Cervical Cancer Clinical Trials

75 studies are recruiting for cervical cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. Self-Collection of the Pap Smear as Agency: A Novel Way to Improve Refractory Low Cervical Cancer Screening Rates in Rural Alabama

   The purpose of the study is to find out if a self-administered (by the patient) Papanicolaou (Pap) smear is as accurate as a traditional Pap smear administered by a healthcare provider.

   Stage

   Not phased

   Ages

   21 to 65

   Site

   Cahaba Medical Care - West End, Birmingham, Alabama

   Locations

   3 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT04093388 on ClinicalTrials.gov

2. 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

   A Phase 1/2a Dose Escalation and Expansion Study of the Safety, Tolerability, and Preliminary Clinical Activity of 177LuBetaBart, a 177Lu-Labeled Anti-B7-H3 Monoclonal Antibody, in Patients with Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Dothan Hematology & Oncology, Dothan, Alabama

   Locations

   4 in total

   Run by

   Radiopharm Theranostics, Ltd

   See if you can join NCT07189871 on ClinicalTrials.gov

3. Cervical Cancer Detection Using Optical Spectroscopy

   The objective of the work described in this protocol is to determine the optical signatures of cervical dysplasia using optical technologies.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Duke University Medical Center, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT00900575 on ClinicalTrials.gov

4. Pilot Study for Speculum Free Cervical Cancer Screening

   The objective of the work described in this protocol is to determine the optical signatures of cervical dysplasia using optical technologies.

   Stage

   Not phased

   Ages

   21 to 65

   Site

   Duke University, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT04107181 on ClinicalTrials.gov

5. Detecting HPV DNA in Anal and Cervical Cancers

   This is a research study for individuals who have cancer associated with human papillomavirus (HPV) and are being treated with radiation as part of standard care for their cancer. Doctors leading this study will use blood tests to find out if they can detect the HPV virus in the blood of study part…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Illinois at Chicago, Chicago, Illinois

   Locations

   2 in total

   Run by

   University of Chicago

   See if you can join NCT04857528 on ClinicalTrials.gov

6. Using Plasma Human Papillomavirus (HPV)-Related Deoxyribonucleic Acid (DNA) and Ribonucleic Acid (RNA) to Follow Response of Cervical Cancer to Surgery, Radiation, and Chemotherapy

   The goal of this study is to test two commercially available technologies for their ability to detect treatment response in patients with cervical cancer following surgery, radiation, and chemotherapy: one based on polymerase chain reaction (PCR; NavDx) and the other on branched DNA (Quantivirus HP…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT07214584 on ClinicalTrials.gov

7. ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services

   While there has been a significant increase in the uptake of antiretroviral therapy among women living with HIV (WLHIV) in many low- and-middle income countries (LMICs), the coverage of cervical cancer screening and treatment (CCST) among WLHIV remains low. This study aims to leverage the available…

   Stage

   Not phased

   Ages

   25 to 64

   Site

   UC San Diego, La Jolla, California

   Locations

   2 in total

   Run by

   University of California, San Diego

   See if you can join NCT06128304 on ClinicalTrials.gov

8. Improving Care for Rural Patients With Solid Tumors

   This study will assess if the CARES (Cancer Advocacy, Resources, Education and Support) intervention improves time to start of treatment after diagnosis and time to treatment completion for solid tumors (ex: lung, head, neck, thyroid, cervical, breast, bladder, colon, and rectal cancers) in rural p…

   Stage

   Not phased

   Ages

   18 to 99

   Site

   University of Colorado Hospital, Aurora, Colorado

   Locations

   14 in total

   Run by

   University of Colorado, Denver

   See if you can join NCT04916990 on ClinicalTrials.gov

9. Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

   The objective of this study is to evaluate the safety, tolerability, and efficacy of BL-B01D1 in patients with Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Beverly Hills Cancer Center, Beverly Hills, California

   Locations

   39 in total

   Run by

   SystImmune Inc.

   See if you can join NCT05983432 on ClinicalTrials.gov

10. cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

    This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types. The cancers included in this study are brain, breast, bladder, cervical, colorectal, endometrial, esophageal, gast…

    Stage

    Not phased

    Ages

    40 and older

    Site

    City of Hope, Duarte, California

    Locations

    17 in total

    Run by

    Adela, Inc

    See if you can join NCT05366881 on ClinicalTrials.gov

11. A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

    A phase 1a/1b, multicenter, open-label, dose escalation/expansion, multiple-dose study to evaluate the safety and activity of DR-0202 in patients with locally advanced or metastatic, relapsed or refractory carcinomas

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Dren Investigational Site, Denver, Colorado

    Locations

    10 in total

    Run by

    Dren Bio

    See if you can join NCT06999187 on ClinicalTrials.gov

12. Image-Guided Gynecologic Brachytherapy

    This research is being done to evaluate multimodality imaging, including magnetic resonance imaging-guided therapy (MRT), as a possible treatment for gynecologic cancers. The therapy takes place in the Department of Radiation Oncology at the Johns Hopkins SKCCC. The purpose of this study is to inve…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    The SKCCC at Johns Hopkins, Baltimore, Maryland

    Run by

    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    See if you can join NCT02993900 on ClinicalTrials.gov

13. A Study of MT-4561 in Patients With Various Advanced Solid Tumors

    This is a First In Human (FIH), multicenter, open-label, Phase I/II study to evaluate safety, tolerability, Pharmacokinetics (PK), pharmacodynamics, and efficacy of MT-4561 in patients with advanced solid tumors. This study will be conducted in 3 parts. Part 1 is aimed at evaluating safety, tolerab…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    University of Southern California, Los Angeles, California

    Locations

    6 in total

    Run by

    Tanabe Pharma America, Inc.

