COPD Clinical Trials in Birmingham, Alabama

6 studies are recruiting for copd in Birmingham, Alabama right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

   The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with hypoxemia/respiratory distress.

   Stage

   Not phased

   Ages

   22 and older

   Site

   The University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   4 in total

   Run by

   Fisher and Paykel Healthcare

   See if you can join NCT07222410 on ClinicalTrials.gov

2. Effect of Ensifentrine on Sputum Markers of Inflammation in COPD

   This is a randomized, double-blind, placebo-controlled, two-period cross-over study of nebulized ensifentrine (3 mg) or placebo administered BID for two 8-week Treatment Periods. All participants with receive both ensifentrine and placebo during participation. There are 7 in-clinic visits over a to…

   Stage

   Phase 2

   Ages

   40 to 80

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   3 in total

   Run by

   Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

   See if you can join NCT05270525 on ClinicalTrials.gov

3. Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

   The dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care. The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System in the treatment of COPD.

   Stage

   Not phased

   Ages

   40 to 80

   Site

   University of Alabama-Birmingham Hospital - UAB Lung Health Center, Birmingham, Alabama

   Locations

   10 in total

   Run by

   Nuvaira, Inc.

   See if you can join NCT07051707 on ClinicalTrials.gov

4. Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

   The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphysema suffering from dyspnea due to hyperinflation despite optimal medical treatment. The Apreo BREAT…

   Stage

   Not phased

   Ages

   40 to 84

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   22 in total

   Run by

   Apreo Health, Inc.

   See if you can join NCT06891755 on ClinicalTrials.gov

5. Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency

   The goal of this study is to learn whether patients who have a genetic mutation in the genes that cause alpha 1 antitrypsin deficiency also have genetic variation in nearby genes that can increase risk for reduced immune function and respiratory infections. To investigate this hypothesis, we will c…

   Stage

   Phase 4

   Ages

   19 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT07135427 on ClinicalTrials.gov

6. myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

   Parallel-group, prospective, randomized, controlled phase III trial of home High flow Nasal Therapy (HFNT) via myAirvo 3 plus usual COPD medical care vs. usual COPD medical care, for at least 1 year and up to two years in 642 GOLD Grade D, Stages II-IV patients with moderate to very severe COPD at …

   Stage

   Not phased

   Ages

   30 and older

   Site

   UAB School of Medicine/Lung Health Center, Birmingham, Alabama

   Locations

   27 in total

   Run by

   Temple University

   See if you can join NCT05204888 on ClinicalTrials.gov