Diabetes Mellitus, Type 2 Clinical Trials

58 studies are recruiting for diabetes mellitus, type 2 in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

   Sixteen institutions will be selected from a HRSA uniform data system and have data collected for up to 3 years. Eight institutions will begin the iPATH practice transformation during year one, the other eight institutions will begin iPATH in year two. FQHC administrators, clinicians and staff will…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Board of Trustees of the Leland Stanford Junior University, Stanford, California

   Locations

   4 in total

   Run by

   Stanford University

   See if you can join NCT06251323 on ClinicalTrials.gov

2. Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature

   A prospective, multicenter evaluation of performance and safety of the Eversense Gemini System with flash glucose measurement feature. The purpose of this clinical investigation is to evaluate the accuracy of the Gemini System with new technological flash glucose monitoring (FGM) feature enhancemen…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Headlands Research - AMCR Institute, Escondido, California

   Run by

   Senseonics, Inc.

   See if you can join NCT07386340 on ClinicalTrials.gov

3. ROME GS System Study

   The purpose of this clinical investigation is to demonstrate that the proposed physical changes to the ROME GS Sensor do not have any adverse impact on safety and performance when compared to the Eversense 365 Sensor.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Headlands Research - AMCR Institute, Escondido, California

   Locations

   4 in total

   Run by

   Senseonics, Inc.

   See if you can join NCT07518004 on ClinicalTrials.gov

4. Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

   This study is to investigate how adipocyte (fat cell) function and fat distribution differ between individuals with normal-weight type 2 diabetes (NWD), those with overweight type 2 diabetes (OWD), and normal-weight controls without diabetes (NWC). The study will assess whether adipocyte-directed t…

   Stage

   Phase 4

   Ages

   30 to 70

   Site

   Stanford University, Palo Alto, California

   Locations

   2 in total

   Run by

   Stanford University

   See if you can join NCT06657209 on ClinicalTrials.gov

5. Boosting Emotional Well-being and Happiness in Outpatients Living With Diabetes

   The focus of this study is to test the efficacy of an 8-week, remotely delivered, positive-psychology-motivational interviewing (PP-MI) intervention, with additional twice weekly text messages for a total of 16 weeks (with interactive, algorithm-driven, goal-focused text messages in the final 8 wee…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT05420051 on ClinicalTrials.gov

6. Project Dulce for Arab Americans With Type 2 Diabetes

   Arab Americans (AA) face many challenges in diabetes self-management due to the limited educational resources and support available for them. The cultural and linguistic barriers between patients and health care providers lead to poor diabetes management and outcomes. This study (Project Dulce Arab…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Metro Caring, Denver, Colorado

   Locations

   2 in total

   Run by

   Scripps Whittier Diabetes Institute

   See if you can join NCT05580536 on ClinicalTrials.gov

7. Transformative Research in Diabetic Nephropathy 2.0

   The goal of this observational study is to learn more about kidney health in adults with diabetic kidney disease and other groups. Researchers will study kidney tissue and other samples. They want to learn how sodium-glucose cotransporter-2 (SGLT2) inhibitors, a type of diabetes medicine, may affec…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Penn Presbyterian Medical Center, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT07444203 on ClinicalTrials.gov

8. Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes

   The goal of this study is to pilot test features of a new smartphone app and to gather feedback related to wearing a continuous glucose monitor (CGM) and a Fitbit device, as well as to obtain input on health behavior-focused messages delivered through the app. The study will enroll English-speaking…

   Stage

   Not phased

   Ages

   16 to 24

   Site

   Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT07270016 on ClinicalTrials.gov

9. Blood Markers of Early Pancreas Cancer

   Identifying biomarkers of early pancreatic ductal adenocarcinoma (PDAC) could facilitate screening for individuals at higher than average risk and expedite the diagnosis in individuals with symptoms and substantially improve an individual's chance of surviving the disease. The investigators propose…

   Stage

   Not phased

   Ages

   19 and older

   Site

   Unversity of Nebraska Medical Center, Omaha, Nebraska

   Run by

   University of Nebraska

   See if you can join NCT03568630 on ClinicalTrials.gov

10. Use of CGM in Kidney Transplant Recipients

    The investigators want to study the impact CGM (continuous glucose monitoring) has on patients glycemic control as determined by time in range (TIR 70-180 mg/dL) in the Diabetic Kidney Transplant population.

    Stage

    Not phased

    Ages

    18 and older

    Site

    UC Davis Health, Sacramento, California

    Run by

    University of California, Davis

    See if you can join NCT04783441 on ClinicalTrials.gov

11. Drug Interaction Potential of Pro-Inflammatory Conditions

    Pro-inflammatory cytokines, which are elevated in pro-inflammatory disease states (e.g., type II diabetes mellitus [T2DM], irritable bowel diseases [IBD], and end stage renal disease [ESRD]) have been shown to inhibit hepatic drug-metabolizing enzymes, including members of the cytochrome P450 (CYP)…

    Stage

    Not phased

    Ages

    12 to 99

    Site

    Indiana University Hospital, Indianapolis, Indiana

    Run by

    Indiana University

    See if you can join NCT07360938 on ClinicalTrials.gov

12. Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships

    The goal of this study is to develop, implement, and evaluate a patient-centered triage and referral model designed to improve health outcomes for individuals with uncontrolled type 2 diabetes mellitus (T2DM) and unmet health-related social needs. The intervention builds on the existing THRIVE infr…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Boston Medical Center, Boston, Massachusetts

    Run by

    Boston Medical Center

    See if you can join NCT07043426 on ClinicalTrials.gov

13. Family Model DSME in FBOs in the RMI

    Health disparities in the Republic of the Marshall Islands are striking, with extremely high rates of type 2 diabetes. Documented prevalence of type 2 diabetes in the Marshall Islands ranges from 20%-50%.This is significantly higher than the global (8.5%) and United States (11%) prevalence. Diabete…