    See if you can join NCT06943521 on ClinicalTrials.gov

14. Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin

    The purpose of this research study is to see if the study drug Belzutifan is effective and safe for participants with clear cell gynecologic malignancy, including but not limited to, ovarian cancer, endometrial cancer, cervical cancer, vaginal cancer, vulvar cancer, or endometriosis-related cancer.…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Dana-Farber Cancer Institute

    See if you can join NCT06677190 on ClinicalTrials.gov

15. A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib

    The purpose of this research is to test the effectiveness and safety of the study drugs (VS-6766 and defactinib), and see what effects (good and bad) these drugs have on the patients with endometrioid cancer, mucinous ovarian cancer, high-grade serous ovarian cancer, or solid gynecological cancer.

    Stage

    Phase 2

    Ages

    18 to 99

    Site

    AdventHealth, Orlando, Florida

    Locations

    4 in total

    Run by

    University of Oklahoma

    See if you can join NCT05512208 on ClinicalTrials.gov

16. Mindfulness in Endometrial and Cervical Cancer

    Patients with endometrial cancer who will be undergoing surgery or patients with cervical cancer who will be treated with chemoradiation will be randomized to utilize the Headspace smartphone application or not prior to their anticipated treatment.

    Stage

    Not phased

    Ages

    18 to 90

    Site

    Saint Louis University, St Louis, Missouri

    Run by

    St. Louis University

    See if you can join NCT04512144 on ClinicalTrials.gov

17. Circulating Human Papilloma Virus (HPV) DNA for the Screening and Surveillance of Gynecologic Cancers

    Human papilloma virus-related gynecologic malignancies affect over 20,000 women in the United States, and over half a million women globally each year. In addition, approximately 200,000 women are diagnosed with high-grade cervical dysplasia, a pre-cancerous tumor. There is no currently available s…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Lenox Hill Hospital, New York, New York

    Run by

    Northwell Health

    See if you can join NCT05606133 on ClinicalTrials.gov

18. A Study of NX-1607 in Adults With Advanced Malignancies

    This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-1607 in patients with advanced malignancies.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    University of Southern California, Los Angeles, California

    Locations

    17 in total

    Run by

    Nurix Therapeutics, Inc.

    See if you can join NCT05107674 on ClinicalTrials.gov

19. Biological Drivers of Cervical Cancer and Side Effects From Radiation Therapy

    The goal of this observational study is to learn more about the biology of cervical cancer in women who receive radiation therapy for this condition. The main question it aims to answer is: Does radiation therapy alter the expression of tissue factor and other molecules in cervical cancer over time…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of California San Diego, La Jolla, California

    Run by

    University of California, San Diego

    See if you can join NCT07121543 on ClinicalTrials.gov

20. FIGO 2018 Stage IB2 Cervical Cancer Treated With Neoadjuvant Chemotherapy Followed by Fertility Sparing Surgery

    This study will include patients with invasive cervical cancer that wish to keep their fertility as much as possible in the future after treatment. Patients who receive surgery alone may experience long-term side effects including infertility. The purpose of this research study is to determine whet…

    Stage

    Not phased

    Ages

    18 to 40

    Site

    Sunnybrook Health Sciences Centre, Toronto, Ontario

    Locations

    4 in total

    Run by

    University Health Network, Toronto

    See if you can join NCT04016389 on ClinicalTrials.gov

21. A Beta-only IL-2 ImmunoTherapY Study

    This is a Phase 1/2, multi-center, open-label, dose-escalation and expansion study to evaluate safety and tolerability, PK, pharmacodynamic, and early signal of anti-tumor activity of MDNA11 alone or in combination with a checkpoint inhibitor in patients with advanced solid tumors.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Sharp Memorial Hospital, San Diego, California

    Locations

    27 in total

    Run by

    Medicenna Therapeutics, Inc.

    See if you can join NCT05086692 on ClinicalTrials.gov

22. A Multicenter Cancer Biospecimen Collection Study

    This study will collect de-identified tumor samples, with correlated clinical/demographic data and tissue histology, from patients selected or scheduled for pre-treatment tumor biopsy or who have had a recent pre-treatment tumor biopsy. These specimens and clinical data may be used in subsequent st…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Curebase, San Francisco, California

    Run by

    Cofactor Genomics, Inc.

    See if you can join NCT04510129 on ClinicalTrials.gov

23. NYSCF Scientific Discovery Biobank

    The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disease research using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and store th…

    Stage

    Not phased

    Ages

    0 and older

    Site

    New York Stem Cell Foundation Research Institute, New York, New York

    Run by

    New York Stem Cell Foundation Research Institute

    See if you can join NCT06203106 on ClinicalTrials.gov

24. Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

    RATIONALE: To improve strategies for detection and prevention of early-stage disease. PURPOSE: This research study is collecting specimens and data to develop better methods for early detection and prevention of ovarian cancer among the high risk population and those who have the disease.

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT00005095 on ClinicalTrials.gov

25. Reducing Urban Cervical Cancer Disparities

    This study uses a hybrid Type 1 effectiveness-implementation trial to operationalize and assess the efficacy of the Health Enhancement Resource System (HERS) intervention. HERS aims to increase patient follow-up after abnormal test results through text message-based barriers counseling for women an…

    Stage

    Not phased

    Ages

    18 to 90

    Site

    Rutgers, The State University of New Jersey, New Brunswick, New Jersey

    Locations

    3 in total

    Run by

    Fox Chase Cancer Center

    See if you can join NCT06416150 on ClinicalTrials.gov