Congenital Heart Disease Clinical Trials

36 studies are recruiting for congenital heart disease in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Improving Congenital Heart Disease Care

   The theory-informed digital health intervention, called as "Empower My Congenital Health (EmpowerMyCH)" aims to activate and engage ACHD patients in building confidence toward navigating the adult healthcare system. This tool is built after incorporating the theories of behavior change, gathering i…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT06581484 on ClinicalTrials.gov

2. Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery

   The goal of this proposal is to prospectively collect data from a series of 200 patients (all ages) undergoing complex cardiac surgical procedures involving cardiopulmonary bypass (CPB) to: 1. Measure the number of blood activated circulating monocytes before, during and after cardiac surgery and s…

   Stage

   Not phased

   Ages

   Any age

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT04299828 on ClinicalTrials.gov

3. Ventripoint Single Ventricle Study

   This study will validate a coordinate-based 3-dimensional echocardiographic technique for the assessment of cardiac size and function in children and young adults with functional single ventricles.

   Stage

   Not phased

   Ages

   Any age

   Site

   Duke University, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT05262907 on ClinicalTrials.gov

4. Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment

   The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators …

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Florida, Gainesville, Florida

   Locations

   5 in total

   Run by

   Columbia University

   See if you can join NCT03891160 on ClinicalTrials.gov

5. The Co-Op @ HeartWorks

   This protocol is a research study involving human subjects diagnosed with Congenital Heart Defects/Disease (CHD). The Co-Op @ HeartWorks is a cooperative between the research platform at HeartWorks and members of the CHD community. Individuals choosing to participate will be referred to as 'members…

   Stage

   Not phased

   Ages

   0 and older

   Site

   HeartWorks, Inc., Rochester, Minnesota

   Run by

   HeartWorks, Inc.

   See if you can join NCT06469918 on ClinicalTrials.gov

6. Effect of Sacubitril-Valsartan on Cardiac Structure and Function

   The purpose of this study is to compare changes in cardiac structure and function, biomarkers, and patient reported outcomes between adults with congenital heart disease (ACHD) randomized to angiotensin receptor-neprilysin inhibitor (ARNI) therapy vs placebo.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT06693674 on ClinicalTrials.gov

7. Parent Navigator Program (PNP) to Improve Outcomes in Latino/x Children and Parents

   The goal of this clinical trial is to see if a Parent Navigator Program (PNP) is helpful for Latino/x parents of babies with congenital heart disease (CHD) to get connected to developmental follow-up services. The main question it aims to answer are: * Do families assigned to the Parent Navigator P…

   Stage

   Not phased

   Ages

   0 and older

   Site

   Children's Hospital Los Angeles, Los Angeles, California

   Run by

   Children's Hospital Los Angeles

   See if you can join NCT07023367 on ClinicalTrials.gov

8. Effect of Fetal Aortic Valvuloplasty on Outcomes

   In one of the most severe congenital heart defects, hypoplastic left heart syndrome (HLHS), the left ventricle is underdeveloped and the prognosis is worse than in most other heart defects. The underdevelopment can occur gradually during fetal growth caused by a narrowing of the aortic valve. At so…

   Stage

   Not phased

   Ages

   0 to 0

   Site

   Fetal Cardiovascular Program, University of California San Francisco, San Francisco, California

   Locations

   13 in total

   Run by

   Queen Silvia Children's Hospital, Gothenburg, Sweden

   See if you can join NCT05386173 on ClinicalTrials.gov

9. IPSC Repository of Pediatric Cardiovascular Disease

   Obtain blood samples for generation and maintenance of induced pluripotent stem cells (iPSCs) and genomic/DNA sequencing for biomedical research that will improve the understanding and treatment of pediatric cardiovascular disease

   Stage

   Not phased

   Ages

   Any age

   Site

   Nationwide Children's Hospital, Columbus, Ohio

   Run by

   Mingtao Zhao

   See if you can join NCT05550324 on ClinicalTrials.gov

10. Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease

    In this research study the investigators want to learn more about how well the investigators can visualize scar tissue in the heart by MRI. In patients with congenital heart disease who need a procedure in the electrophysiology laboratory, how the MRI findings match the findings in the electrophysi…

    Stage

    Not phased

    Ages

    13 and older

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Run by

    Boston Children's Hospital

    See if you can join NCT05241418 on ClinicalTrials.gov

11. The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study

    This study is enrolling pregnant persons treated at Rady Children's Hospital fetal cardiology program with a prenatal diagnosis of congenital heart disease to look for genetic disorders in the fetus or unborn baby. Congenital heart disease (CHD) is a group of structural differences to the heart tha…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rady Children's Institute for Genomic Medicine, San Diego, California

    Run by

    Scripps Translational Science Institute

    See if you can join NCT06244940 on ClinicalTrials.gov