Depression Clinical Trials in New York, New York

21 studies are recruiting for depression in New York, New York right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

   The purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in patients with MDD. For more information about the EMBRACE study, including participating study locations, and to register your interest in learning more …

   Stage

   Phase 3

   Ages

   18 to 85

   Site

   New York State Psychiatric Institute, New York, New York

   Locations

   69 in total

   Run by

   Cybin IRL Limited

   See if you can join NCT06793397 on ClinicalTrials.gov

2. A Digital Intervention for Post-Stroke Depression and Executive Dysfunction

   Individuals with stroke commonly experience both depression and cognitive difficulties. The goal of this study is to evaluate the efficacy of a treatment that combines a digital therapeutic (an iPad-based cognitive training program) with learning cognitive strategies. The hypotheses are that this t…

   Stage

   Phase 2

   Ages

   50 to 79

   Site

   Weill Cornell Medical Center, New York, New York

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT05507138 on ClinicalTrials.gov

3. Psilocybin-Assisted Therapy for Intergenerational Trauma

   This is an open-label psilocybin-assisted therapy study that will examine the safety and tolerability of psilocybin-assisted therapy in the offspring of genocide survivors with mood and anxiety disorders. The study will also investigate the efficacy of psilocybin-assisted therapy in reducing sympto…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   The Parsons Research Center for Psychedelic Healing, New York, New York

   Run by

   Rachel Yehuda

   See if you can join NCT06899165 on ClinicalTrials.gov

4. Mobile Cognitive Behavioral Therapy for Stroke

   This study aims to assess the feasibility and acceptability of "MAYA", a mobile cognitive behavioral therapy app for anxiety and mood disorders, in adults who have had a stroke.

   Stage

   Not phased

   Ages

   40 to 79

   Site

   Weill Cornell Medicine, New York, New York

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT06689878 on ClinicalTrials.gov

5. E-Mindfulness Approaches for Living After Breast Cancer

   NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs LO), and an app-based, self-paced version (MAPs App). Participants wi…

   Stage

   Phase 3

   Ages

   18 to 50

   Site

   Mount Sinai Union Square, New York, New York

   Locations

   383 in total

   Run by

   NRG Oncology

   See if you can join NCT06748222 on ClinicalTrials.gov

6. Tele-PROTECT Therapy: Effectiveness, Empowerment, and Implementation

   The purpose of this randomized trial is to conduct a fully powered effectiveness trial of video-delivered PROTECT (Tele-PROTECT) compared to a video-delivered depression education (DepEd) control condition to be delivered to 140 English- and Spanish-speaking NYC elder abuse victims. Investigators h…

   Stage

   Not phased

   Ages

   60 and older

   Site

   Weill Cornell Medicine, New York, New York

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT06039930 on ClinicalTrials.gov

7. Assessment of Music Experiences in Navigating Depression Part 2

   This study is again looking at the use of music and music therapy experiences in navigating depression. The researchers will provide 11 sessions of music therapy and half will be followed by recitals at the Third Street School Music Settlement where the kids enrolled in our study will observe and i…

   Stage

   Not phased

   Ages

   7 to 15

   Site

   Mount Sinai Union Square, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT07218055 on ClinicalTrials.gov

8. Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)

   This project is a double-blind, sham-controlled, parallel-arm, randomized controlled trial. We will recruit n=170 people living with MS, who are experiencing an episode of depression in the context of a major depressive episode (MDE). Using our remotely supervised (RS) tDCS protocol, enrolled parti…

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   NYU Langone Health, New York, New York

   Run by

   NYU Langone Health

   See if you can join NCT06901687 on ClinicalTrials.gov

9. Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)

   This pilot study evaluates the feasibility, safety, and preliminary efficacy of home-based 60Hz intermittent light therapy in adults with a major depressive episode (MDE). Participants will be randomized in a 2:1 ratio to receive either active or sham 60Hz intermittent light stimulation for 30 minu…

   Stage

   Not phased

   Ages

   24 to 65

   Site

   NYU Langone Health, New York, New York

   Run by

   NYU Langone Health

   See if you can join NCT07111390 on ClinicalTrials.gov

10. tDCS: Sleep to Mood in Depression (S2M-D)

    The purpose of this study is to determine whether changes in sleep consolidation occur during home-based transcranial direct current stimulation (tDCS) in adults with moderate depression and whether these changes are temporally associated with improvements in depressive symptoms.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT07572526 on ClinicalTrials.gov

11. A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

    The goal of this clinical trial is to learn if a drug called TNX-102 SL works to treat moderate to severe major depressive disorder in adults. It will also learn about the safety of TNX-102 SL. The main questions it aims to answer are: Does TNX-102 SL improve depression symptoms according to a depr…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Ima Clinical Research - Nyc Midtown, New York, New York

    Locations

    25 in total

    Run by

    Tonix Pharmaceuticals, Inc.

