Coronary Artery Disease Clinical Trials in Boston, Massachusetts

16 studies are recruiting for coronary artery disease in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Product Surveillance Registry

    The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies, payers, and industry by str…

    Stage
    Not phased
    Ages
    Any age
    Site
    Research site, Boston, Massachusetts
    Locations
    401 in total
    Run by
    Medtronic

    See if you can join NCT01524276 on ClinicalTrials.gov

  2. Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.

    This is a two-part study, comprised of an initial open-label run-in phase (Part 1) in a subset of 3 subjects to provide first data regarding safety, and feasibility of the percutaneous endovascular catheter-facilitated intramyocardial delivery of XC001 in patients with RA due to obstructive CAD. Pa…

    Stage
    Phase 2
    Ages
    18 to 85
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    14 in total
    Run by
    XyloCor Therapeutics, Inc.

    See if you can join NCT07048808 on ClinicalTrials.gov

  3. REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women

    This is a research study in women to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented with a small wire mesh tube through a small incision in the wrist or the groin. The other procedure is an o…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    18 in total
    Run by
    Weill Medical College of Cornell University

    See if you can join NCT06399692 on ClinicalTrials.gov

  4. REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

    This is a research study in minorities to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented with a small wire mesh tube through a small incision in the wrist or the groin. The other procedure is…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    18 in total
    Run by
    Weill Medical College of Cornell University

    See if you can join NCT06399705 on ClinicalTrials.gov

  5. A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)

    The OPTIMAL randomized clinical trial has been designed to compare two imaging strategies and to test the hypothesis that a calcium modification strategy informed by coronary CT angiography (CCTA) will improve procedural efficiency and effectiveness compared with the current standard of care (IVUS-…

    Stage
    Not phased
    Ages
    18 to 85
    Site
    Bringham and Women's Hospital, Boston, Massachusetts
    Locations
    14 in total
    Run by
    Fundación EPIC

    See if you can join NCT07286578 on ClinicalTrials.gov

  6. Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

    Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiate…

    Stage
    Not phased
    Ages
    Any age
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    48 in total
    Run by
    Minneapolis Heart Institute Foundation

    See if you can join NCT02061436 on ClinicalTrials.gov

  7. Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

    The purpose of the study is to assess the safety and efficacy of the Orsiro® Mission 48- mm Sirolimus-Eluting Coronary Stent System in the treatment of subjects with atherosclerotic lesion(s) >36 mm and ≤ 44 mm in length (by visual estimate) in the native coronary arteries with a reference vessel d…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    23 in total
    Run by
    Teleflex

    See if you can join NCT06779630 on ClinicalTrials.gov

  8. SELUTION 4 De Novo Small Vessel IDE Trial

    Prospective, randomized controlled, single-blind, multicenter, clinical trial to demonstrate the safety and efficacy of the SELUTION SLR 014 PTCA DEB for treatment of de novo lesions in small coronary vessels, defined as reference vessel diameter (RVD) of 2.00 mm to 2.75 mm, in support of a pre-mar…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Beth Israel Deaconess, Boston, Massachusetts
    Locations
    70 in total
    Run by
    M.A. Med Alliance S.A.

    See if you can join NCT05946629 on ClinicalTrials.gov

  9. ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

    The primary objective of this protocol is to develop a comprehensive, multicenter international prospective registry to capture long-term clinical outcomes for adult patients undergoing percutaneous coronary intervention (PCI) with drug-coated balloons (DCB) for de novo coronary artery disease.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Tufts Medical Center, Boston, Massachusetts
    Locations
    19 in total
    Run by
    Emory University

    See if you can join NCT07559903 on ClinicalTrials.gov

  10. Physiological Assessment of Severe Coronary Stenosis for Informing Planned PCI

    Traditionally, the severity of a blockage (stenosis) in a coronary artery has been determined by visual angiographic assessment of the diameter of the artery at the level of a blockage compared to a normal healthy area of the same artery. With the advent of invasive physiological testing to assess …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Beth Israel Deaconess Medical Center, Boston, Massachusetts
    Run by
    Beth Israel Deaconess Medical Center

    See if you can join NCT05491668 on ClinicalTrials.gov

  11. CTSN Embolic Protection Trial

    This is a prospective, multi-center, randomized effectiveness trial of the CardioGard Embolic Protection Cannula in high-risk valve surgery patients.

    Stage
    Not phased
    Ages
    60 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    28 in total
    Run by
    Icahn School of Medicine at Mount Sinai

    See if you can join NCT06027788 on ClinicalTrials.gov

  12. Impact of Disclosing Coronary Artery Disease Polygenic Risk Score on Cardiovascular Health

    The goal of this clinical trial is to evaluate whether disclosure of a polygenic risk score for coronary artery disease (CAD PRS) influences cardiovascular health and risk factor modification over one year among adults aged 30-75 years in the Mass General Brigham primary care network who are not cu…

    Stage
    Not phased
    Ages
    30 to 75
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT07087431 on ClinicalTrials.gov

  13. AI Detection of Incidental Coronary Artery Calcium to Enhance Cardiovascular Disease Prevention

    AI INFORM is a multicenter randomized trial that will test the hypothesis that providing clinicians information on the presence and amount of coronary artery calcifications (CAC), will result in initiation or intensification of preventive therapies. The study will use a cloud-based artificial intel…

    Stage
    Not phased
    Ages
    40 to 75
    Site
    Brigham and Women's Hospital, Boston, Massachusetts
    Run by
    Brigham and Women's Hospital

    See if you can join NCT06235112 on ClinicalTrials.gov

  14. Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

    Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty about the benefits and the optimal timing of revascularization for such patients. There is currently clinical equipoise r…

    Stage
    Not phased
    Ages
    Any age
    Site
    Tufts Medical, Boston, Massachusetts
    Locations
    72 in total
    Run by
    University of British Columbia

    See if you can join NCT04634240 on ClinicalTrials.gov

  15. PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm

    This purpose of this trial is to demonstrate 30 day safety and effectiveness outcomes of the KARDION CORY P4 System in subjects who require hemodynamic support during a high-risk PCI procedure.

    Stage
    Not phased
    Ages
    18 to 90
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    18 in total
    Run by
    Kardion Inc

    See if you can join NCT06445608 on ClinicalTrials.gov

  16. MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

    A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Superiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus- Coated Balloon in the Treatment of Coronary Drug-Eluting Stent In-Stent Restenosis. Subjects with prior DES implantation presenting with ISR lesions unde…

    Stage
    Not phased
    Ages
    18 to 110
    Site
    Beth Israel Deaconess Medical Center, Boston, Massachusetts
    Locations
    28 in total
    Run by
    Concept Medical Inc.

    See if you can join NCT05908331 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.