Breast Cancer Clinical Trials

414 studies are recruiting for breast cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 5

1. A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

   The purpose of this study is to evaluate the safety, tolerability, drug levels, and preliminary efficacy of BMS-986507 combinations in adult participants with advanced solid tumors.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   65 in total

   Run by

   Bristol-Myers Squibb

   See if you can join NCT06618287 on ClinicalTrials.gov

2. Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

   This phase 3 clinical trial compares the efficacy and safety of palazestrant with ribociclib to letrozole and ribociclib in women and men who have not received prior systemic anti-cancer treatment for advanced breast cancer.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Clinical Trial Site, Hot Springs, Arkansas

   Locations

   200 in total

   Run by

   Olema Pharmaceuticals, Inc.

   See if you can join NCT07085767 on ClinicalTrials.gov

3. Remotely-Delivered Cognitive Behavioral Stress Management for Breast Cancer (R-CBSM)

   The purpose of this research study to find out if a program called Remotely-delivered Cognitive Behavioral Stress Management (R-CBSM) can help women with breast cancer in the period of survivorship after they have completed treatment. This is a group stress management program done from home using t…

   Stage

   Not phased

   Ages

   50 and older

   Site

   University of Miami, Coral Gables, Florida

   Run by

   University of Miami

   See if you can join NCT07502352 on ClinicalTrials.gov

4. Intra-Operative Radiation Registry

   This registry trial is designed to track the local control rates and side effects of IORT, which will be implemented for women who are suitable partial breast irradiation (PBI) per the latest American Society of Radiation Oncology (ASTRO) guidelines.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Montefiore Medical Center - Moses Campus, The Bronx, New York

   Run by

   Albert Einstein College of Medicine

   See if you can join NCT04994067 on ClinicalTrials.gov

5. ARTIDIS Nanomechanical Generated Measurements for Early Breast Lesions

   This prospective, blinded, single-arm study aims to test the performance of nanomechanical phenotype in predicting tumor type, tumor aggressiveness, and neoadjuvant treatment response compared to the gold standard of histopathological assessment. The study involves patients with suspicious breast l…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Texas Southwestern Medical Center, Dallas, Texas

   Locations

   6 in total

   Run by

   ARTIDIS AG

   See if you can join NCT06085833 on ClinicalTrials.gov

6. Cardiovascular Health Education Via Virtual Reality for Breast Cancer Survivors Receiving Anthracyclines or Trastuzumab

   The main goal of this study is to test a virtual reality (VR) program, Survivors' Virtual Reality Survivorship Experience (SurviVRSE), designed to help Breast Cancer survivors (n=30) learn about heart health. The aims are to test the usability, feasibility, and acceptability o the intervention. Add…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Adult Outpatient Pavilion, Richmond, Virginia

   Locations

   3 in total

   Run by

   Virginia Commonwealth University

   See if you can join NCT07426913 on ClinicalTrials.gov

7. Biopsy-site-marker in Breast Cancer

   The purpose of this study is to explore pro-metastatic changes in breast cancer (BC) associated with the stiffness of biopsy site markers. This study aims to determine whether the stiffness of a biopsy site marker promotes inflammatory changes in breast cancer and to evaluate whether there is a rel…

   Stage

   Not phased

   Ages

   18 and older

   Site

   OU Health Stephenson Cancer Center, Oklahoma City, Oklahoma

   Run by

   University of Oklahoma

   See if you can join NCT07833566 on ClinicalTrials.gov

8. Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

   Most physicians still use a one-size-fits-all approach to breast screening in which all women, regardless of their personal history, family history or genetics (except BReast CAncer gene (BRCA) carriers) are recommended to have annual mammograms starting at age 40. Mammograms benefit women by detec…

   Stage

   Not phased

   Ages

   30 to 74

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   11 in total

   Run by

   University of California, San Francisco

   See if you can join NCT02620852 on ClinicalTrials.gov

9. Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer

   The purpose of this study is to determine if the dose of radiation therapy that is effective in producing a treatment response, delivered over a shorter treatment period, is a safe approach that causes few or mild side effects in women with newly diagnosed breast cancer or DCIS who have had a lumpe…

   Stage

   Phase 2

   Ages

   45 and older

   Site

   Norwalk Hospital, Norwalk, Connecticut

   Locations

   9 in total

   Run by

   Memorial Sloan Kettering Cancer Center

   See if you can join NCT04084730 on ClinicalTrials.gov

10. Magseed Enabled Long-Term Localization of Axillary Lymph Nodes

    The purpose of this study is to provide prospective evidence that the use of Magseed/Sentimag in marking axillary lymph nodes and guiding surgical localization in patients with breast cancer following neo-adjuvant chemotherapy (NAC) is effective.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Baylor Medicine, Houston, Texas

    Locations

    2 in total

    Run by

    Endomagnetics Ltd.

    See if you can join NCT03796559 on ClinicalTrials.gov

11. Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

    This trial studies how well fecal microbiota transplantation works in treating diarrhea or colitis (inflammation of the intestines) that is caused by certain types of medications (called immune-checkpoint inhibitors) in patients with genitourinary cancer. Fecal microbiota transplantation may effect…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    M D Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT04038619 on ClinicalTrials.gov

12. Identifying Patterns in the Breath of Individuals With Breast Cancer

    Researchers will compare the breath profiles of women with breast cancer and those without to determine whether there are disease-specific patterns that can be leveraged to facilitate breast cancer detection. Women with mammogram-confirmed breast tissue density undergoing standard-of-care breast ca…

