Autism Spectrum Disorder Clinical Trials

104 studies are recruiting for autism spectrum disorder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 4

1. Optimizing Outcomes for Young Autistic Children

   The overarching goal of the proposed study is to: (a) determine how best to sequence two parent-mediated interventions: a social communication intervention (Project ImPACT, Improving Parents as Communication Teachers) and a disruptive behavior intervention (Parent Training for Disruptive Behavior) …

   Stage

   Phase 2

   Ages

   1 to 4

   Site

   Northwestern University, Evanston, Illinois

   Run by

   Northwestern University

   See if you can join NCT05926687 on ClinicalTrials.gov

2. Harnessing Communication Preferences

   The goal of this clinical trial is to evaluate how preference for communication approach (e.g., using a touch talker versus picture cards) impacts treatment maintenance in the context of treatment to reduce challenging behavior exhibited by individuals with intellectual and/or developmental disabil…

   Stage

   Not phased

   Ages

   2 to 90

   Site

   University of Georgia, Athens, Georgia

   Locations

   2 in total

   Run by

   Joel E. Ringdahl

   See if you can join NCT07278544 on ClinicalTrials.gov

3. Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism

   Autism spectrum disorder (ASD) is a very heterogeneous disorder with limited empirically validated behavioral and biological interventions. The goal of this pilot investigation is to apply a biologically-based approach to identify predictors of treatment response in children with ASD who are receiv…

   Stage

   Not phased

   Ages

   2 to 4

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT03583684 on ClinicalTrials.gov

4. Cannabidiol (CBD) in Adults With ASD

   There are no FDA approved treatments for use in adults with autism spectrum disorder (ASD), many of whom have distressing anxiety, mood disturbances, sleep problems, and agitation. Some researchers and individuals with ASD have noted that cannabidiol (CBD) is beneficial for those psychiatric proble…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   JHBMC, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT05015439 on ClinicalTrials.gov

5. Social Groups for Autistic Young Adults (SDARIYA)

   This is a clinical trial that will test whether a group program called SDARI (Socio-dramatic Affective Relational Intervention) can help autistic young adults between the ages of 18 and 30 feel more connected to others and improve their social relationships. The study will try to answer: Can SDARI …

   Stage

   Not phased

   Ages

   18 to 30

   Site

   Drexel University, Philadelphia, Pennsylvania

   Run by

   Drexel University

   See if you can join NCT07222982 on ClinicalTrials.gov

6. AWARE: Management of ADHD in Autism Spectrum Disorder

   This study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents with autism. Using a sequential, multiple assignment randomization trial (SMART) design the study will…

   Stage

   Phase 4

   Ages

   4 to 17

   Site

   University of California, Irvine, Irvine, California

   Locations

   12 in total

   Run by

   Daniel Coury

   See if you can join NCT05916339 on ClinicalTrials.gov

7. Resources for Optimizing Outcomes in Toddlers on the Spectrum

   The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for toddlers under the age of 4 living in Rural NC after their initial diagnosis of autism. The main questions it aim…

   Stage

   Not phased

   Ages

   1 to 99

   Site

   Carolina Institute for Developmental Disabilities, Carrboro, North Carolina

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT07086781 on ClinicalTrials.gov

8. Longitudinal Study of Neurogenetic Disorders

   The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment. The investigators will maintain an ongoing database of medical data that is otherwise being collected for ro…

   Stage

   Not phased

   Ages

   Any age

   Site

   Columbia University Irving Medical Center, New York, New York

   Run by

   Columbia University

   See if you can join NCT03492060 on ClinicalTrials.gov

9. Word Learning From Parentese in Autistic Children

   The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are factors that influence the effect of parentese on word learning (Aim 3).

   Stage

   Not phased

   Ages

   1 to 4

   Site

   University of Texas at Dallas, Richardson, Texas

   Run by

   The University of Texas at Dallas

   See if you can join NCT06649916 on ClinicalTrials.gov

10. Cannabidivarin (CBDV) vs. Placebo in Children With Autism Spectrum Disorder (ASD)

    This trial aims to study the efficacy and safety of cannabidivarin (CBDV) in children with ASD.

    Stage

    Phase 2

    Ages

    5 to 18

    Site

    Montefiore Medical Center, The Bronx, New York

    Locations

    2 in total

    Run by

    Montefiore Medical Center

    See if you can join NCT03202303 on ClinicalTrials.gov

11. Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder

    This study will consist of a randomized, double-blind, sham-controlled clinical trial at SUNY Upstate Medical University and Mt. Sinai Medical Center with 80 autistic children evaluating the effects of transcranial photobiomodulation (tPBM) on multiple clinically validated scales.

    Stage

    Not phased

    Ages

    2 to 8

    Site

    Mt. Sinai Medical Center, New York, New York

    Locations

    2 in total

    Run by

    State University of New York - Upstate Medical University

    See if you can join NCT06006637 on ClinicalTrials.gov

12. Cerebellum and Autism: Regional Specialization for Social and Executive Functions

    The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.

    Stage

    Not phased

    Ages

    18 to 35

    Site

    American University, Washington D.C., District of Columbia

    Run by

    American University

    See if you can join NCT05396352 on ClinicalTrials.gov

13. Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

    Autistic adults are at a greater risk for mental health problems compared to the general population, with 50% meeting criteria for a co-occurring psychiatric condition. Depression and anxiety are the most common of these conditions among autistic adults, contributing to long-term detrimental effect…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

    Locations

    2 in total

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT06060860 on ClinicalTrials.gov

14. Cerebellar Transcranial Direct Current Stimulation (tDCS) in Children With Autism Spectrum Disorder: Raynor Cerebellum Project

    The purpose of this research study is to investigate the effects of transcranial direct current stimulation (tDCS) on some of the challenges faced by children with Autism Spectrum Disorder (ASD).

