Cystic Fibrosis Clinical Trials in Los Angeles, California

6 studies are recruiting for cystic fibrosis in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Impact of Sinus Surgery on Individuals With Cystic Fibrosis

   This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analy…

   Stage

   Not phased

   Ages

   18 to 99

   Site

   University of California, Los Angeles, Los Angeles, California

   Locations

   9 in total

   Run by

   University of California, Los Angeles

   See if you can join NCT04469439 on ClinicalTrials.gov

2. Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

   The STOP PEDS RCT is a multicenter, parallel, open label randomized controlled trial evaluating the long-term (one year) and short-term safety and efficacy of two antibiotic treatment strategies for the management of outpatient pulmonary exacerbations (PEx) in the pediatric CF population.

   Stage

   Not phased

   Ages

   3 to 18

   Site

   Children's Hospital of Los Angeles & Anton Yelchin Cystic Fibrosis Clinic, Los Angeles, California

   Locations

   33 in total

   Run by

   University of Washington, the Collaborative Health Studies Coordinating Center

   See if you can join NCT06654752 on ClinicalTrials.gov

3. Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

   The goal of this clinical trial is to learn if drug SPL84 is safe for adult patients with cystic fibrosis (CF). It will also learn if the drug works to treat works to treat CF with a specific mutation (3849 +10kb C-->T). The purpose of this research study is to test the safety and effectiveness of …

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Southern California, Los Angeles, California

   Locations

   3 in total

   Run by

   SpliSense Ltd.

   See if you can join NCT06429176 on ClinicalTrials.gov

4. Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

   ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy or are not taking CFTR modulators due to drug intolerance, poor response, or lack of access to modulators.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Children's Hospital of Los Angeles, Los Angeles, California

   Locations

   13 in total

   Run by

   Arcturus Therapeutics, Inc.

   See if you can join NCT06747858 on ClinicalTrials.gov

5. Maralixibat in Patients With Cystic Fibrosis and Constipation

   Chronic constipation is common in children with cystic fibrosis (CF), likely due to impaired chloride channel function that reduces intestinal secretions. Standard osmotic laxatives often provide inadequate relief in this population. Maralixibat is an ileal bile acid transporter inhibitor (IBATi) t…

   Stage

   Phase 2

   Ages

   1 to 18

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Run by

   Children's Hospital Los Angeles

   See if you can join NCT06413368 on ClinicalTrials.gov

6. A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

   The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR modulators. This data may be used to in…

   Stage

   Not phased

   Ages

   12 and older

   Site

   Childrens Hospital Los Angeles, Los Angeles, California

   Locations

   68 in total

   Run by

   Nicole Hamblett

   See if you can join NCT06504589 on ClinicalTrials.gov