    Stage

    Not phased

    Ages

    40 to 74

    Site

    GW Comprehensive Breast Center, Washington D.C., District of Columbia

    Locations

    5 in total

    Run by

    Breathe BioMedical Inc

    See if you can join NCT06512350 on ClinicalTrials.gov

13. Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

    This is a multicenter, multi-arm, biomarker-stratified trial designed to evaluate biomarker-directed therapies in patients with estrogen receptor-positive/hormone receptor-negative (ER+/HR-) and triple-negative (TN) metastatic breast cancer (MBC). The trial integrates both retrospective and prospec…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Yale Cancer Center Clinical Trials Office, New Haven, Connecticut

    Locations

    6 in total

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT07340541 on ClinicalTrials.gov

14. Pulsed Electric Field Ablation for Metastatic Breast Cancer

    This is a phase I trial of the safety of image-guided pulsed electric field (PEF) ablation for the locoregional treatment of superficial soft tissue lesions in adults with metastatic breast cancer using the AliyaTM Pulsed Electric Field System.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of California San Francisco, San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT07487844 on ClinicalTrials.gov

15. ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health

    AUDIBLE is a multi-site, clinical study conducted in the United States aimed at gathering data on 3D Automated Breast Ultrasound imaging using the iSono Health ATUSA system. The study focuses on female participants who have previously been identified with suspicious findings (classified as BIRADs 4…

    Stage

    Not phased

    Ages

    18 to 94

    Site

    UC Davis, Sacramento, California

    Locations

    2 in total

    Run by

    iSono Health, Inc.

    See if you can join NCT07505797 on ClinicalTrials.gov

16. Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

    Radiation therapy is an essential treatment for tumors in the chest area, including breast, lung, esophageal, mediastinal cancers, and spine metastases. Although technical advances have reduced treatment-related illness and death, radiation exposure to the heart can still cause substantial rates of…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill, North Carolina

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT07685938 on ClinicalTrials.gov

17. A Study of Breast Cancer Risk Factors and Outcomes of People in Florida

    The purpose of this study is to understand why different people have different risks and outcomes for breast cancer and non-breast cancer.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Miami (Data Collection Only), Miami, Florida

    Locations

    3 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT06780176 on ClinicalTrials.gov

18. Precision Supplemental Imaging in Women With Dense Breasts

    Recent research has shown that, among women with extremely dense breasts and normal results on mammogram, magnetic resonance imaging (MRI) use has significantly reduced the occurrence of breast cancer that is diagnosed during the time between two regular screening mammograms (also known as interval…

    Stage

    Not phased

    Ages

    25 to 55

    Site

    Washington University School of Medicine, St Louis, Missouri

    Run by

    Washington University School of Medicine

    See if you can join NCT07277738 on ClinicalTrials.gov

19. Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer

    The purpose of this study is to examine the effect of probiotics on the breast tumor microbiome and gut microbiome in breast cancer. Microorganisms that make up the microbiome (such as viruses, bacteria, and fungi) may have an important role in breast cancer development. Understanding the associati…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center, Cleveland, Ohio

    Run by

    Case Comprehensive Cancer Center

    See if you can join NCT04362826 on ClinicalTrials.gov

20. A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

    The primary goal of this study is to evaluate the effectiveness of elacestrant versus standard endocrine therapy in participants with node-positive, Estrogen Receptor-positive (ER+), Human Epidermal Growth Factor-2 negative (HER2-) early breast cancer with high risk of recurrence.

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Southern Cancer Center, PC, Daphne, Alabama

    Locations

    567 in total

    Run by

    Stemline Therapeutics, Inc.

    See if you can join NCT06492616 on ClinicalTrials.gov

21. Utility of a Mobile Application for Young Women With Breast Cancer

    This study aims to evaluate the use of mobile technology as a communication tool among patients with breast cancer and measured its effect on patient-reported cancer-related distress, specifically focusing on young women as they often face unique challenges.

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Atrium Health Levine Cancer, Charlotte, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT07009093 on ClinicalTrials.gov

22. Evaluation and Outcomes of SAVI Scout MD for Localized Breast Surgery

    The purpose of the study is to evaluate how precise the SAVI Scout MD is and how easy it is for surgeons to use during surgery. The SAVI Scout MD system uses tiny radar reflectors instead of wires, can be placed days or weeks before surgery, helps surgeons find the cancer more precisely and may low…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Moffitt Cancer Center, Tampa, Florida

    Run by

    H. Lee Moffitt Cancer Center and Research Institute

    See if you can join NCT07686250 on ClinicalTrials.gov

23. A Study of Pembrolizumab and Ablation (Cryoablation or Histotripsy) in People With Breast Cancer

    Participants will have a confirmed diagnosis of metastatic breast cancer and will receive pembrolizumab in combination with ablation (cryoablation or histotripsy) OR pembrolizumab alone. Participants will be randomly assigned.

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Memorial Sloan Kettering Cancer Center at Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey

    Locations

    7 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT06246968 on ClinicalTrials.gov

24. A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery

    The purpose of this study is to find out whether pre-operative mpMRI using additional MRI sequences may improve surgical outcomes by providing more accurate information about the extent and acidity of the tumor than standard MRI, and to see whether the use of the fluorescent imaging agent pHLIP ICG…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Memorial Sloan Kettering Bergen (All Protocol Activities), Montvale, New Jersey

    Locations

    2 in total

    Run by

    Memorial Sloan Kettering Cancer Center

    See if you can join NCT05130801 on ClinicalTrials.gov

25. SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation

    The purpose of SIBYL is to generate clinical validity data for the ability of a future version of Guardant360 developed by Guardant Health to measure response to systemic therapy in patients with unresectable advanced solid tumors. It is necessary to collect clinical data points and treatment outco…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Orchard Healthcare Research Inc., Skokie, Illinois

    Run by

    Guardant Health, Inc.

    See if you can join NCT05935384 on ClinicalTrials.gov