Diabetic Foot Ulcer Clinical Trials

36 studies are recruiting for diabetic foot ulcer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.

   The goal of this investigational study is to evaluate the safety and clinical performance of Tropocells Autologous Platelet-rich Fibrin (PRF) for wound care for both males and females, ages 18-80 years old, with Grade 1 and 2, mild to moderate, neuroischemic diabetic chronic foot ulcers in subjects…

   Stage

   Phase 2

   Ages

   18 to 80

   Site

   WoundCentrics Wound Care & Hyperbarics -Corpus Christi - Shoreline, Corpus Christi, Texas

   Locations

   2 in total

   Run by

   Estar Medical dba Medical Technologies, LTD

   See if you can join NCT06810726 on ClinicalTrials.gov

2. Adapting Lifestyle Offloading for DFUs

   The goal of this pilot clinical trial is to develop and test a tailored occupational therapist-led lifestyle-focused intervention to aid patients in improving diabetic foot ulcer care. The main questions it aims to answer are to determine the acceptability and feasibility of taking a tailored lifes…

   Stage

   Not phased

   Ages

   21 and older

   Site

   University of Southern California, Los Angeles, California

   Run by

   University of Southern California

   See if you can join NCT06278935 on ClinicalTrials.gov

3. A Study to Evaluate the Efficacy of a Purified Native Type 1 Collagen Extracellular Matrix With Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers

   This prospective, multi-center, randomized, controlled modified platform Trial compares Purified Native Type 1 Collagen Extracellular Matrix with Polyhexamethylene Biguanide Antimicrobial (PCMP) and Standard of Care versus Standard of Care Alone in subjects with chronic DFUs.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Kent State University, College of Podiatric Medicine, Clevland, Ohio

   Run by

   Organogenesis

   See if you can join NCT06618612 on ClinicalTrials.gov

4. A Phase 2a Proof of Concept Open-Label, Randomized, Controlled Study to Evaluate the Safety and Efficacy of MDI-1228-mesylate Gel Compared With Standard of Care Alone in Patients With Diabetic Foot Ulcers

   The study will evaluate the treatment effect of MDI-1228-mesylate Gel compared with standard of care alone for the complete healing rate at the end of 12 weeks in participants with diabetic foot ulcers (targeted ulcer). In addition, the proportion of subjects whose target ulcer area is reduced by 5…

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Site 001, Durham, North Carolina

   Run by

   Zhuhai Rui-Inno Pharmaceutical Technology Co., Ltd.

   See if you can join NCT06852976 on ClinicalTrials.gov

5. Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

   Title A Multicenter, Prospective, Randomized Controlled Modified Multi-Platform (Matriarch) Trial Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care versus Standard of Care alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

   Stage

   Phase 4

   Ages

   21 and older

   Site

   Serena Group, Monroeville, Pennsylvania

   Run by

   Tiger Biosciences, LLC.

   See if you can join NCT06826339 on ClinicalTrials.gov

6. Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers

   The purpose of this study is to evaluate the efficacy of dehydrated human amnion membrane (dhAM) and standard of care (SOC) versus SOC alone in the closure of nonhealing diabetic foot ulcers (DFUs).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Performance Foot and Ankle Specialists, Thousand Oaks, California

   Run by

   Axolotl Biologix

   See if you can join NCT06550596 on ClinicalTrials.gov

7. Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs

   This is a multicenter, prospective, randomized controlled modified multi-platform (matriarch) trial evaluating several cellular, acellular, and matrix-like products (CAMPs) and standard of care versus standard of care alone in the management of nonhealing diabetic foot and venous leg ulcers.

   Stage

   Not phased

   Ages

   21 and older

   Site

   Cutting Edge Research, Circleville, Ohio

   Run by

   Stability Biologics

   See if you can join NCT06560502 on ClinicalTrials.gov

8. Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center

   Prospective, single-blinded, single-center, parallel group, randomized controlled trial (RCT) to assess rate and frequency of wound healing and associated financial savings, when using Medaxis debritom+ versus standard of care as a choice of debridement method, where both arms follow normal wound c…

   Stage

   Not phased

   Ages

   18 and older

   Site

   MCR Health, Inc., Bradenton, Florida

   Run by

   Medaxis, LLC

   See if you can join NCT04920253 on ClinicalTrials.gov

9. Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care Versus Standard of Care

   A Randomized Controlled Multicenter Clinical Trial, Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care versus Standard of Care alone in the management of Nonhealing Diabetic Foot Ulcers

   Stage

   Not phased

   Ages

   18 and older

   Site

   Detroit Foot and Ankle, Clinton Township, Michigan

   Run by

   Applied Biologics, LLC

   See if you can join NCT06564831 on ClinicalTrials.gov

10. Modified Platform Trial Evaluating PpLHACM and SOC Versus SOC Alone in the Treatment of Nonhealing DFUs

    This study will evaluate two human amnion/chorion membrane (ppLHACM) products and Standard of Care (SOC) versus SOC alone in the closure of nonhealing diabetic foot ulcers (DFUs).

    Stage

    Not phased

    Ages

    18 and older

    Site

    SerenaGroup - Monroeville, Monroeville, Pennsylvania

    Run by

    MiMedx Group, Inc.

    See if you can join NCT06600724 on ClinicalTrials.gov

11. A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing.

    The goal of this clinical trial is to follow the progress of wounds in those with venous leg ulcers and diabetic foot ulcers while using an absorbent dressing called Mepilex Up. The main objective is to follow the progress of these wounds over time from initial visit to each follow-up visit. Partic…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Center for Clinical Research, Inc., Castro Valley, California

    Locations

    4 in total

    Run by

    Molnlycke Health Care AB

    See if you can join NCT05588583 on ClinicalTrials.gov