Autism Clinical Trials

53 studies are recruiting for autism in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Piloting the Competence in Romance and Understanding Sexual Health Curriculum

   The goal of this clinical trial is to learn whether the CRUSH curriculum is possible (feasible), whether it fits the needs of the adults it is designed for (acceptable), and shows initial signs of being helpful (efficacious). CRUSH is a group-based behavioral intervention plus 1-1 coaching designed…

   Stage

   Not phased

   Ages

   18 to 30

   Site

   Boston Children's Hospital, Two Brookline Place, Brookline, Massachusetts

   Run by

   Boston Children's Hospital

   See if you can join NCT07406100 on ClinicalTrials.gov

2. Use of Eye Tracking to Aid in Autism Risk Detection

   The study will use a non-invasive remote eye-tracking system (Eyelink Portable Duo) to acquire a short series of eye-tracking measures.

   Stage

   Not phased

   Ages

   1 to 4

   Site

   Riley Hospital for Children, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT06471504 on ClinicalTrials.gov

3. Testing Conversational Agents as a Digital Companion

   There is a need and opportunity to improve the supports, transitions, and life outcomes of people with autism spectrum disorder. Compared to their neurotypical peers, autistic teenagers and adults report poorer mental health and quality of life and have higher rates of unemployment or underemployme…

   Stage

   Not phased

   Ages

   18 to 35

   Site

   Indiana Institute on Disability and Community, Bloomington, Indiana

   Locations

   3 in total

   Run by

   Friendi.fi Corporation

   See if you can join NCT07533331 on ClinicalTrials.gov

4. Spanish-language Executive Function Intervention for Children With Autism and/or ADHD

   The goal of this clinical trial is to learn whether the Spanish-language version of Unstuck and On Target (SL-Unstuck), an executive functioning (EF) intervention, is feasible, acceptable, and effective for Spanish-speaking caregivers and their neurodivergent children (ages 8-11) in the U.S.. The m…

   Stage

   Not phased

   Ages

   8 to 11

   Site

   University of Colorado Anschutz School of Medicine, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT07084324 on ClinicalTrials.gov

5. Trial of Diphenhydramine for Sleep in Children With Autism

   The purpose of this study is to examine the effect of diphenhydramine on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Diphenhydramine is an anti-histaminergic agent with strong hypnotic properties. To accomplish this, the investigators will use a randomized double-blind pl…

   Stage

   Phase 2

   Ages

   8 to 17

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT05501678 on ClinicalTrials.gov

6. Trial of Zolpidem for Sleep in Children With Autism

   The purpose of this study is to examine the effect of zolpidem on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Zolpidem is a nonbenzodiazepine GABAa receptor agonist drug that acts as a hypnotic. To accomplish this, the investigators will use a randomized double-blind plac…

   Stage

   Phase 2

   Ages

   8 to 17

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT05540574 on ClinicalTrials.gov

7. Trial of Suvorexant for Sleep in Children With Autism

   The purpose of this study is to examine the effect of suvorexant on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Suvorexant is a selective, dual orexin receptor antagonist (DORA) used for the treatment of sleep onset difficulties and/or sleep maintenance. To accomplish thi…

   Stage

   Phase 2

   Ages

   13 to 17

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT05546554 on ClinicalTrials.gov

8. Improving Academic and Social Functioning in Middle-Schoolers With Autism

   The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD). One of the interventions focuses on teaching parents and adolescent skills to help improve their social functioning and the other focuses on teaching parents and a…

   Stage

   Not phased

   Ages

   10 to 15

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT06705907 on ClinicalTrials.gov

9. Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder

   The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavior…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT06859918 on ClinicalTrials.gov

10. SenseToKnow Autism Screening Device Validation Study

    This is a pivotal, prospective, double-blind, study to evaluate the sensitivity and specificity of the SenseToKnow device for the detection of autism spectrum disorder in children 16-36 months of age.

    Stage

    Not phased

    Ages

    1 to 3

    Site

    Duke University, Durham, North Carolina

    Run by

    Duke University

    See if you can join NCT05874466 on ClinicalTrials.gov

11. The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

    The investigators are conducting a 10-week brain imaging and medication study. They are doing the research to study the response of Attention-Deficit/ Hyperactivity Disorder (ADHD) in youth with Autism Spectrum Disorder (ASD) on extended-release formulation of mixed amphetamine salts (MAS) (also kn…

    Stage

    Phase 4

    Ages

    8 to 18

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Gagan Joshi

    See if you can join NCT06853665 on ClinicalTrials.gov

12. Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

    This study will examine the potential effectiveness of a virtually delivered parent-mediated intervention for insistence on sameness behaviors in autism and investigate 1) whether caregivers can learn to deliver the adapted Supportive Parenting for Anxious Childhood emotions (SPACE) intervention fo…

    Stage

    Not phased

    Ages

    6 to 11

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT06472115 on ClinicalTrials.gov

13. The Impact of a Virtual Magic Trick Training Program

    The proposed project will attempt to confirm the benefits of a structured magic trick training program (MTTP) experience in adolescents with autism. Benefits of participating in a 6-week virtual MTTP will be evaluated using validated assessments to measure social-emotional competencies.

