Chronic Obstructive Pulmonary Disease Clinical Trials in Boston, Massachusetts

4 studies are recruiting for chronic obstructive pulmonary disease in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

   LPS18583 is a multinational, randomized, double-blind, placebo-controlled, parallel-group, Phase 4 study with 2 treatment groups. The purpose of this study is to assess the effect of dupilumab compared with placebo on airway inflammation, resistance, and remodeling including mucus plugging and its …

   Stage

   Phase 4

   Ages

   40 to 85

   Site

   Brigham & Women's Hospital- Site Number : 8400014, Boston, Massachusetts

   Locations

   85 in total

   Run by

   Sanofi

   See if you can join NCT07053423 on ClinicalTrials.gov

2. Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

   This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive) with inadequately controlled Chronic obstructive pulmonary disease (COP…

   Stage

   Phase 3

   Ages

   40 to 80

   Site

   Brigham & Women's Hospital- Site Number : 8400148, Boston, Massachusetts

   Locations

   314 in total

   Run by

   Sanofi

   See if you can join NCT07190209 on ClinicalTrials.gov

3. Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

   The goal of this fully-remote randomized controlled trial is to test the efficacy of Mindful Steps in facilitating physical activity compared to usual standard of care among 136 patients with COPD and/or HF. The main question it aims to answer is can this intervention promote physical activity as m…

   Stage

   Not phased

   Ages

   40 and older

   Site

   VA Boston, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Beth Israel Deaconess Medical Center

   See if you can join NCT05934565 on ClinicalTrials.gov

4. Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

   The investigators will study whether the drug tadalafil improves shortness of breath in 126 Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs. The investigators will also assess whether tadalafil improves quality of life, home daily physical activity, e…

   Stage

   Phase 2

   Ages

   35 to 89

   Site

   VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts

   Locations

   5 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT05937854 on ClinicalTrials.gov