Coronary Artery Disease Clinical Trials in Jacksonville, Florida

11 studies are recruiting for coronary artery disease in Jacksonville, Florida right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Product Surveillance Registry

    The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies, payers, and industry by str…

    Stage
    Not phased
    Ages
    Any age
    Site
    Research site, Jacksonville, Florida
    Locations
    401 in total
    Run by
    Medtronic
  2. Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

    Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiate…

    Stage
    Not phased
    Ages
    Any age
    Site
    Memorial Hospital, Jacksonville, Florida
    Locations
    48 in total
    Run by
    Minneapolis Heart Institute Foundation
  3. SELUTION 4 De Novo Small Vessel IDE Trial

    Prospective, randomized controlled, single-blind, multicenter, clinical trial to demonstrate the safety and efficacy of the SELUTION SLR 014 PTCA DEB for treatment of de novo lesions in small coronary vessels, defined as reference vessel diameter (RVD) of 2.00 mm to 2.75 mm, in support of a pre-mar…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Florida, Jacksonville, Jacksonville, Florida
    Locations
    70 in total
    Run by
    M.A. Med Alliance S.A.
  4. Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study

    Dual antiplatelet therapy (DAPT) with low-dose aspirin and a P2Y12 inhibitor is the current standard of care in patients with coronary artery disease experiencing an acute event or undergoing percutaneous coronary intervention. However, the ischemic benefits are counterbalanced by a significant inc…

    Stage
    Phase 4
    Ages
    18 and older
    Site
    University of Florida, Jacksonville, Florida
    Run by
    University of Florida
  5. Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI

    Two strategies have both proven to be effective in reducing bleeding complications while preserving efficacy compared with maintaining long-term DAPT with aspirin and a potent P2Y12 inhibitor: a) DAPT de-escalation (i.e., switching from prasugrel or ticagrelor to clopidogrel while maintaining aspir…

    Stage
    Phase 4
    Ages
    18 and older
    Site
    University of Florida, Jacksonville, Florida
    Run by
    University of Florida
  6. Effects of Low-dose Ticagrelor vs. Clopidogrel in Stable Patients Undergoing Elective Percutaneous Coronary Intervention

    The proposed study aims to assess the antiplatelet effects of more potent oral P2Y12 inhibition with low-dose ticagrelor (60 mg bid) compared with standard of care clopidogrel in patients with a high ABCD-GENE score (≥10). We hypothesize that ticagrelor is associated with better pharmacodynamic eff…

    Stage
    Phase 4
    Ages
    18 and older
    Site
    University of Florida Jacksonville, Jacksonville, Florida
    Run by
    University of Florida
  7. Switching From Dual Antiplatelet Therapy to Monotherapy With Potent P2Y12 Inhibitors

    Ticagrelor currently represents the most tested and commonly used P2Y12 inhibitor monotherapy following percutaneous coronary intervention. The purpose of this study is to conduct a head-to-head comparison on the pharmacodynamic efficacy of ticagrelor-based and prasugrel-based single antiplatelet t…

    Stage
    Phase 4
    Ages
    18 to 75
    Site
    University of Florida Jacksonville, Jacksonville, Florida
    Run by
    University of Florida
  8. A Precision Medicine Approach to Identify Patients Undergoing Elective PCI at Risk of Peri-PCI Myocardial Infarction

    Despite the relative safety of PCI with new generation stents, peri-PCI thrombotic complications, including myocardial infarction and myocardial injury, are common in elective PCI, occurring in up to 30% of patients. Importantly, these events are associated with poor prognosis. The risk of peri-PCI…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Florida Jacksonville, Jacksonville, Florida
    Run by
    University of Florida
  9. MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

    This is a multicenter, randomized, single-blind pivotal study to evaluate the safety and efficacy of the MagicTouchTM Drug coated balloon in treatment of small vessels in patients with coronary artery disease. The objective is to establish the safety and efficacy of the Magic TouchTM Drug coated ba…

    Stage
    Not phased
    Ages
    18 to 80
    Site
    University of Florida Health Sciences Center-Jacksonville, Jacksonville, Florida
    Locations
    24 in total
    Run by
    Concept Medical Inc.
  10. Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

    Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty about the benefits and the optimal timing of revascularization for such patients. There is currently clinical equipoise r…

    Stage
    Not phased
    Ages
    Any age
    Site
    Baptist Health Jacksonville, Jacksonville, Florida
    Locations
    72 in total
    Run by
    University of British Columbia
  11. PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

    This purpose of this trial is to demonstrate 30 day safety and effectiveness outcomes of the KARDION CORY P4 System in subjects who require hemodynamic support during a high-risk PCI procedure.

    Stage
    Not phased
    Ages
    18 to 90
    Site
    Ascension St. Vincent's, Jacksonville, Florida
    Locations
    18 in total
    Run by
    Kardion Inc

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.