Blood Pressure Clinical Trials

43 studies are recruiting for blood pressure in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)

   This is an 8 to14-week three-arm randomized controlled in children 8 to 12 years old. The main purpose of the study is to evaluate if stevia has benefits for weight control and metabolic function relative to caloric sweeteners, and whether it provides benefits in this regard similar to water.

   Stage

   Not phased

   Ages

   8 to 12

   Site

   Arkansas Children's Nutrition Center, Little Rock, Arkansas

   Locations

   2 in total

   Run by

   Arkansas Children's Hospital Research Institute

   See if you can join NCT05992688 on ClinicalTrials.gov

2. Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers

   People who experience repeated bouts of circadian misalignment, such as shift workers, are at higher risk of cardiovascular disease (CVD) and Type 2 diabetes (T2D) compared to daytime workers. However, the mechanism(s) by which shift work and associated circadian misalignment increase CVD and T2D r…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Colorado State University, Fort Collins, Colorado

   Run by

   Colorado State University

   See if you can join NCT06550115 on ClinicalTrials.gov

3. Preventing Cognitive Decline by Reducing BP Target Trial

   The PCOT study is a multi-site randomized trial of patients 70 years or older with high BP. The main goal of the study Preventing Cognitive Decline by Reducing BP Target Trial (PCOT) is to conduct a large pragmatic clinical trial (PCT) to test the hypothesis that patients who receive care with a co…

   Stage

   Not phased

   Ages

   70 and older

   Site

   UT Southwestern Medical Center, Dallas, Texas

   Run by

   University of Texas Southwestern Medical Center

   See if you can join NCT05106036 on ClinicalTrials.gov

4. Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

   In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that …

   Stage

   Not phased

   Ages

   Up to 17

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT03431064 on ClinicalTrials.gov

5. Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

   Individuals who have insomnia with short sleep duration (ISS) differ from individuals who have insomnia with normal sleep duration (INS) in terms of health risks (i.e., hypertension) and treatment response. This study will examine whether patients with ISS and INS demonstrate a differential respons…

   Stage

   EARLY_Phase 1

   Ages

   18 and older

   Site

   National Jewish Health, Denver, Colorado

   Locations

   4 in total

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT06281756 on ClinicalTrials.gov

6. COVID-19 Health Adjustments in Nutrition, General Wellness, and Exercise

   The purpose of this study is to find out whether the COVID pandemic has affected participants' current physical activity, fitness, blood pressure, sleep, and mental stress to better understand its long-term health effects. To complete this study, participants will visit the Neurovascular Physiology…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Indiana University School of Public Health, Bloomington, Indiana

   Run by

   Indiana University

   See if you can join NCT07128095 on ClinicalTrials.gov

7. A Food As Medicine Approach to Address Food Insecurity in Rural North Carolina

   Increasing fruit and vegetable (FV) intake, and reducing saturated fat, salt, and added sugar are central lifestyle recommendations in the Dietary Guidelines for Americans to prevent chronic disease. Yet, while diet is modifiable, numerous barriers exist for lower-resourced families to engage in he…

   Stage

   Not phased

   Ages

   8 to 64

   Site

   North Carolina State University, Raleigh, North Carolina

   Run by

   North Carolina State University

   See if you can join NCT07221045 on ClinicalTrials.gov

8. Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

   Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having …

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Ohio State University, Columbus, Ohio

   Run by

   Ohio State University

   See if you can join NCT06055036 on ClinicalTrials.gov

9. The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

   This project will investigate the effect of spinal cord transcutaneous stimulation on blood pressure in individuals with a chronic spinal cord injury who experience blood pressure instability, specifically, orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back t…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Kessler Foundation, West Orange, New Jersey

   Run by

   Kessler Foundation

   See if you can join NCT05725499 on ClinicalTrials.gov

10. Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)

    The goal of this clinical trial is to evaluate the effect of transcutaneous spinal cord stimulation on blood pressure in individuals with an acute spinal cord injury (within 30 days of injury). Blood pressure instability, specifically orthostatic hypotension (a drop in blood pressure when moving ly…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    Kessler Foundation, West Orange, New Jersey

