Depression Clinical Trials in Charleston, South Carolina

12 studies are recruiting for depression in Charleston, South Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. taVNS or TMS or Both for Depression

   The purpose of the research is to test out a combined treatment for depression where the investigators stimulate a nerve in the ear while at the same time stimulate the brain with magnets. These treatments are called transcutaneous (through the skin) auricular (ear) vagus nerve stimulation (taVNS) …

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Medical University of South Carolina Institute of Psychiatry, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT05725239 on ClinicalTrials.gov

2. E-Mindfulness Approaches for Living After Breast Cancer

   NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs LO), and an app-based, self-paced version (MAPs App). Participants wi…

   Stage

   Phase 3

   Ages

   18 to 50

   Site

   Medical University of South Carolina, Charleston, South Carolina

   Locations

   383 in total

   Run by

   NRG Oncology

   See if you can join NCT06748222 on ClinicalTrials.gov

3. Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

   The purpose of this study is to demonstrate whether Behavioral Activation for depression delivered via home based telehealth (BA-HT) is effective in improving social and role functioning in Veterans recently discharged from Cardiovascular disease (CVD-related) inpatient care. Eligible participants …

   Stage

   Not phased

   Ages

   21 and older

   Site

   Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina

   Run by

   VA Office of Research and Development

   See if you can join NCT04877197 on ClinicalTrials.gov

4. RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

   In this research study, investigators examine how brain activity changes during tests of emotional processing, attention, and memory using multimodal neuroimaging methods including electroencephalography (EEG), functional magnetic resonance imaging (fMRI), and functional near-infrared spectroscopy …

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Medical Univeristy of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT05977439 on ClinicalTrials.gov

5. Optimizing Care for Cancer Survivors With Depression: Project 3

   The purpose of this research study is to evaluate different depression treatment approaches among cancer survivors. A cancer survivor is defined as anyone who is living and has been diagnosed with cancer. Participants will be randomly assigned to either receive a mobile app for depression treatment…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Medical University of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT06930729 on ClinicalTrials.gov

6. Digitally Enhanced Stepped-Care for Depression in Primary Care

   This pilot, three-arm randomized clinical trial (N=40; 2:1:1) will evaluate the feasibility and preliminary efficacy of a digitally enhanced stepped-care approach for depression treatment in primary care. Participants will be randomized to: (1) stepped-care beginning with a self-guided Behavioral A…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Medical University of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT07634705 on ClinicalTrials.gov

7. Mindfulness Training During Accelerated TMS for Depression

   This NIH-funded single-arm pilot tests the feasibility, acceptability, and preliminary effects of embedding brief guided mindfulness practice (via the Waking Up smartphone app) into the inter-session intervals of clinically administered accelerated intermittent theta-burst stimulation (aiTBS) for m…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   IOP, Charleston, South Carolina

   Locations

   2 in total

   Run by

   Medical University of South Carolina

   See if you can join NCT07369557 on ClinicalTrials.gov

8. IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)

   The purpose of this research study is to evaluate a mobile application (app) for depression treatment called "Moodivate" among cancer survivors. Moodivate was developed by our research team to assist with the treatment of depressed mood. Participants will be randomly assigned to either download the…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Medical University of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT06582784 on ClinicalTrials.gov

9. Transcranial Magnetic Stimulation for MCI

   The goal of this phase II study is to establish the dose-response curves of a safe and clinically feasible non-invasive brain stimulation technique (accelerated Transcranial Magnetic Stimulation (TMS)) to improve both depression and cognitive function in Mild Cognitive Impairment (MCI) patients wit…

   Stage

   Not phased

   Ages

   60 to 85

   Site

   Medical University of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT05992831 on ClinicalTrials.gov

10. Treatment of Depression Post-SCI

    Depression is more common after a spinal cord injury (SCI) than in the general population. Unfortunately, it is unknown how depression is typically treated in individuals with SCI or if commonly used treatment methods are effective. This study will investigate the safety and impact of a novel metho…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT04263285 on ClinicalTrials.gov

11. Dosing rTMS for Depression Post-SCI

    Depression is a leading cause of disability worldwide and is more commonly seen in individual's post-spinal cord injury (SCI) than in the general population. Depression post-SCI impacts an individuals' quality of life and recovery. It has been reported that among Veterans with an SCI, those without…

    Stage

    Not phased

    Ages

    18 to 60

    Site

    Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina

    Run by

    VA Office of Research and Development

    See if you can join NCT05553353 on ClinicalTrials.gov

12. fMRI Accelerated TMS Depression

    This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder (MDD) patients can track brain recovery of MDD patients over an accelerat…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    30 Bee Street, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT06562153 on ClinicalTrials.gov