Chronic Pain Clinical Trials in Durham, North Carolina

4 studies are recruiting for chronic pain in Durham, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Neuroimaging of Opioid Phase (OPAL)

   The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Duke University Medical Center, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT05905419 on ClinicalTrials.gov

2. Predictors of Pain in Sickle Cell Disease

   Sickle cell disease is a painful inherited disorder that affects approximately 100,000 people in the United States, and more than half of these individuals develop chronic or persistent pain that is often severe and disabling. The factors that predict whether an individual with sickle cell disease …

   Stage

   Not phased

   Ages

   15 to 40

   Site

   Duke University Medical Center, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06139510 on ClinicalTrials.gov

3. Opioids, Low Nicotine Cigarettes, and Chronic Pain

   The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain who smoke cigarettes daily and are attending office-based buprenorphi…

   Stage

   Not phased

   Ages

   21 and older

   Site

   North Pavilion, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06747871 on ClinicalTrials.gov

4. Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

   Individuals with chronic pain are more likely to smoke cigarettes and have more difficulty quitting smoking than the general population, in part because withdrawal from smoking can lead to temporary increases in pain. This research will examine how smoking withdrawal changes the way the brain proce…

   Stage

   Not phased

   Ages

   21 to 65

   Site

   Duke North Pavilion, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06983678 on ClinicalTrials.gov