Dementia Clinical Trials in Indianapolis, Indiana

7 studies are recruiting for dementia in Indianapolis, Indiana right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

   PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the …

   Stage

   Phase 4

   Ages

   75 and older

   Site

   Indianapolis VA Medical Center, Indianapolis, Indiana

   Locations

   106 in total

   Run by

   Duke University

   See if you can join NCT04262206 on ClinicalTrials.gov

2. Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

   The goal of this study is to test CGM ASSIST. This is a digital tool that uses an interactive information display-an easy-to-read screen designed to help people with dementia (or memory loss) and diabetes, as well as their caregivers and doctors. Managing diabetes is often difficult for people with…

   Stage

   Not phased

   Ages

   65 and older

   Site

   Eskenazi Health, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT05643144 on ClinicalTrials.gov

3. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

   The purpose is to evaluate the biomarker effect, safety, and tolerability of investigational study drugs in participants who are known to have an Alzheimer's disease (AD)-causing mutation. Stage 1 will determine if treatment with the study drug prevents or slows the rate of amyloid beta (Aβ) pathol…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Indiana University School of Medicine, Indianapolis, Indiana

   Locations

   37 in total

   Run by

   Washington University School of Medicine

   See if you can join NCT05552157 on ClinicalTrials.gov

4. A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

   The purpose of this research study is to test the study drug, referred to as remternetug, to determine its effectiveness for the study treatment of asymptomatic (at risk) Alzheimer disease in individuals with AD-causing mutations. This study will also investigate the effects of remternetug on bioma…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Indiana University School of Medicine, Indianapolis, Indiana

   Locations

   37 in total

   Run by

   Washington University School of Medicine

   See if you can join NCT06647498 on ClinicalTrials.gov

5. A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

   The main purpose of this study is to determine if participants who previously took donanemab get clinical benefit when they receive annual doses. For each participant, the study will last up to 2.5 years and will include 6 visits.

   Stage

   Phase 3

   Ages

   55 and older

   Site

   Care Access - South Indianapolis, Indianapolis, Indiana

   Locations

   59 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07602582 on ClinicalTrials.gov

6. Trial-Ready Cohort-Down Syndrome (TRC-DS)

   The purpose of the Trial-Ready Cohort - Down Syndrome (TRC-DS) is to enroll 120 healthy adults with Down syndrome (DS), between the ages of 25-55, into a trial ready cohort (TRC), and up to 550 participants in total including co-enrolled in the Alzheimer Biomarkers Consortium - Down Syndrome (ABC-D…

   Stage

   Not phased

   Ages

   25 to 55

   Site

   Indiana University, Indianapolis, Indiana

   Locations

   22 in total

   Run by

   University of Southern California

   See if you can join NCT04165109 on ClinicalTrials.gov

7. Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

   The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and Related Dementias (ADRD). SVR is designed to help older adults improve…

   Stage

   Not phased

   Ages

   65 and older

   Site

   Sidney & Lois Eskenazi Hospital, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT07499570 on ClinicalTrials.gov