Depression Clinical Trials in Pittsburgh, Pennsylvania

9 studies are recruiting for depression in Pittsburgh, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Apimostinel + Automated Neurocognitive Training for Depression

   Apimostinel shows initial promise as a novel rapid-acting antidepressant medication with minimal side effects or safety concerns. Cognitive Training (CT) is a digital intervention that has shown promise in extending the durability of another similar drug (ketamine). This randomized controlled trial…

   Stage

   Phase 2

   Ages

   18 to 60

   Site

   Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania

   Run by

   Rebecca Price

   See if you can join NCT06400121 on ClinicalTrials.gov

2. E-Mindfulness Approaches for Living After Breast Cancer

   NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs LO), and an app-based, self-paced version (MAPs App). Participants wi…

   Stage

   Phase 3

   Ages

   18 to 50

   Site

   UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania

   Locations

   383 in total

   Run by

   NRG Oncology

   See if you can join NCT06748222 on ClinicalTrials.gov

3. Sleep and Circadian Interventions for College Students at High Risk of Suicide

   The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide risk among high risk young adults. Investigators will evaluate three …

   Stage

   Not phased

   Ages

   18 to 25

   Site

   Western Psychiatric Hospital/University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT07346014 on ClinicalTrials.gov

4. Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

   The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior. Sleep difficulties are a promising target for youth with suicidal thoughts and behavior to focus on as a prev…

   Stage

   Not phased

   Ages

   12 to 18

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Locations

   2 in total

   Run by

   University of Pittsburgh

   See if you can join NCT06963463 on ClinicalTrials.gov

5. RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

   It is envisioned that multipronged benefits from this pilot work for the UPMC ISD and its members. It is expected the RxWell platform to provide the following benefits: expansion of the use of RxWell to all UPMC ISD members providing peri-operative mood management with advantage of improved peri-op…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   UPMC Shadyside, Pittsburgh, Pennsylvania

   Locations

   3 in total

   Run by

   University of Pittsburgh

   See if you can join NCT05658796 on ClinicalTrials.gov

6. Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments

   The goal of this clinical trial is to learn how different types of non-invasive brain stimulation affect mood and brain function in adults with major depressive disorder (MDD). It will also study how brain stimulation may work together with antidepressant treatments. The main questions this study a…

   Stage

   Not phased

   Ages

   18 to 55

   Site

   Bellefield Towers, Pittsburgh, Pennsylvania

   Run by

   Marta Peciña, MD PhD

   See if you can join NCT06976840 on ClinicalTrials.gov

7. Assessing Improvements in Mood and Sleep Trial

   This is a multi-site randomized control trial involving people age 55+ years who have current depression symptoms plus another suicide risk indicator (either current suicidal ideation or a past history of attempt). Our goal is evaluate which of two different approaches works best to improve things …

   Stage

   Not phased

   Ages

   55 and older

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Locations

   3 in total

   Run by

   University of Pittsburgh

   See if you can join NCT06639477 on ClinicalTrials.gov

8. Teen Brain Online II: Understanding How Social Media Affects the Teen Brain

   There has been much interest in the potential role of social media (SM) use in driving a current mental health crisis among teens, with a dire need for evidence that goes beyond self-report. One important avenue is to understand the role of the brain in driving the effects of SM use on emotional he…

   Stage

   Not phased

   Ages

   13 to 17

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06817993 on ClinicalTrials.gov

9. Parent Encouragement And Coaching of Happiness in Youth

   The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1. Characterize child neural reward response and its relation to maternal socializ…

   Stage

   Not phased

   Ages

   4 to 99

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06725160 on ClinicalTrials.gov