    See if you can join NCT07621237 on ClinicalTrials.gov

12. Personalized Mobile Cognitive Behavioral Therapy Application

    This study aims to compare the effectiveness of a standard mobile cognitive behavioral therapy program to a personalized mobile cognitive behavioral therapy program that introduces new skills over a shorter period of time. Participants will use the Maya app for two days per week, at least 20 minute…

    Stage

    Not phased

    Ages

    18 to 25

    Site

    Weill Cornell Medical College, New York, New York

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT05699525 on ClinicalTrials.gov

13. Mobile CBT for Middle Aged and Older Adults

    This study aims to assess a mobile app called MAYA for use in middle-aged and older adults with anxiety or mood disorders. The MAYA app is designed to teach coping skills for anxiety and depression that are drawn from cognitive behavioral therapy. Participants will be asked to use the app for at le…

    Stage

    Not phased

    Ages

    40 and older

    Site

    Weill Cornell Medicine, New York, New York

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT05754151 on ClinicalTrials.gov

14. Safe Mothers, Safe Children Initiative

    The purpose of this study is to assess the efficacy of the combined interventions, Skills Training in Affective and Interpersonal Regulation (STAIR) and Parent-Child Interaction Therapy (PCIT) or P-STAIR, for treating maternal PTSD and reducing maltreatment recidivism.

    Stage

    Not phased

    Ages

    18 and older

    Site

    McSilver Institute for Poverty Policy and Research, New York, New York

    Run by

    New York University

    See if you can join NCT04752618 on ClinicalTrials.gov

15. Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality

    The investigators hypothesized that during the 9-week course of Engage \& Connect treatment there will be an increase in brain functions of the Positive Valence System which in turn will lead to reduction in suicidality.

    Stage

    Not phased

    Ages

    50 to 80

    Site

    Weill Cornell Medicine, New York, New York

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT05925322 on ClinicalTrials.gov

16. Readiness and Progress in Emotion Regulation Therapy

    This study is an open trial designed to examine individual changes that occur before, during, and after 6 modules of Emotion Regulation Therapy (ERT) delivered via telehealth for individuals in New York State who are experiencing elevated worry, rumination, or self-criticism.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Teachers College, Columbia University, New York, New York

    Run by

    Teachers College, Columbia University

    See if you can join NCT07478393 on ClinicalTrials.gov

17. Heart Rate Variability (HRV)-Guided Transcranial Direct Current Stimulation (tDCS)

    This technology development project will be informed and guided by initial data collection of human subject data. For this purpose, the investigators will recruit n=100 people with mild to moderate depression in a double-blinded, parallel-arm, sham-controlled data collection period administered at …

    Stage

    Not phased

    Ages

    18 to 65

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT06455527 on ClinicalTrials.gov

18. WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt

    The goal of this project is to test whether WellPATH-PREVENT (a novel, mobile psychosocial intervention) improves a specific aspect of emotion regulation, i.e., cognitive reappraisal ability, and reduces suicide risk in middle-aged and older adults (50-90 years old) who have been discharged after a…

    Stage

    Not phased

    Ages

    50 to 90

    Site

    New York Presbyterian Hospital/Weill Cornell Medicine, New York, New York

    Locations

    2 in total

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT05183230 on ClinicalTrials.gov

19. Brief Interventions for Coping with Distress

    This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training, and 3) a health and wellness education training.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Teachers College, Columbia University, New York, New York

    Run by

    Teachers College, Columbia University

    See if you can join NCT05779761 on ClinicalTrials.gov

20. Lay-Delivered Behavioral Activation in Senior Centers

    In response to large numbers of senior center clients who suffer untreated depression and the dearth of geriatric mental health providers, the investigators have simplified Behavioral Activation to be delivered by lay volunteers ("Do More, Feel Better"; DMFB). The focus of Behavioral Activation is …

    Stage

    Not phased

    Ages

    60 and older

    Site

    Hudson Guild Senior Center, New York, New York

    Locations

    25 in total

    Run by

    University of Washington

    See if you can join NCT04621877 on ClinicalTrials.gov

21. An Exploratory Study Examining Biopsychosocial Markers of Anxiety and Depression

    This research study is studying how thoughts, feelings, surroundings, and individual biology may contribute to why and how people experience anxiety or depression. We are trying to find out the wide variety of reasons that people may experience anxiety or depression, and why different people are he…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Singula Institute, 353 Lexington Avenue (Room 600), New York, New York

    Run by

    Singula Institute

    See if you can join NCT05466851 on ClinicalTrials.gov