Diabetes Mellitus, Type 1 Clinical Trials in Chicago, Illinois

6 studies are recruiting for diabetes mellitus, type 1 in Chicago, Illinois right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes

   This study will evaluate the safety, tolerability and efficacy of VX-880 infusion and VX-017 infusion in participants with type 1 diabetes (T1D) and impaired awareness of hypoglycemia (IAH) and severe hypoglycemia.

   Stage

   Phase 3

   Ages

   18 to 65

   Site

   University of Chicago, Chicago, Illinois

   Locations

   29 in total

   Run by

   Vertex Pharmaceuticals Incorporated

   See if you can join NCT04786262 on ClinicalTrials.gov

2. A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

   This study is First In Human study for Encapsulated Porcine Islet Cells for Xenotransplantation (OPF-310). The purpose of this study to assess the safety, tolerability, and efficacy of OPF-310 transplantation and to define the recommended Phase 2 dose (RP2D) in adult subjects with unstable Type 1 D…

   Stage

   Phase 1

   Ages

   35 to 70

   Site

   University of Illinois Hospital & Health Sciences System, Chicago, Illinois

   Run by

   Otsuka Pharmaceutical Factory, Inc.

   See if you can join NCT06575426 on ClinicalTrials.gov

3. Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

   Powerful new drugs that can prevent or delay end stage kidney disease (ESKD) - so called sodium-glucose cotransporter-2 inhibitors (SGLT2i) - are now available for patients with type 2 diabetes. Whether these drugs have similar effects in patients with type 1 diabetes (T1D) remains unknown because …

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Northwestern University Feinberg School of Medicine, Chicago, Illinois

   Locations

   19 in total

   Run by

   Alessandro Doria

   See if you can join NCT06217302 on ClinicalTrials.gov

4. CBTi for the Treatment of Insomnia in Type 1 Diabetes

   The goal of this study is to learn if treating insomnia with a therapy intervention in people with type 1 diabetes will help to better control sugar levels, sleep, and quality of life. The questions this study aims to answer include: Will this intervention help the insomnia symptoms? Will obtaining…

   Stage

   EARLY_Phase 1

   Ages

   18 to 65

   Site

   University of Illinois Chicago, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT07091318 on ClinicalTrials.gov

5. Islet Transplantation in Patients With "Brittle" Type I Diabetes

   The purpose of this study is to learn about the safety of islet transplantation for Type 1 diabetes mellitus, which may provide more normal control of blood sugar without the need for insulin shots. Islets are special clusters of cells within the pancreas that produce insulin. These cells will be o…

   Stage

   Not phased

   Ages

   18 to 70

   Site

   University of Chicago Medical Center, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT01630850 on ClinicalTrials.gov

6. Islet Transplantation in Type 1 Diabetic Kidney Allograft

   The purpose of this study is to learn about the safety of islet transplantation when performed after kidney transplantation, which may provide more normal control of blood sugar without the need for insulin shots. Islets are special clusters of cells within the pancreas that produce insulin. These …

   Stage

   Phase 2

   Ages

   18 to 68

   Site

   The University of Chicago, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT01241864 on ClinicalTrials.gov