Blood Pressure Clinical Trials

43 studies are recruiting for blood pressure in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Potatoes, Type 2 Diabetes, and Cardiometabolic Health

   Type 2 diabetes (T2D) is a major chronic health condition which increases risk of coronary artery disease, frailty, cognitive decline, and mortality. Additionally, hypertension is a major comorbidity for individuals with T2D, further increasing the risk of adverse cardiovascular outcomes. The preva…

   Stage

   Not phased

   Ages

   50 to 70

   Site

   Virginia Polytechnic Institute and State University, Blacksburg, Virginia

   Run by

   Virginia Polytechnic Institute and State University

   See if you can join NCT07229482 on ClinicalTrials.gov

2. Multidimensional Sleep Health Intervention for Couples

   The goal of this pilot dyadic study is to adapt a multidimensional sleep health (MDSH) intervention, previously disseminated at the individual level, for relationship partners, determine whether it improves sleep health and aspects of cardiometabolic health, and understand the role of dyadic dynami…

   Stage

   Not phased

   Ages

   30 to 65

   Site

   Columbia University, New York, New York

   Run by

   Columbia University

   See if you can join NCT07603245 on ClinicalTrials.gov

3. TSCS for Acute SCI

   This project will focus on a novel approach to stabilizing blood pressure (BP) during inpatient rehabilitation after acute SCI. After SCI, people have unstable blood pressure, ranging from too low (orthostatic hypotension) to too high (autonomic dysreflexia). Unstable BP often interferes with perfo…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   Mount Sinai Spinal Cord Injury Model System, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT05305118 on ClinicalTrials.gov

4. Ketone Ester And Salt (KEAS) in Older Adults

   Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumpti…

   Stage

   Not phased

   Ages

   50 to 85

   Site

   School of Public Health, Bloomington, Indiana

   Run by

   Indiana University

   See if you can join NCT06868719 on ClinicalTrials.gov

5. Therapeutic Mechanisms of Epidural Spinal Cord Stimulation

   The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions i…

   Stage

   Not phased

   Ages

   18 to 89

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05556902 on ClinicalTrials.gov

6. AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury

   The goal of this clinical trial is to determine if perfusion index (PI) can reliably predict changes in systolic blood pressure (SBP) in persons with spinal cord injury (SCI) during a cool temperature challenge. Participants with SCI can be 18-75 years of age, male or female, neurological level of …

   Stage

   Not phased

   Ages

   18 to 75

   Site

   James J Peters VA Medical Center, The Bronx, New York

   Run by

   James J. Peters Veterans Affairs Medical Center

   See if you can join NCT07699094 on ClinicalTrials.gov

7. Reducing AIR Pollution Exposure to Lower Blood PRESSURE Among New York City Public Housing Residents

   Fine particulate matter <2.5 µm (PM2.5) air pollution is the fifth leading risk factor for global mortality, with the largest portion of deaths due to cardiovascular disease (CVD). While several mechanisms are responsible, PM2.5-induced elevations in blood pressure (BP) may be relevant. Indoor port…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   NYU Langone Health, New York, New York

   Run by

   NYU Langone Health

   See if you can join NCT05874479 on ClinicalTrials.gov

8. Impact of Sleep Restriction on Blood Pressure Reactivity

   The purpose of the research study is to examine the effects of shortened sleep on blood pressure.

   Stage

   Not phased

   Ages

   18 to 45

   Site

   University of Missouri, Columbia, Missouri

   Run by

   University of Missouri-Columbia

   See if you can join NCT07489417 on ClinicalTrials.gov

9. The Venous Distension Reflex and Orthostatic Hypertension

   This research is being done to find out whether distension of veins in legs will cause a rise in blood pressure (orthostatic hypertension).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT03496792 on ClinicalTrials.gov

10. Autonomic Control of the Circulation and VDR

    The study objective of this project is to examine the mechanisms of the venous distension reflex (VDR) in humans. We hypothesize that COX blockade with ketorolac tromethamine, an intravenous NSAID, will attenuate the muscle sympathetic nerve activity (MSNA) response to limb venous distension. To ga…

    Stage

    EARLY_Phase 1

    Ages

    21 to 35

    Site

    Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania

    Run by

    Milton S. Hershey Medical Center

    See if you can join NCT03513770 on ClinicalTrials.gov

11. Personal BP - CAI Study

    A single-center, prospective, observational pilot of the Cerebral Adaptive Index for assessing personalized blood pressure targets

    Stage

    Not phased

    Ages

    45 and older

    Site

    Northwestern University Hospital, Evanston, Illinois

    Run by

    Becton, Dickinson and Company

    See if you can join NCT06492746 on ClinicalTrials.gov

12. The Continuity Study

    A before and after interventional cohort study comparing intermittent blood pressure measurement using the oscillometric arm cuff to continuous noninvasive blood pressure (cNIBP) measurement using the VitaWave finger cuffs in subjects undergoing elective surgery in an outpatient setting.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Rochester Medical Center, Rochester, New York

    Run by

    Becton, Dickinson and Company

    See if you can join NCT07216573 on ClinicalTrials.gov

13. Equol and Vascular Function in Women With Chronic Kidney Disease

    The risk of cardiovascular disease (CVD) is significantly elevated in patients with chronic kidney disease (CKD). Notably, women with CKD commonly experience menstrual disturbances induced by CKD, which may contribute to impaired vascular function and elevated CVD risk. However, most of the literat…

    Stage

    Phase 2

    Ages

    50 and older

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT07194590 on ClinicalTrials.gov

14. Reducing Blood Pressure in Mid-life Adult Binge Drinkers

    This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers. Phase 2 is to examine the effect of 8-week aerobic exercise training on blood pressure, microvascular fu…

