Down Syndrome Clinical Trials in Los Angeles, California

4 studies are recruiting for down syndrome in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

   The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   14 in total

   Run by

   Sequenom, Inc.

   See if you can join NCT01429389 on ClinicalTrials.gov

2. A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

   This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed). Down syndrome patients with relapsed B-ALL are included in this study. Blinatumoma…

   Stage

   Phase 2

   Ages

   1 to 30

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Locations

   227 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT04546399 on ClinicalTrials.gov

3. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

   The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

   Stage

   Not phased

   Ages

   0 to 20

   Site

   University of California, Los Angeles Medical Center, Los Angeles, California

   Locations

   52 in total

   Run by

   Duke University

   See if you can join NCT04278404 on ClinicalTrials.gov

4. Down Syndrome Obstructive Sleep Apnea

   The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) with moderate to severe Obstructive Sleep Apnea (OSA).

   Stage

   Phase 2

   Ages

   5 to 18

   Site

   Children's Hospital of Los Angeles, Los Angeles, California

   Locations

   7 in total

   Run by

   Brigham and Women's Hospital

   See if you can join NCT06043440 on ClinicalTrials.gov