    Run by

    Kessler Foundation

    See if you can join NCT05731986 on ClinicalTrials.gov

11. The GUARDIAN Trial

    An international randomized trial to test the primary hypothesis that perioperative tight blood pressure management reduces a composite of major perfusion-related complications (myocardial injury, stroke, non-fatal cardiac arrest, Stage 2-3 acute kidney injury, deep or organ-space infection, sepsis…

    Stage

    Not phased

    Ages

    45 and older

    Site

    MetroHealth Medical Center, Cleveland, Ohio

    Locations

    20 in total

    Run by

    The University of Texas Health Science Center, Houston

    See if you can join NCT04884802 on ClinicalTrials.gov

12. Adapting a Stress Management Intervention to Reduce Cardiovascular Disease Risk

    Women living with HIV have 2-4x higher risk for cardiovascular disease compared to women without HIV, with women living with HIV in the Southern US being particularly at risk. While an increased prevalence of traditional risk factors (e.g., hypertension, diabetes, and obesity) partially explain thi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT06811896 on ClinicalTrials.gov

13. Cocooned Moms Study

    The Cocooned Moms Study is a pre- and post-design study primarily aimed at reducing stress, depressive symptoms, and blood pressure among expectant Black women by providing them with free access to the InovCares mobile app. InovCares is a culturally-sensitive telehealth platform designed for commun…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University Of Miami, Miami, Florida

    Locations

    2 in total

    Run by

    InovCares Connected Comprehensive Healthcare Corporation

    See if you can join NCT06968650 on ClinicalTrials.gov

14. Reversing Glucose and Lipid-mediated Vascular Dysfunction

    The purpose of our study is to understand the extent to which the blood vessels are affected by glucose and fat (lipids) in lean healthy adults and if these changes in the blood vessels contribute to the development of high blood pressure.

    Stage

    EARLY_Phase 1

    Ages

    18 to 79

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT04832009 on ClinicalTrials.gov

15. Mitigating the Pro-inflammatory Phenotype of Obesity

    The purpose of this study is to examine the hypothesize that 4 weeks of sympathetic nerve activity (SNA) inhibition (oral clonidine) will cause a significant reduction in circulating blood concentrations and endothelial cell expression of inflammatory markers (e.g., TNF-α, IL-6). Our study is a pro…

    Stage

    Phase 1

    Ages

    18 to 79

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT04934228 on ClinicalTrials.gov

16. Inspiratory Muscle Strength Training in Chronic Kidney Disease

    More than 80% of individuals with chronic kidney disease have concomitant hypertension and the majority fail to achieve blood pressure control <130/80 mmHg, leading to high risk of cardiovascular diseases and end-stage kidney disease. A stepwise combination of lifestyle modifications and drug thera…

    Stage

    Not phased

    Ages

    50 and older

    Site

    University of Colorado - Anschutz Medical Campus, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT04911491 on ClinicalTrials.gov

17. Potassium, Hydration, Cardiovascular, and Kidney Study (PHACKs)

    Compared with White Adults, Non-Hispanic Black Adults are at an elevated risk of developing cardiovascular disease (CVD) and end stage chronic-kidney disease (CKD), two of the leading causes of death in the United States. Inadequate hydration status is associated with risk factors for both CVD and …

    Stage

    Not phased

    Ages

    18 to 30

    Site

    Kinesiology Building, Auburn, Alabama

    Run by

    Auburn University

    See if you can join NCT06062017 on ClinicalTrials.gov

18. Safety, Feasibility, and Efficacy of TSCS on Stabilizing Blood Pressure for Acute Inpatients With SCI

    Current forms of pharmacologic and non-pharmacologic treatments for hypotension and orthostatic hypotension (OH) remain inadequate during acute inpatient rehabilitation (AIR) following a traumatic spinal cord injury (SCI). A critical need exists for the identification of safe, practical, and effect…

    Stage

    Not phased

    Ages

    14 to 100

    Site

    The Icahn School of Medicine at Mount Sinai, New York, New York

    Run by

    Jill M. Wecht, Ed.D.

    See if you can join NCT06000592 on ClinicalTrials.gov