    Stage

    Not phased

    Ages

    50 to 64

    Site

    University of Texas at Arlington, Arlington, Texas

    Run by

    The University of Texas at Arlington

    See if you can join NCT05522075 on ClinicalTrials.gov

15. The DREAM Study: A Multidimensional Sleep Health Intervention for Improving Cardiometabolic Health

    The purpose of this randomized clinical trial is to evaluate the impact of a multidimensional sleep health promotion intervention on blood pressure, glycemic control indicators, anthropometric markers of adiposity, and lifestyle factors in adults. Participants will be randomized into an interventio…

    Stage

    Not phased

    Ages

    30 and older

    Site

    Columbia University Irving Medical Center, Mailman School of Public Health, New York, New York

    Run by

    Columbia University

    See if you can join NCT06285968 on ClinicalTrials.gov

16. Enjoying Affordable and Tasty Food Together

    The goal of this pilot study is to examine the feasibility of a novel meal kit and nutrition education intervention among adults aged 40 years and older, who are lower income, and to evaluate the preliminary impact of the meal kit and nutrition education intervention on food insecurity, dietary qua…

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Massachusetts Lowell, Lowell, Massachusetts

    Run by

    University of Massachusetts, Lowell

    See if you can join NCT07036757 on ClinicalTrials.gov

17. The Sleep2BWell Trial

    Improving multiple domains of cardiometabolic health (CMH) through contextual behavioral interventions has the potential to substantially reduce persistent chronic disease disparities. Sleep is critical for preserving CMH and is amenable to intervention in real-world settings. Although sleep health…

    Stage

    Not phased

    Ages

    20 and older

    Site

    Weill Cornell Medicine, New York, New York

    Locations

    2 in total

    Run by

    Columbia University

    See if you can join NCT06565104 on ClinicalTrials.gov

18. Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women

    The goal of this clinical trial is to assess the impact of table grape consumption on gut microbiome, intestinal permeability, systemic inflammation, and vascular function in healthy overweight men and women aged 45-70 years. The main questions it aims to answer are: * Does daily grape intake alter…

    Stage

    Not phased

    Ages

    45 to 70

    Site

    Ragle Human Nutrition Center, Davis, California

    Run by

    University of California, Davis

    See if you can join NCT06544954 on ClinicalTrials.gov

19. Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health

    The purpose of this Phase 1 research study is to answer two questions: (1) How frequent should periods of prolonged sedentary time be interrupted? and (2) What is the appropriate duration or length of time of these breaks in sedentary time? To address these questions, this project will conduct a st…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Center for Behavioral Cardiovascular Health, New York, New York

    Run by

    Columbia University

    See if you can join NCT05353322 on ClinicalTrials.gov

20. IMST for Dementia Risk Reduction

    Using a 2-arm, RCT approach, the primary goal of the study is to evaluate the feasibility and preliminary efficacy of Inspiratory Muscle Strength Training (IMST) as a non-pharmacologic intervention to reduce cardiovascular and cognitive risks in older adults. Next, investigators will examine second…

    Stage

    Not phased

    Ages

    60 to 80

    Site

    Florida State University, Tallahassee, Florida

    Run by

    Florida State University

    See if you can join NCT07349706 on ClinicalTrials.gov

21. PRESSURE CHECK: Find Your Path to Better Health

    This study seeks to develop the evidence for a sustainable, community-partnered, multi-level health system strategy to improve blood pressure control. Two team-based approaches are being tested: 1) a medical model of remote BP management (RBPM) alone, and 2) RBPM plus a social model with a communit…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Yale, New Haven, Connecticut

    Locations

    4 in total

    Run by

    Yale University

    See if you can join NCT06122246 on ClinicalTrials.gov

22. Performance Evaluation of the ViTrack Continuous Non-invasive Blood Pressure Measurement Device

    The purpose of this study is to calibrate the ViTrack™ arterial pressure waveform against intra-arterial pressure (IAP) in dynamic clinical settings and to assess the optimized ViTrack™ design to measure and continuously track blood pressure over a wide, clinically-relevant pressure range.

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Texas Health Science Center at Houston, Houston, Texas

    Run by

    The University of Texas Health Science Center, Houston

    See if you can join NCT06719518 on ClinicalTrials.gov

23. Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

    This multicenter cross-sectional study will include a diverse population of adolescents and adults with CF. The overall Aim is to describe prevalence of diabetes microvascular complications and macrovascular surrogates in people with established CFRD.

    Stage

    Not phased

    Ages

    12 and older

    Site

    University of Colorado Denver, Aurora, Colorado

    Locations

    18 in total

    Run by

    Jaeb Center for Health Research

    See if you can join NCT06837181 on ClinicalTrials.gov

24. Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise

    High blood pressure (BP) is the major modifiable risk factor for cardiovascular diseases (CVD) and related health conditions, particularly among postmenopausal (PM) women. In adults age ≥50 years this risk is primarily driven by above-normal systolic BP (SBP ≥120 mmHg), as diastolic BP plateaus, th…

    Stage

    Not phased

    Ages

    50 and older

    Site

    Integrative Physiology of Aging Laboratory, Boulder, Colorado

    Run by

    University of Colorado, Boulder

    See if you can join NCT05000515 on ClinicalTrials.gov

25. Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women

    This is a cross-sectional study in which the investigators will determine the impact of premature/early menopause on MSNA, BP and baroreflex sensitivity in younger (≤49 yr old) and older (≥50 yr old) women. Specifically, aim one will determine mechanisms driving autonomic dysregulation of BP in pre…

    Stage

    Not phased

    Ages

    35 to 70

    Site

    University of Minnesota, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT04439370 on ClinicalTrials.gov