    Stage

    Not phased

    Ages

    18 and older

    Site

    UAMS Institute for Community Health Innovation, Springdale, Arkansas

    Run by

    University of Arkansas

    See if you can join NCT05502016 on ClinicalTrials.gov

14. Post Prandial Individual Responses to Different Foods

    This study aims to understand why people respond differently to the same foods, especially when it comes to changes in blood sugar after eating. A continuous glucose monitors (CGMs) will be used to observe how individuals respond to specific meals and drinks (e.g., Oral Glucose Tolerance Test, OGTT…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT06989164 on ClinicalTrials.gov

15. SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

    Peripheral arterial disease (PAD) affects over 230 million adults worldwide and is a highly morbid, costly, and disabling condition. Ischemic leg pain drives disability in PAD patients and results from oxygen supply-demand mismatch, autonomic dysfunction, and muscle breakdown. This leg pain, which …

    Stage

    Not phased

    Ages

    19 to 89

    Site

    University of Nebraska Medical Center, Omaha, Nebraska

    Run by

    University of Nebraska

    See if you can join NCT06480786 on ClinicalTrials.gov

16. Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

    The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and the subsequent benefit of improving type II diabetes outcomes in a low socioeconomic Hispanic population. This study will involve a 6-month long commitment where participants w…

    Stage

    Not phased

    Ages

    18 to 64

    Site

    San Diego State University, San Diego, California

    Run by

    San Diego State University

    See if you can join NCT05279729 on ClinicalTrials.gov

17. Efficacy of Using Mobile Health Applications for Health

    The purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes and type II diabetes outcomes in type 2 diabetics. This study will involve a 6-month long commitment where participants will be expected to weigh themselves every morning, at the s…

    Stage

    Not phased

    Ages

    18 to 64

    Site

    San Diego State University, San Diego, California

    Run by

    San Diego State University

    See if you can join NCT05589155 on ClinicalTrials.gov

18. MANAGe-DM: Novel Nurse Case Management to Improve Diabetes Outcomes in Formerly Incarcerated Black Men

    The study is a randomized control trial involving 100 participants (formerly incarcerated Black men with poorly controlled diabetes) to examine the effect of a tailored nurse case manager on glycemic control and other clinical outcomes, self-care behaviors, and quality of life at 6 months post-rand…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Center for Advancing Population Science, Medical College of Wisconsin, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT06031428 on ClinicalTrials.gov

19. Phenotyping Genetic Risk for Type 2 Diabetes

    This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2 diabetes.

    Stage

    Not phased

    Ages

    10 to 70

    Site

    University of Pennsylvania, Philadelphia, Pennsylvania

    Locations

    2 in total

    Run by

    University of Pennsylvania

    See if you can join NCT04024631 on ClinicalTrials.gov

20. Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

    HYPOTHESIS: Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have distinct pathophysiologic etiologies. Therefore, therapeutic interventions designed to correct the specific underlying pathogenic abnormalities in IGT and IFG will be required to optimally prevent the progressive b…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    The University of Texas Health Science Center at San Antonio, San Antonio, Texas

    Run by

    The University of Texas Health Science Center at San Antonio

    See if you can join NCT02969798 on ClinicalTrials.gov

21. Linking Education, Produce Provision, and Community Referrals to Improve Diabetes Care (LINK)

    This is a pragmatic randomized controlled trial (pRCT) that aims to test the effect of produce provision, diabetes education, and community referrals on hemoglobin A1c levels in individuals with type 2 diabetes experiencing food insecurity.

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University Wexner Medical Center, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT05472441 on ClinicalTrials.gov

22. Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes

    The objective of this study is to assess the effects of Hass Avocados on glycemic control. The investigators hypothesize that Hass Avocado consumption will reduce fasting blood sugar compared to an isocaloric amount of other fruit during controlled feeding.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Pennington Biomedical Research Center, Baton Rouge, Louisiana

    Run by

    Pennington Biomedical Research Center

    See if you can join NCT05958368 on ClinicalTrials.gov

23. Impact of a Diabetes Education Mobile Web Application on Patients With Uncontrolled Type 2 Diabetes

    The goal of this clinical trial is to evaluate the use and effectiveness of a mobile web application (app) that is designed to educate and allow patients to manage diabetes and make sustainable lifestyle changes, and to study the impact of the app on clinical outcomes of diabetes (HA1C) and educati…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Reading Hospital, an affiliate of Tower Health, West Reading, Pennsylvania

    Run by

    The Reading Hospital and Medical Center

    See if you can join NCT05893927 on ClinicalTrials.gov

24. Diabetes Learning in Virtual Environments Just in Time for Community Reentry

    The proposed study will use a randomized clinical trial design with non-equivalent control group and longitudinal design to evaluate the feasibility, acceptability, and preliminary effects of the Diabetes LIVE JustICE application. The design will incorporate repeated measures at 0, 6, and 12 weeks.…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Connecticut, Storrs, Connecticut

    Locations

    2 in total

    Run by

    Louise Reagan

    See if you can join NCT05286892 on ClinicalTrials.gov

25. Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

    High-resistance, short-duration inspiratory muscle strength training (IMST) is a novel lifestyle intervention involving 30 inhalations against a resistive load which requires only ~5 min/day and is thus ideal for youth with T2D (Y-T2D). Investigators seek to 1: assess changes in casual and 24-hr SB…

    Stage

    Not phased

    Ages

    14 to 40

    Site

    Seattle Children's Hospital, Seattle, Washington

    Locations

    2 in total

    Run by

    Seattle Children's Hospital

    See if you can join NCT06936670 on ClinicalTrials.gov