Autism Clinical Trials

53 studies are recruiting for autism in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Behavioral Activation for Treatment of Depression in Autistic Adolescents With Below Average Intelligence

   Autism spectrum disorder is characterized by differences in social communication/interaction and the presence of restricted/repetitive behaviors, with significant heterogeneity in terms of autistic features, language ability, and cognitive characteristics. About 2-3% of individuals in the United St…

   Stage

   Not phased

   Ages

   12 to 17

   Site

   Stony Brook University, Stony Brook, New York

   Run by

   Stony Brook University

   See if you can join NCT07812870 on ClinicalTrials.gov

2. Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation

   The goal of this study is to help children with autism and a co-occurring intellectual disability and their families learn practical strategies for managing issues like irritability, aggression, and other challenging behaviors. The main objective of this study is: To adapt current Regulating Togeth…

   Stage

   Not phased

   Ages

   8 to 12

   Site

   Children's Mercy, Kansas City, Missouri

   Run by

   Children's Mercy Hospital Kansas City

   See if you can join NCT07624448 on ClinicalTrials.gov

3. The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

   The purpose of this protocol is to allow for the careful evaluation of healthy volunteers and individuals with risk for psychiatric disorders or neurodevelopmental disorders, such as autism spectrum disorder for specific protocols at NIH.

   Stage

   Not phased

   Ages

   0 and older

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Mental Health (NIMH)

   See if you can join NCT00271622 on ClinicalTrials.gov

4. Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

   This 24-month study is testing whether adding AdiaVita, an umbilical cord blood-derived stem cell and exosome product, to glutathione therapy helps improve autism symptoms in children ages 3-12 more than glutathione alone. Children will be randomly placed into one of two groups for the first three …

   Stage

   Phase 1

   Ages

   3 to 12

   Site

   Adia Med Of Winter Park, Winter Park, Florida

   Locations

   2 in total

   Run by

   Adia Med of Winter Park LLC

   See if you can join NCT07304440 on ClinicalTrials.gov

5. Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum Disorder

   The goal of this clinical trial is to learn how prednisone affects adults with autism spectrum disorder (ASD). It will also learn about the safety of prednisone. The main questions it aims to answer are: * How does prednisone affect the core features and associated target symptoms of ASD in adults …

   Stage

   EARLY_Phase 1

   Ages

   18 to 50

   Site

   MGH Lurie Center for Autism, Lexington, Massachusetts

   Run by

   Christopher John McDougle, M.D.

   See if you can join NCT06934915 on ClinicalTrials.gov

6. The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

   The goal of this pilot intervention study is to examine the feasibility and acceptability of a novel bedtime manipulation protocol called "The Power Down" for autistic youth, ages 6-10. The main questions it aims to answer are: 1. Is the Power Down feasible for caregivers to do each night? 2. Do th…

   Stage

   Not phased

   Ages

   6 to 10

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06386029 on ClinicalTrials.gov

7. Differences in Rest, Emotion, and Arousal Modulation in Youth

   The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10). In a subset of children with elevated sensory responsivity, a sensory-based bedtime manipulation targe…

   Stage

   Not phased

   Ages

   6 to 10

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT07476937 on ClinicalTrials.gov

8. Improving Caregiver Engagement in Early Interventions

   The goal of this study is to test the effectiveness of the FANS-EI program in supporting caregiver engagement in caregiver-mediated early interventions for young children with autism. This study also examines caregiver-perceived social support and self-efficacy and FANS-EI implementation outcomes (…

   Stage

   Not phased

   Ages

   1 and older

   Site

   University of California, Davis MIND Institute, Sacramento, California

   Run by

   University of California, Davis

   See if you can join NCT07500363 on ClinicalTrials.gov

9. Family-Centered Implementation of Parent Training for Autistic Toddlers in Early Intervention

   Early Intervention (EI) systems are ill-equipped to serve the many children 12 to 36 months with early signs or a diagnosis of autism spectrum disorder (ASD). EI funded by Part C of the Individuals with Disabilities Education Act (IDEA) uses home-based service delivery, emphasizes family-centered c…

