Autism Clinical Trials

54 studies are recruiting for autism in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. COMPASS Across Settings (CAST) for Improving Transition Outcomes for Students With ASD

   Purpose: The purpose of this project is to develop and test the COMPASS [Collaborative Model for Competence and Success] Across Settings (CAST) intervention to enhance the goal setting and attainment skills of autistic youth. Despite federal education law mandating transition services as part of th…

   Stage

   Not phased

   Ages

   16 to 99

   Site

   Ball State University, Muncie, Indiana

   Run by

   Ball State University

   See if you can join NCT06309160 on ClinicalTrials.gov

2. Word Learning From Parentese in Autistic Children

   The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are factors that influence the effect of parentese on word learning (Aim 3).

   Stage

   Not phased

   Ages

   1 to 4

   Site

   University of Texas at Dallas, Richardson, Texas

   Run by

   The University of Texas at Dallas

   See if you can join NCT06649916 on ClinicalTrials.gov

3. Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for Autism

   This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Autism

   Stage

   Phase 1

   Ages

   Any age

   Site

   Prodromos Stem Cell Institute, Naples, Florida

   Locations

   2 in total

   Run by

   The Foundation for Orthopaedics and Regenerative Medicine

   See if you can join NCT05003960 on ClinicalTrials.gov

4. Improving Academic and Social Functioning in Middle-Schoolers With Autism

   The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD). One of the interventions focuses on teaching parents and adolescent skills to help improve their social functioning and the other focuses on teaching parents and a…

   Stage

   Not phased

   Ages

   10 to 15

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT06705907 on ClinicalTrials.gov

5. To Share or Not To Share: Navigating Disclosure and Stigma Among Family Caregivers of Autistic Young Adults_Group Intervention

   This study is a caregiver support program for family caregivers of autistic young adults (ages 18 to 26) as their family members navigate young adulthood. The program includes six 60-minute virtual sessions focused on making sense of caregiving roles during young adulthood, reflecting on everyday f…

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Wisconsin, Madison, Wisconsin

   Run by

   University of Wisconsin, Madison

   See if you can join NCT07856927 on ClinicalTrials.gov

6. The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

   The purpose of this protocol is to allow for the careful evaluation of healthy volunteers and individuals with risk for psychiatric disorders or neurodevelopmental disorders, such as autism spectrum disorder for specific protocols at NIH.

   Stage

   Not phased

   Ages

   0 and older

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT00271622 on ClinicalTrials.gov

7. Adia Med of Winter Park LLC Autism Spectrum Disorder Research Study

   This 12-month study tests whether AdiaVita (umbilical cord blood-derived stem cells and exosomes) plus glutathione improves autism symptoms more than glutathione alone in children ages 3-12. About 100 children with confirmed autism will be randomly assigned to one of two groups. One group receives …

   Stage

   Phase 1

   Ages

   3 to 12

   Site

   Adia Med Of Winter Park, Winter Park, Florida

   Locations

   2 in total

   Run by

   Adia Med of Winter Park LLC

   See if you can join NCT07304440 on ClinicalTrials.gov

8. Behavioral Activation for Treatment of Depression in Autistic Adolescents With Below Average Intelligence

   Autism spectrum disorder is characterized by differences in social communication/interaction and the presence of restricted/repetitive behaviors, with significant heterogeneity in terms of autistic features, language ability, and cognitive characteristics. About 2-3% of individuals in the United St…

   Stage

   Not phased

   Ages

   12 to 17

   Site

   Stony Brook University, Stony Brook, New York

   Run by

   Stony Brook University

   See if you can join NCT07812870 on ClinicalTrials.gov

9. Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation

   The goal of this study is to help children with autism and a co-occurring intellectual disability and their families learn practical strategies for managing issues like irritability, aggression, and other challenging behaviors. The main objective of this study is: To adapt current Regulating Togeth…

   Stage

   Not phased

   Ages

   8 to 12

   Site

   Children's Mercy, Kansas City, Missouri

   Run by

   Children's Mercy Hospital Kansas City

   See if you can join NCT07624448 on ClinicalTrials.gov

10. Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum Disorder

    The goal of this clinical trial is to learn how prednisone affects adults with autism spectrum disorder (ASD). It will also learn about the safety of prednisone. The main questions it aims to answer are: * How does prednisone affect the core features and associated target symptoms of ASD in adults …

    Stage

    EARLY_Phase 1

    Ages

    18 to 50

    Site

    MGH Lurie Center for Autism, Lexington, Massachusetts

    Run by

    Christopher John McDougle, M.D.

    See if you can join NCT06934915 on ClinicalTrials.gov

11. The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

    The goal of this pilot intervention study is to examine the feasibility and acceptability of a novel bedtime manipulation protocol called "The Power Down" for autistic youth, ages 6-10. The main questions it aims to answer are: 1. Is the Power Down feasible for caregivers to do each night? 2. Do th…

    Stage

    Not phased

    Ages

    6 to 10

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT06386029 on ClinicalTrials.gov

12. Differences in Rest, Emotion, and Arousal Modulation in Youth

    The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10). In a subset of children with elevated sensory responsivity, a sensory-based bedtime manipulation targe…

    Stage

    Not phased

    Ages

    6 to 10

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT07476937 on ClinicalTrials.gov

13. Improving Caregiver Engagement in Early Interventions

    The goal of this study is to test the effectiveness of the FANS-EI program in supporting caregiver engagement in caregiver-mediated early interventions for young children with autism. This study also examines caregiver-perceived social support and self-efficacy and FANS-EI implementation outcomes (…

