Atrial Fibrillation Clinical Trials

64 studies are recruiting for atrial fibrillation in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation

   The goal of the study is to learn how a weight loss medication called semaglutide, which is used to treat obesity, in addition to standard AF treatment might affect AF, atrial fibrillation severity, and whether it changes the risk of atrial fibrillation recurring after standard AF treatments.

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   University of Chicago, Chicago, Illinois

   Locations

   2 in total

   Run by

   University of Chicago

   See if you can join NCT06499857 on ClinicalTrials.gov

2. Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

   The purpose of this prospective, randomized, double-blinded study is to further evaluate the safety and efficacy of varying doses of intravenous magnesium in the treatment of AFF RVR.

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Advocate Christ Medical Center Emergency Department (ACMC ED), Oak Lawn, Illinois

   Run by

   Wake Forest University Health Sciences

   See if you can join NCT06376916 on ClinicalTrials.gov

3. Intracardiac Echocardiography Guided Watchman Device Implant

   This study is to look at the success of Intracardiac Echocardiography (ICE) in the Watchman procedure. Currently the process is to use a Transesophageal Echocardiography (TEE) to place the Watchman in patients. This study is aiming to show how the ICE is just as effective in placing the device corr…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT06007872 on ClinicalTrials.gov

4. Implanted Loop Recorders for Detection and Management of Arrhythmia With Bruton Tyrosine Kinase Inhibitors

   This study will enroll patients initiating Bruton Tyrosine Kinase (BTK) inhibitors without history of documented arrhythmia while on therapy using the Medtronic LINQ-2 insertable cardiac monitor (ILR). The incidence of new onset atrial fibrillation (AF) and other arrhythmia will be determined. Acti…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Northwell (Northshore University/Long Island Jewish Hospitals), New Hyde Park, New York

   Run by

   Northwell Health

   See if you can join NCT05643235 on ClinicalTrials.gov

5. Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure

   This is a prospective, single center, non-randomized study with two parallel arms intended to study if 4D Intracardiac echocardiography (4D-ICE) (Nuvision, Nuvera TM) will provide better visualization of the anatomical landmarks from the larger imaging volume and provide optimal intra procedural gu…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Kansas City Heart Rhythm Institute - Roe Clinic, Overland Park, Kansas

   Run by

   Kansas City Heart Rhythm Research Foundation

   See if you can join NCT06061757 on ClinicalTrials.gov

6. Long-Term Outcomes of LAA Contrast Flow in CT Scans After Endocardial LAA Closure: The CF-CT Registry

   This study is intended to assess the incidence and correlation to the development of peri-device leaks (PDLs), device related thrombosis (DRTs) and cerebral vascular accident (CVA)/transient ischemic attacks (TIAs) in association with left atrial appendage contrast flow (LAA-CF). It will be a multi…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Kansas City Heart Rhythm Institute, Overland Park, Kansas

   Run by

   Kansas City Heart Rhythm Research Foundation

   See if you can join NCT06075628 on ClinicalTrials.gov

7. Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

   In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger…

   Stage

   Phase 4

   Ages

   18 to 100

   Site

   University of Illinois at Chicago, Chicago, Illinois

   Locations

   4 in total

   Run by

   University of Illinois at Chicago

   See if you can join NCT02347111 on ClinicalTrials.gov

8. Pericardiotomy in Cardiac Surgery

   PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Weill Cornell Medicine, New York, New York

   Locations

   4 in total

   Run by

   Population Health Research Institute

   See if you can join NCT06486636 on ClinicalTrials.gov

9. Get With the Guidelines Atrial Fibrillation Registry

   Get With The Guidelines-Atrial Fibrillation is designed to assist hospital care teams in consistently providing the latest evidence-based treatment for their AFib patients. At the same time, it offers a means of monitoring the quality of AFib care in U.S. hospitals and building a database for conti…

   Stage

   Not phased

   Ages

   18 to 125

   Site

   Amy Bennett, Dallas, Texas

   Run by

   American Heart Association

   See if you can join NCT06245187 on ClinicalTrials.gov

10. Vascular Closure With a Device Compared to Manual Compression After Atrial Fibrillation Ablation: The LockeT II Study

    The LockeT II study is a single center, prospective randomized study. It is intended to study the effectiveness of using LockeT device to gain hemostasis after venous procedures as compared to Manual Compression (MC). Approximately 110 patients will be enrolled.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Kansas City Heart Rhythm Institute - Roe Clinic, Overland Park, Kansas

    Locations

    6 in total

    Run by

    Kansas City Heart Rhythm Research Foundation

    See if you can join NCT06078735 on ClinicalTrials.gov

11. Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

    This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure. Patients undergoing heart surgery at Brigham and Women's Hospital and Texas Heart Institute are eligible to participate.

    Stage

    Not phased

    Ages

    20 to 90

    Site

    UT Southwestern Medical Center, Dallas, Texas

    Locations

    3 in total

    Run by

    Brigham and Women's Hospital

    See if you can join NCT01258231 on ClinicalTrials.gov

12. CardioFocus HeartLight Post-Approval Study

    This is a post-approval study to evaluate the clinical outcomes in a cohort of participants treated during commercial use of the HeartLight System to confirm results of the previously conducted pivotal clinical study.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Arizona Sarver HeartCenter, Tucson, Arizona

    Locations

    4 in total

    Run by

    CardioFocus

    See if you can join NCT03168659 on ClinicalTrials.gov

13. MANAGE-AF Registry -MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)

    The purpose of this research is to learn more about the normal care of patients with a new or pre-existing diagnosis of atrial fibrillation (AF). These abnormal and irregular heartbeats place patients at increased risk of developing clots in their bloodstream that could potentially lead to stroke. …

    Stage

    Not phased

    Ages

    18 and older

    Site

    CorVita Science Foundation (NFP), Chicago, Illinois

    Run by

    CorVita Science Foundation

    See if you can join NCT05978466 on ClinicalTrials.gov

14. Chloroquine for Patients With Symptomatic Persistent Atrial Fibrillation: A Prospective Pilot Study

    The goal of this pilot study is to explore the efficacy of chloroquine in terminating persistent AF and assess its potential role as a pharmacological cardioversion agent for the management of AF.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of South Florida, Tampa, Florida

    Run by

    University of South Florida

    See if you can join NCT02932007 on ClinicalTrials.gov