    Stage

    Not phased

    Ages

    5 to 21

    Site

    UT Southwestern Medical Center, Dalls, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT05691283 on ClinicalTrials.gov

15. Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

    Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.

    Stage

    Not phased

    Ages

    12 to 45

    Site

    Stanford University, Stanford, California

    Run by

    Stanford University

    See if you can join NCT04532424 on ClinicalTrials.gov

16. School-based Paraeducator Education for Engagement at Recess

    The purpose of the proposed three-site study is to test whether an educator-level implementation strategy, coaching, with or without a school-level implementation strategy, school-based teams, will maximize paraeducators' use (fidelity and sustainment) of an evidence-based social engagement interve…

    Stage

    Not phased

    Ages

    5 and older

    Site

    University of Washington, Seattle, Washington

    Locations

    3 in total

    Run by

    University of Washington

    See if you can join NCT06559267 on ClinicalTrials.gov

17. Application of Virtual Reality Technology to Treatment of Social Anxiety

    The purpose of this study is to compare CBT VR exposure + VR social skills treatment to CBT Imaginal exposure + mindfulness, in reducing the severity of social anxiety in adults with autism and social anxiety (SA), to identify characteristics associated with benefitting from the CBT-VR treatment an…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Texas Health Science Center at Houston, Houston, Texas

    Run by

    The University of Texas Health Science Center, Houston

    See if you can join NCT06845488 on ClinicalTrials.gov

18. Brain Activity Changes After Cognitive Behavioral Therapy for Anxiety in Autistic Youth From High-Need Communities

    The goal of this clinical trial is to investigate neural constructs related to anxiety symptoms in response to Facing Your Fears (FYF) treatment in autistic participants with co-occurring anxiety. Researchers will compare participants receiving immediate FYF intervention to those in the waitlist co…

    Stage

    Not phased

    Ages

    8 to 14

    Site

    Montclair State University, Montclair, New Jersey

    Locations

    2 in total

    Run by

    Montclair State University

    See if you can join NCT06904508 on ClinicalTrials.gov

19. ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

    ADNP, also known as Activity Dependent Neuroprotective Protein, is a rare neurodevelopmental disorder caused by mutations encompassing the ADNP gene on chromosome 20. Clinically, ADNP syndrome is characterized by intellectual disability and global developmental delay. This study seeks to characteri…

    Stage

    Not phased

    Ages

    2 and older

    Site

    The Seaver Autism Center for Research and Treatment, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT03718936 on ClinicalTrials.gov

20. A Comparison of Two School Based Interventions to Manage Anxiety in Autistic Students

    The goal of this clinical trial is to compare two school based interventions to manage anxiety in autistic students. The main question[s] it aims to answer are: 1) Compare the effectiveness of Facing Your Fears-School Based Program (FYF-SB) with Zones of Regulation (ZOR) on anxiety reduction and em…

    Stage

    Not phased

    Ages

    7 to 15

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT05863520 on ClinicalTrials.gov

21. More and Less Social Comprehension

    The goal of this early Phase 1 clinical trial is to assess if the social content of a story impacts autistic children's listening comprehension of stories. The main questions this study aims to answer are: * Does removing social content from a story improve listening comprehension in autistic child…

    Stage

    Not phased

    Ages

    9 to 12

    Site

    University of Kansas Comprehension and Language Learning Lab, Lawrence, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT06116552 on ClinicalTrials.gov

22. Autism Doula Program Evaluation

    Background: Findings from a group level assessment with caregivers of Black children with autism revealed barriers to equitable care and services (e.g., a lack of cultural representation among their child's care team, caregiver stress, stigma, and uncertainty about services needed). The Autism Doul…

    Stage

    Not phased

    Ages

    1 to 5

    Site

    Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT06896942 on ClinicalTrials.gov

23. Abnormal Connectivity Involving the Social Reciprocity Network in Autism and the Impact of Neurostimulation in Mitigating the Abnormalities

    There is no consensus regarding the neurological substrate underpinning ASD. The investigators describe the novel concept of "social reciprocity network" and hypothesize that aberrant connectivity/oscillatory patterns affecting this network contribute to the core deficits in ASD. The overarching go…

    Stage

    Not phased

    Ages

    13 to 18

    Site

    Christiana Care, Newark, Delaware

    Run by

    Christiana Care Health Services

    See if you can join NCT06807684 on ClinicalTrials.gov

24. Pilot Trial of the RUBI Program for Autistic Adults

    The goal of this clinical trial is to evaluate if a redesigned version of the RUBI parenting intervention can reduce challenging behaviors and improve adaptive skills in autistic adults with co-occurring challenging behaviors. The main questions it aims to answer are: * Is the redesigned RUBI inter…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Seattle Children's Autism Center, Seattle, Washington

    Locations

    3 in total

    Run by

    Seattle Children's Hospital

    See if you can join NCT06593613 on ClinicalTrials.gov

25. Peer Interventions for Preschoolers With Autism

    This proposal will evaluate a series of peer-mediated interventions (PMIs) for preschool children (3 to 6 years) with ASD and limited or no spoken language, using an innovative Sequential Multiple Assignment Randomized Trial (SMART) design. Available evidence supports the beneficial effects of PMIs…

    Stage

    Not phased

    Ages

    3 to 6

    Site

    Juniper Gardens Children's Project, Kansas City, Kansas

    Locations

    2 in total

    Run by

    University of Kansas

    See if you can join NCT05799599 on ClinicalTrials.gov