Depression Clinical Trials in Boston, Massachusetts

15 studies are recruiting for depression in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Study on Allopregnanolone and Depression in Women Across the Menopause Transition

   This study aims to identify how enhanced allopregnanolone activity (via pregnenolone) affects behavior and neurobiology that may underlie perimenopausal depression.

   Stage

   Not phased

   Ages

   40 to 60

   Site

   Beth Israel Deaconess Medical Center, Boston, Massachusetts

   Run by

   Beth Israel Deaconess Medical Center

   See if you can join NCT06238700 on ClinicalTrials.gov

2. Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study

   The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and depression. The main questions it aims to answer in a later fully powered randomized controlled trial are: …

   Stage

   Not phased

   Ages

   50 to 120

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07118722 on ClinicalTrials.gov

3. E-Mindfulness Approaches for Living After Breast Cancer

   NRG-CC015 is a prospective, randomized phase III clinical trial to evaluate the efficacy of two distinct digital approaches for delivering a mindfulness-based intervention: a live, instructor-led version delivered over Zoom (MAPs LO), and an app-based, self-paced version (MAPs App). Participants wi…

   Stage

   Phase 3

   Ages

   18 to 50

   Site

   Tufts Medical Center, Boston, Massachusetts

   Locations

   383 in total

   Run by

   NRG Oncology

   See if you can join NCT06748222 on ClinicalTrials.gov

4. Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

   Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV. However, posttraumatic stress (associated with intimate partner violence and/or other traumas) and depression negatively impact…

   Stage

   Not phased

   Ages

   15 and older

   Site

   Boston University, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Boston University Charles River Campus

   See if you can join NCT05624931 on ClinicalTrials.gov

5. Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

   The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the >30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care enga…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06557005 on ClinicalTrials.gov

6. Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression

   This project explores whether heated yoga, sauna, and a mindfulness app reduce depressive symptoms

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07082998 on ClinicalTrials.gov

7. Implementing Depression and Adherence Treatment

   The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression. The main questions it aims to answer are: What proportion of patients start an evidence-based treatment fo…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   3 in total

   Run by

   University of Miami

   See if you can join NCT07032363 on ClinicalTrials.gov

8. Pilot Study of a Behavioral Program for Resident Depression in Skilled Nursing Facilities

   The goal of this clinical trial is to test a behavioral health program (Interventions for Stressful Transitions in Later Life, InSTILL, for Individuals) for skilled nursing facility residents. The main questions it aims to answer is whether the program is program is feasible, satisfactory, and help…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07655232 on ClinicalTrials.gov

9. Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

   Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal cord injuries, heart failure, myocardial infarctions, strokes, cancer, post-traumatic stress disorder, and depression. Studies have also demon…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Boston Medical Center, Trauma Inpatient Service, Boston, Massachusetts

   Run by

   Boston Medical Center

   See if you can join NCT06812247 on ClinicalTrials.gov

10. Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

    Posttraumatic stress disorder (PTSD) can have significant impairment on aspects of mental well-being (MWB) including functioning, loneliness, physical health, and quality of life. There are several evidence-based treatments (EBPs) effective in treating PTSD such as Cognitive Processing Therapy (CPT…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Fully online study, Boston, Massachusetts

    Run by

    Boston University

    See if you can join NCT07250061 on ClinicalTrials.gov

11. Buspirone and Melatonin for Depression Following Traumatic Brain Injury

    Traumatic brain injuries (TBIs) are common. Post-TBI depression is associated with anxiety, aggression, fatigue, distractibility, anger, irritability, and rumination. The current research group conducted a pilot clinical trial, which investigated the novel treatment combination of buspirone and mel…

    Stage

    Phase 4

    Ages

    18 to 64

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Massachusetts General Hospital

    See if you can join NCT04400266 on ClinicalTrials.gov

12. Cannabis, Linked Emotions, and Adolescent Risk Study

    The goal of this study is to disentangle relationships between acute cannabis use and withdrawal on proximal depression and suicide risk and recovery in adolescents ages 12-18 years by incorporating time-varying patterns of substance use, mood, and SI. This project aims to guide the development of …

    Stage

    Not phased

    Ages

    12 to 18

    Site

    Massachusetts General Hopsital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06576076 on ClinicalTrials.gov

13. Behavioral Health Program for Short-Stay Nursing Facility Residents & Care Partners

    The goal of this clinical trial is to test a behavioral health program (Interventions for Stressful Transitions in Later Life, InSTILL) for skilled nursing facility residents and their primary support person. The main questions it aims to answer is whether the program is program is feasible, satisf…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT07220486 on ClinicalTrials.gov

14. Mind-body Resilience Program for Cardiac Arrest Survivors and Their Caregivers: Recovering Together After Cardiac Arrest

    The purpose of this study is to pilot two resilience interventions for cardiac arrest survivors and their informal caregivers, Recovering Together after Cardiac Arrest 1 and Recovering Together after Cardiac Arrest 2 . The data the investigators gather in this study will be used to further refine t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT07143357 on ClinicalTrials.gov

15. Brain Connectivity in Depression

    This study originally included 140 subjects with medication-refractory depression undergoing 10 Hz transcranial magnetic stimulation (10Hz-TMS) to the left dorsal lateral prefrontal cortex (DLPFC), with the goal of having 60 completers with good quality data. Subjects were recruited from the TMS cl…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Locations

    4 in total

    Run by

    Brigham and Women's Hospital

    See if you can join NCT03276793 on ClinicalTrials.gov