    Stage

    Phase 2

    Ages

    11 to 18

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT05664841 on ClinicalTrials.gov

14. Optimizing Outcomes for Young Autistic Children

    The overarching goal of the proposed study is to: (a) determine how best to sequence two parent-mediated interventions: a social communication intervention (Project ImPACT, Improving Parents as Communication Teachers) and a disruptive behavior intervention (Parent Training for Disruptive Behavior) …

    Stage

    Phase 2

    Ages

    1 to 4

    Site

    Northwestern University, Evanston, Illinois

    Run by

    Northwestern University

    See if you can join NCT05926687 on ClinicalTrials.gov

15. "Opt-In" Early Intervention Program for Children Waiting to Receive an Autism Diagnosis

    A growing body of literature documents the benefits of parent-mediated interventions for autism starting early in life . However, the median age of diagnosis in the US continues to be 49 months. Even following formal diagnosis, services often do not begin for another 9 months on average. Such harmf…

    Stage

    Not phased

    Ages

    1 to 4

    Site

    A.J. Drexel Autism Institute, Philadelphia, Pennsylvania

    Run by

    Drexel University

    See if you can join NCT07081724 on ClinicalTrials.gov

16. The FBRI VTC Neuromotor Research Clinic

    The FBRI VTC Neuromotor Research Clinic was established and opened in May of 2013 to provide intensive therapeutic services to individuals with motor impairment secondary to neuromotor disorders. It is direct by Dr. Stephanie DeLuca and based on the principles surrounding ACQUIREc Therapy. ACQUIREc…

    Stage

    Not phased

    Ages

    0 to 18

    Site

    Fralin Biomedical Research Institute - VTC, Roanoke, Virginia

    Run by

    Virginia Polytechnic Institute and State University

    See if you can join NCT03325946 on ClinicalTrials.gov

17. Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care

    Subjects are enrolled in pairs. Pairs consist of an autistic adult age 18-36 and a non-autistic learning partner who has a relationship with the autistic adult, such as a parent. The autistic adult in each pair receives the first stage of Kairon's online leadership training consisting of emotional …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Training is all online and is available to participate in the study from anywhere in the US, run from a site in PA, Wexford, Pennsylvania

    Run by

    Kairon Connect, PBC

    See if you can join NCT07315867 on ClinicalTrials.gov

18. Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism

    This study tests the effectiveness of the Early Start Denver Model (ESDM) in community agencies that serve young autistic children. The feasibility, usability and acceptability of the model will be explored. Understanding effectiveness of new evidence-based models will increase the quality of autis…

    Stage

    Not phased

    Ages

    1 and older

    Site

    University of California, Davis MIND Institute, Sacramento, California

    Run by

    University of California, Davis

    See if you can join NCT06005285 on ClinicalTrials.gov

19. Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism

    Autism spectrum disorder (ASD) is a very heterogeneous disorder with limited empirically validated behavioral and biological interventions. The goal of this pilot investigation is to apply a biologically-based approach to identify predictors of treatment response in children with ASD who are receiv…

    Stage

    Not phased

    Ages

    2 to 4

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT03583684 on ClinicalTrials.gov

20. Word Learning From Parentese in Autistic Children

    The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are factors that influence the effect of parentese on word learning (Aim 3).

    Stage

    Not phased

    Ages

    1 to 4

    Site

    University of Texas at Dallas, Richardson, Texas

    Run by

    The University of Texas at Dallas

    See if you can join NCT06649916 on ClinicalTrials.gov

21. Cerebellum and Autism: Regional Specialization for Social and Executive Functions

    The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.

    Stage

    Not phased

    Ages

    18 to 35

    Site

    American University, Washington D.C., District of Columbia

    Run by

    American University

    See if you can join NCT05396352 on ClinicalTrials.gov

22. Optimizing Dimensions of Reinforcement

    This study is designed to better understand how certain features of reinforcement affect learning and motivation in individuals with intellectual and developmental disabilities (IDD). Participants will take part in a series of structured teaching sessions that involve simple tasks and reward-based …

    Stage

    Not phased

    Ages

    6 to 17

    Site

    Center for Autism Research, Treatment, and Training, Auburn, Alabama

    Locations

    3 in total

    Run by

    Auburn University

    See if you can join NCT07137273 on ClinicalTrials.gov

23. Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

    Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.

    Stage

    Not phased

    Ages

    12 to 45

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT04532424 on ClinicalTrials.gov

24. Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism

    The purpose of this open label trial is to examine the acceptability, tolerability, and feasibility and preliminary effectiveness of sleep restriction therapy for sleep problems in children with autism spectrum disorder (ASD). Treatment will be delivered via secure telemedicine platform and consist…

    Stage

    Not phased

    Ages

    6 to 12

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT06627205 on ClinicalTrials.gov

25. A Strength-Based Employment Maintenance Program for Individuals on the Autism Spectrum

    The investigators are looking to evaluate how effective a training program that focuses on character strengths may be in improving job maintenance skills in young adults. The investigators are examining the effects of this intervention in young adults who feel they would like to help in improving t…

    Stage

    Not phased

    Ages

    14 to 26

    Site

    Kessler Foundation, East Hanover, New Jersey

    Run by

    Kessler Foundation

    See if you can join NCT06255925 on ClinicalTrials.gov