   Stage

   Not phased

   Ages

   1 to 3

   Site

   University of South Carolina, Columbia, South Carolina

   Run by

   University of South Carolina

   See if you can join NCT07471594 on ClinicalTrials.gov

10. A Toolkit to Improve Mental Health Treatment for Autistic Individuals

    This pilot study is funded by the Organization for Autism Research (OAR). We are conducting a pilot study to improve mental health treatment for autistic individuals. First, we will conduct remote focus groups to identify barriers to mental health treatment and methods to improve treatment. Based o…

    Stage

    Not phased

    Ages

    13 and older

    Site

    Florida International University, Miami, Florida

    Locations

    2 in total

    Run by

    Florida International University

    See if you can join NCT07539519 on ClinicalTrials.gov

11. A Study of Esomeprazole in Children With Autism

    Autism is a pervasive developmental disorder characterized by core deficits in social behavior and communication and the presence of repetitive/stereotyped behaviors. The objective of the study is to evaluate the efficacy of Esomeprazole as a treatment for social communication deficits in children …

    Stage

    Phase 2

    Ages

    2 to 6

    Site

    Stanford University School of Medicine, Stanford, California

    Run by

    Stanford University

    See if you can join NCT03866668 on ClinicalTrials.gov

12. Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth

    The purpose of this open label trial is to examine the preliminary feasibility, acceptability, and effectiveness of a 12-week behavioral intervention program (1 hour/week) to treat insistence on sameness (e.g., difficulty tolerating changes in routine) in youth with autism spectrum disorder (ASD). …

    Stage

    Not phased

    Ages

    4 to 17

    Site

    401 Quarry Road (Remote Study), Stanford, California

    Run by

    Stanford University

    See if you can join NCT06362733 on ClinicalTrials.gov

13. Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

    The aim of this clinical trial is to compare the efficacy of a 16-week center-based Pivotal Response Treatment (PRT-C) versus home-based Pivotal Response Treatment (PRT-H) in targeting social communication deficits in young children with autism spectrum disorder (ASD) with significant language dela…

    Stage

    Not phased

    Ages

    2 to 5

    Site

    Stanford University School of Medicine, Stanford, California

    Run by

    Stanford University

    See if you can join NCT04899544 on ClinicalTrials.gov

14. Early Diagnostic Response Model (EDRM)

    Babies Can't Wait (BCW) in Georgia will be referring families with children seeking an autism spectrum disorder (autism) diagnosis at the Emory Autism Center's (EAC) Child Screening and Assessment Clinic.The objective of this study is to develop, pilot, and evaluate a diagnostic protocol for childr…

    Stage

    Not phased

    Ages

    1 to 3

    Site

    Emory Autism Center, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT05419895 on ClinicalTrials.gov

15. Meeting the Needs of Young Hispanic Autistic Children

    Purpose of the Study: The goal of this clinical trial is to find out if a technique called the "mutual gaze procedure" used in a Culturally and Linguistically Responsive adaptation of Pathways Early Intervention (CLR-Pathways) is the key to improving social communication, language, and everyday ski…

    Stage

    Not phased

    Ages

    1 to 3

    Site

    Catholic Charities of Dallas, Dallas, Texas

    Locations

    3 in total

    Run by

    The University of Texas at Dallas

    See if you can join NCT06733584 on ClinicalTrials.gov

16. Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement

    The goal of this project is to measure the clinical utility of an objective and quantitative eye-tracking assay collected on a standalone, mobile investigational device to accurately screen 9-month-old infants for autism spectrum disorder and other actionable delays.