    Stage

    Not phased

    Ages

    1 and older

    Site

    University of California, Davis MIND Institute, Sacramento, California

    Run by

    University of California, Davis

    See if you can join NCT07500363 on ClinicalTrials.gov

14. Family-Centered Implementation of Parent Training for Autistic Toddlers in Early Intervention

    Early Intervention (EI) systems are ill-equipped to serve the many children 12 to 36 months with early signs or a diagnosis of autism spectrum disorder (ASD). EI funded by Part C of the Individuals with Disabilities Education Act (IDEA) uses home-based service delivery, emphasizes family-centered c…

    Stage

    Not phased

    Ages

    1 to 3

    Site

    University of South Carolina, Columbia, South Carolina

    Run by

    University of South Carolina

    See if you can join NCT07471594 on ClinicalTrials.gov

15. A Toolkit to Improve Mental Health Treatment for Autistic Individuals

    This pilot study is funded by the Organization for Autism Research (OAR). We are conducting a pilot study to improve mental health treatment for autistic individuals. First, we will conduct remote focus groups to identify barriers to mental health treatment and methods to improve treatment. Based o…

    Stage

    Not phased

    Ages

    13 and older

    Site

    Florida International University, Miami, Florida

    Locations

    2 in total

    Run by

    Florida International University

    See if you can join NCT07539519 on ClinicalTrials.gov

16. A Study of Esomeprazole in Children With Autism

    Autism is a pervasive developmental disorder characterized by core deficits in social behavior and communication and the presence of repetitive/stereotyped behaviors. The objective of the study is to evaluate the efficacy of Esomeprazole as a treatment for social communication deficits in children …

    Stage

    Phase 2

    Ages

    2 to 6

    Site

    Stanford University School of Medicine, Stanford, California

    Run by

    Stanford University

    See if you can join NCT03866668 on ClinicalTrials.gov

17. Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth

    The purpose of this open label trial is to examine the preliminary feasibility, acceptability, and effectiveness of a 12-week behavioral intervention program (1 hour/week) to treat insistence on sameness (e.g., difficulty tolerating changes in routine) in youth with autism spectrum disorder (ASD). …

    Stage

    Not phased

    Ages

    4 to 17

    Site

    401 Quarry Road (Remote Study), Stanford, California

    Run by

    Stanford University

    See if you can join NCT06362733 on ClinicalTrials.gov

18. Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

    The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young children with autism spectrum disorder (ASD) with significant language dela…

    Stage

    Not phased

    Ages

    2 to 5

    Site

    Stanford University School of Medicine, Stanford, California

    Run by

    Stanford University

    See if you can join NCT04899544 on ClinicalTrials.gov

19. Early Diagnostic Response Model (EDRM)

    Babies Can't Wait (BCW) in Georgia will be referring families with children seeking an autism spectrum disorder (autism) diagnosis at the Emory Autism Center's (EAC) Child Screening and Assessment Clinic.The objective of this study is to develop, pilot, and evaluate a diagnostic protocol for childr…

    Stage

    Not phased

    Ages

    1 to 3

    Site

    Emory Autism Center, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT05419895 on ClinicalTrials.gov

20. Meeting the Needs of Young Hispanic Autistic Children

    Purpose of the Study: The goal of this clinical trial is to find out if a technique called the "mutual gaze procedure" used in a Culturally and Linguistically Responsive adaptation of Pathways Early Intervention (CLR-Pathways) is the key to improving social communication, language, and everyday ski…

    Stage

    Not phased

    Ages

    1 to 3

    Site

    Catholic Charities of Dallas, Dallas, Texas

    Locations

    3 in total

    Run by

    The University of Texas at Dallas

    See if you can join NCT06733584 on ClinicalTrials.gov

21. Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement

    The goal of this project is to measure the clinical utility of an objective and quantitative eye-tracking assay collected on a standalone, mobile investigational device to accurately screen 9-month-old infants for autism spectrum disorder and other actionable delays.

    Stage

    Not phased

    Ages

    0 to 0

    Site

    Children's Healthcare of Atlanta, Atlanta, Georgia

    Locations

    2 in total

    Run by

    Emory University

    See if you can join NCT05916430 on ClinicalTrials.gov

22. GAIP ASD Research Study

    This clinical research study evaluates the safety and preliminary effects of AdiaVita (umbilical cord blood-derived stem cells and exosomes) combined with glutathione versus glutathione alone in people aged 3 and older with Autism Spectrum Disorder (ASD). In this randomized, participant-blinded cro…

    Stage

    Phase 1

    Ages

    3 and older

    Site

    Greater Atlanta Integrative Pediatrics, Roswell, Georgia

    Locations

    2 in total

    Run by

    Greater Atlanta Integrative Pediatrics

    See if you can join NCT07622316 on ClinicalTrials.gov

23. Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

    The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers. Toddlers receive either Reciprocal Imitation Training (RIT), an evidence-based NDBI that supports children's imitation and s…

    Stage

    Not phased

    Ages

    1 to 3

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT05880225 on ClinicalTrials.gov

24. Online Pivotal Response Treatment Training in Autism Spectrum Disorder

    This is a research study that will assess the effects of a Pivotal Response Treatment Online Training Course (PRT-O) for training parents of children with Autism Spectrum Disorder (ASD). The study will specifically investigate whether participants can learn to deliver PRT effectively following part…

    Stage

    Not phased

    Ages

    2 to 5

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT06523387 on ClinicalTrials.gov

25. Evaluating Georgia Part C Implementation Outcomes

    This study aims to answer the question: What is the best way to help Early Intervention (EI) providers deliver high-quality services to children with communication delays for autism? The primary goal of this project is to examine the outcomes associated with delivering Project ImPACT, an evidence-b…

    Stage

    Not phased

    Ages

    Any age

    Site

    Marcus Autism Center, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT07148258 on ClinicalTrials.gov