Dementia Clinical Trials in Boston, Massachusetts

6 studies are recruiting for dementia in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium

   The goal of this prospective cohort study is to assess potential differences in sleep biomarkers in older adult patients undergoing major orthopedic surgery. The main questions it aims to answer are: 1. To define sleep/circadian biomarkers of delirium (sleep duration, regularity, stability and timi…

   Stage

   Not phased

   Ages

   70 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06052397 on ClinicalTrials.gov

2. Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

   PREVENTABLE is a multi-center, randomized, parallel group, placebo-controlled superiority study. Participants will be randomized 1:1 to atorvastatin 40 mg or placebo. This large study conducted in community-dwelling older adults without cardiovascular disease (CVD) or dementia will demonstrate the …

   Stage

   Phase 4

   Ages

   75 and older

   Site

   VA Boston Healthcare System, Boston, Massachusetts

   Locations

   106 in total

   Run by

   Duke University

   See if you can join NCT04262206 on ClinicalTrials.gov

3. Trial-Ready Cohort-Down Syndrome (TRC-DS)

   The purpose of the Trial-Ready Cohort - Down Syndrome (TRC-DS) is to enroll 120 healthy adults with Down syndrome (DS), between the ages of 25-55, into a trial ready cohort (TRC), and up to 550 participants in total including co-enrolled in the Alzheimer Biomarkers Consortium - Down Syndrome (ABC-D…

   Stage

   Not phased

   Ages

   25 to 55

   Site

   Massachusetts General Hospital, Co-Enrolling through ABC-DS Only, Boston, Massachusetts

   Locations

   22 in total

   Run by

   University of Southern California

   See if you can join NCT04165109 on ClinicalTrials.gov

4. Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

   This phase 2a study will research the safety and tolerability of Foralumab, a human anti-CD3 antibody. An antibody is a molecule secreted by the immune system. These molecules are created to identify a specific pathogen. Previous data on experimental mice has suggested that Foralumab increases the …

   Stage

   Phase 2

   Ages

   60 to 85

   Site

   Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT06489548 on ClinicalTrials.gov

5. Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

   This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild dementia.

   Stage

   Not phased

   Ages

   55 and older

   Site

   Hinda and Arthur Marcus Institute for Aging Research, Boston, Massachusetts

   Run by

   Hebrew SeniorLife

   See if you can join NCT05661084 on ClinicalTrials.gov

6. Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

   The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize susp…

   Stage

   Not phased

   Ages

   60 to 106

   Site

   Hebrew SeniorLife, Boston, Massachusetts

   Run by

   Hebrew SeniorLife

   See if you can join NCT05950607 on ClinicalTrials.gov