is the recommended intervention to prevent frailty and sarcopenia, however, many clinical trials have shown limited clinical improvement in muscle mass and physical function. We propose th…

    Stage
    Phase 3
    Ages
    18 to 75
    Site
    Vanderbilt University Medical Center-GCRC, Nashville, Tennessee
    Locations
    2 in total
    Run by
    Vanderbilt University Medical Center

    See if you can join NCT05422534 on ClinicalTrials.gov

  15. Safety & Efficacy of DCR-PHXC in Patients With PH1 and ESRD

    The aim of this study is to evaluate DCR-PHXC in participants with PH1 and severe renal impairment, with or without dialysis.

    Stage
    Phase 2
    Ages
    Any age
    Site
    Clinical Trial Site, Rochester, Minnesota
    Locations
    18 in total
    Run by
    Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

    See if you can join NCT04580420 on ClinicalTrials.gov

  16. Safety and Efficacy of Empagliflozin in Hemodialysis

    A 12-week, phase II, randomized, double-blind, placebo-controlled, multi-center study to assess the safety, tolerability, and preliminary efficacy of empagliflozin versus placebo among patients initiating hemodialysis (n=60) for the treatment of end-stage kidney disease.

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Brigham and Women's Hospital, Boston, Massachusetts
    Locations
    2 in total
    Run by
    NYU Langone Health

    See if you can join NCT05786443 on ClinicalTrials.gov

  17. Intravascular Ultrasound in Patients With End-stage Renal Disease on Dialysis

    Hemodialysis represents a life line of patients with end stage renal disease, who are commonly maintained on hemodialysis through catheters. Prolonged exposure to these catheters eventually damages the walls of veins, which results in stenosis at the local site. This condition is called central ven…

    Stage
    Not phased
    Ages
    18 to 85
    Site
    Boston Medical Center, Boston, Massachusetts
    Run by
    Boston Medical Center

    See if you can join NCT04399941 on ClinicalTrials.gov

  18. Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

    This study utilizes a web-based application to help patients on the organ transplant waitlist communicate patient's need for a living donor via social media and provide interested potential donors the opportunity to engage with the evaluation process.

    Stage
    Not phased
    Ages
    18 and older
    Site
    The Johns Hopkins Hospital, Baltimore, Maryland
    Locations
    6 in total
    Run by
    Johns Hopkins University

    See if you can join NCT03803423 on ClinicalTrials.gov

  19. Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

    The U.S. Department of Health and Human Services (HHS), through the National Institutes of Health (NIH), published Final Human Immunodeficiency Virus (HIV) Organ Policy Equity (HOPE) Act Safeguards and Research Criteria for Transplantation of Organs Infected With HIV. All such transplants must occu…

    Stage
    Not phased
    Ages
    18 and older
    Site
    East Jefferson General Hospital, Metairie, Louisiana
    Run by
    Tulane University

    See if you can join NCT05159466 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.