    Stage

    Not phased

    Ages

    0 to 0

    Site

    Children's Healthcare of Atlanta, Atlanta, Georgia

    Locations

    2 in total

    Run by

    Emory University

    See if you can join NCT05916430 on ClinicalTrials.gov

17. GAIP ASD Research Study

    This clinical research study evaluates the safety and preliminary effects of AdiaVita (umbilical cord blood-derived stem cells and exosomes) combined with glutathione versus glutathione alone in people aged 3 and older with Autism Spectrum Disorder (ASD). In this randomized, participant-blinded cro…

    Stage

    Phase 1

    Ages

    3 and older

    Site

    Greater Atlanta Integrative Pediatrics, Roswell, Georgia

    Locations

    2 in total

    Run by

    Greater Atlanta Integrative Pediatrics

    See if you can join NCT07622316 on ClinicalTrials.gov

18. Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

    The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers. Toddlers receive either Reciprocal Imitation Training (RIT), an evidence-based NDBI that supports children's imitation and s…

    Stage

    Not phased

    Ages

    1 to 3

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT05880225 on ClinicalTrials.gov

19. Online Pivotal Response Treatment Training in Autism Spectrum Disorder

    This is a research study that will assess the effects of a Pivotal Response Treatment Online Training Course (PRT-O) for training parents of children with Autism Spectrum Disorder (ASD). The study will specifically investigate whether participants can learn to deliver PRT effectively following part…

    Stage

    Not phased

    Ages

    2 to 5

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT06523387 on ClinicalTrials.gov

20. Evaluating Georgia Part C Implementation Outcomes

    This study aims to answer the question: What is the best way to help Early Intervention (EI) providers deliver high-quality services to children with communication delays for autism? The primary goal of this project is to examine the outcomes associated with delivering Project ImPACT, an evidence-b…

    Stage

    Not phased

    Ages

    Any age

    Site

    Marcus Autism Center, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT07148258 on ClinicalTrials.gov

21. Project Independence

    This project aims to develop and test the feasibility, acceptability, and preliminary impact of a brief, online single-session intervention (SSI) for caregivers of autistic youth ages 10 to 14. The SSI, called Project Independence, is designed to give caregivers practical tools to support greater i…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Miami, Coral Gables, Florida

    Run by

    University of Miami

    See if you can join NCT07572110 on ClinicalTrials.gov

22. Online Evaluation of the Diagnostic Accuracy of BlinkLab's Digital Assessments for Autism

    This observational study aims to evaluate how patterns of behavioral and sensorimotor responses measured using the BlinkLab Dx1 smartphone application relate to autism diagnoses in children ages 2 to 11. BlinkLab Dx1 is a non-invasive, smartphone-based application under development as a diagnostic …

    Stage

    Not phased

    Ages

    2 to 11

    Site

    Remote study conducted nationwide; all participation occurs via smartphone app at home., Princeton, New Jersey

    Run by

    Blinklab Limited

    See if you can join NCT07590973 on ClinicalTrials.gov

23. TF-CBT for Autistic Youth Pilot Implementation - Open Pilot

    Compared to the general population, autistic youth are at increased risk for both exposure to potentially traumatic events and trauma-related symptoms following trauma exposure. Autistic people identify approaches to effectively addressing trauma as a top mental health research priority, yet provid…

    Stage

    Not phased

    Ages

    6 and older

    Site

    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT07420478 on ClinicalTrials.gov

24. Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health

    The goal of this clinical trial is to test whether a smartphone-based data collection and feedback application ("Footsteps") improves the quality of behavioral data collected by one-to-one aides and leads to better youth mental health outcomes in school-aged youth (ages 4-17) who receive one-to-one…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT07042347 on ClinicalTrials.gov

25. The Feasibility of a Remote Problem-Solving Intervention for Autistic Adolescents or Young Adults and a Caregiver

    This project seeks to evaluate the feasibility and acceptability of a remote metacognitive strategy training intervention in transition-age autistic adolescents and young adults and a primary caregiver. We will also conduct limited efficacy testing.

    Stage

    Not phased

    Ages

    13 to 21

    Site

    University of Missouri - Columbia, Columbia, Missouri

    Run by

    University of Missouri-Columbia

    See if you can join NCT07216196 on ClinicalTrials.gov