Cystic Fibrosis Clinical Trials in Cincinnati, Ohio

10 studies are recruiting for cystic fibrosis in Cincinnati, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Sinus Disease in Young Children With Cystic Fibrosis

   This is a prospective, observational study examining the impact of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators on chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) in young children with cystic fibrosis (YCwCF). This study involves two groups: ch…

   Stage

   Not phased

   Ages

   2 to 8

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   6 in total

   Run by

   University of California, Los Angeles

   See if you can join NCT06191640 on ClinicalTrials.gov

2. Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis

   In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this population.

   Stage

   Not phased

   Ages

   18 to 45

   Site

   University of Cincinnati, Cincinnati, Ohio

   Run by

   University of Cincinnati

   See if you can join NCT06163482 on ClinicalTrials.gov

3. Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

   The STOP PEDS RCT is a multicenter, parallel, open label randomized controlled trial evaluating the long-term (one year) and short-term safety and efficacy of two antibiotic treatment strategies for the management of outpatient pulmonary exacerbations (PEx) in the pediatric CF population.

   Stage

   Not phased

   Ages

   3 to 18

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   33 in total

   Run by

   University of Washington, the Collaborative Health Studies Coordinating Center

   See if you can join NCT06654752 on ClinicalTrials.gov

4. Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

   This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children with cystic fibrosis (CF).

   Stage

   Not phased

   Ages

   Up to 10

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   35 in total

   Run by

   Sonya Heltshe

   See if you can join NCT04509050 on ClinicalTrials.gov

5. Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

   The purpose of this study is to look at pulmonary exacerbations in people with cystic fibrosis (CF) that need to be treated with antibiotics given through a tube inserted into a vein (intravenous or IV). A pulmonary exacerbation is a worsening of respiratory symptoms in people with CF that needs me…

   Stage

   Phase 4

   Ages

   6 and older

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   60 in total

   Run by

   Chris Goss

   See if you can join NCT05548283 on ClinicalTrials.gov

6. Regional Monitoring of CF Lung Disease

   The main reason for this research study is to learn more about some new tests that are being developing for patients with Cystic Fibrosis (CF) to measure changes in the lungs. In this study, the focus will be to learn how stopping Airway Clearance (ACT) and re-starting ACT can affect these tests. T…

   Stage

   EARLY_Phase 1

   Ages

   12 to 21

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT06339593 on ClinicalTrials.gov

7. Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials

   The purpose of this study is to validate and utilize a personalized medicine approach to identify potential treatments with current FDA approved CFTR modifiers for non-approved CF gene mutations. The study will perform ex vivo testing of CFTR function and current marketed CFTR modulating drugs on e…

   Stage

   Not phased

   Ages

   6 and older

   Site

   CCHMC, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT04580368 on ClinicalTrials.gov

8. A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

   The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not take CFTR modulators. This data may be used to in…

   Stage

   Not phased

   Ages

   12 and older

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   68 in total

   Run by

   Nicole Hamblett

   See if you can join NCT06504589 on ClinicalTrials.gov

9. Regional Phenotyping of CF and Non-CF Bronchiectasis

   The Investigators propose to study pediatric subjects who are diagnosed with cystic fibrosis (CF) and patients with non-CF bronchiectasis, with the goal of developing markers of CF lung disease severity, progression, and therapy response. The Investigator's central hypothesis is that image-based ma…

   Stage

   Not phased

   Ages

   5 to 100

   Site

   Penny New, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT04793867 on ClinicalTrials.gov

10. BEGIN Novel ImagiNG Biomarkers

    To determine the treatment effect of triple-combination therapy in 6-8 year olds after presumed FDA approval, using rapid structural and functional pulmonary and abdominal MRI (UTE and 129Xe).

    Stage

    Phase 4

    Ages

    6 to 8

    Site

    Carrie Stevens, Cincinnati, Ohio

    Locations

    3 in total

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT05517655 on ClinicalTrials.gov