Asthma Clinical Trials

63 studies are recruiting for asthma in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Asthma Symptom Perception Study

   Asthma affects 8% of the United States population ages >60 years and causes considerable harm: older adults are 4 times more likely to die from asthma and have twice the risk of hospitalization. The burden of asthma is notably greater among minoritized older adults. Research suggests that perceptio…

   Stage

   Not phased

   Ages

   60 and older

   Site

   Ichan School of Medicine at Mount Sinai, New York, New York

   Locations

   2 in total

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT06612294 on ClinicalTrials.gov

2. SMART@Home Feasibility Trial

   The proposed research addresses the limitations or lack of a digital platform to provide remote care of medically complex patients. Previous attempts have had poor clinical validity and suffered lack of patient engagement. The study team will deconstruct the previously implemented SMART platforms t…

   Stage

   Not phased

   Ages

   12 to 18

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT06159127 on ClinicalTrials.gov

3. Depemokimab Asthma Imaging and Bronchoscopy Sub-Study

   Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and worsen unpredictably.\xa0The purpose of this study is to assess how depemokimab, a monoclonal antibody, affects the structure and function of the lungs in asthmat…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   GSK Investigational Site, Brooksville, Florida

   Locations

   50 in total

   Run by

   GlaxoSmithKline

   See if you can join NCT06979323 on ClinicalTrials.gov

4. Protocol CAUSE-03 / CHEETAH

   This is a one-year longitudinal, observational study of 250 urban children and adolescents with asthma and 60 without asthma, ages 6-17 years old. Participants with asthma will require daily controller therapy with inhaled corticosteroids ICS (at least Step 2 therapy). Those without asthma cannot h…

   Stage

   Not phased

   Ages

   6 to 17

   Site

   Children's Hospital Colorado: Allergy Program, Aurora, Colorado

   Locations

   8 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT06136091 on ClinicalTrials.gov

5. Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects

   This study incorporates objectives directed at two subject cohorts: 1. Uncontrolled Adult and Pediatric Asthma Subjects: To demonstrate a statistically significant and clinically meaningful decline in Point Of Care (POC) FeNO as measured by the fenoTRACK device, after an approximately 2-week course…

   Stage

   Not phased

   Ages

   5 to 100

   Site

   Bensch Clinical Research LLC, Stockton, California

   Locations

   13 in total

   Run by

   Biometry Inc

   See if you can join NCT07228026 on ClinicalTrials.gov

6. Microglia Activation in Asthma

   The goal of this clinical trail is to learn about how asthma influences brain function. The main questions it aims to answer are: * How airway inflammation in asthma affects the brain; and, * Whether airway inflammation in asthma is related to symptoms of depression and anxiety Over the course of 6…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   University of Wisconsin Madison, Madison, Wisconsin

   Run by

   University of Wisconsin, Madison

   See if you can join NCT04307667 on ClinicalTrials.gov

7. Asthma and Technology in Emerging African American Adults

   The purpose of the ATHENA Project is to test a mobile health intervention to help African American young adults better manage their asthma. The program has four components: 1) a web-based, mobile asthma program delivered to participants' mobile device, 2) meetings with an asthma nurse via video con…

   Stage

   Not phased

   Ages

   18 to 30

   Site

   University of Michigan, Ann Arbor, Michigan

   Locations

   3 in total

   Run by

   University of Michigan

   See if you can join NCT05445583 on ClinicalTrials.gov

8. Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

   The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.

   Stage

   Phase 1

   Ages

   3 and older

   Site

   University of Kansas Medical Center, Kansas City, Kansas

   Run by

   Mario Castro, MD, MPH

   See if you can join NCT04624490 on ClinicalTrials.gov

9. Ventilation and Perfusion in Asthmatics

   Assess regional changes to perfusion and ventilation from inhaled corticosteroid (ICS) and Fast-acting beta-antagonist (FABA) among adult asthmatics using radiographically derived estimates of regional ventilation (V-distribution), ventilation defect percentage (VDP), and ventilation heterogeneity …

   Stage

   Phase 4

   Ages

   18 to 75

   Site

   University of Miami - Converge Miami, Miami, Florida

   Run by

   University of Miami

   See if you can join NCT07426458 on ClinicalTrials.gov

10. A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

    The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning o…

    Stage

    Phase 2

    Ages

    18 to 70

    Site

    Velocity Clinical Research, Mobile, Mobile, Alabama

    Locations

    132 in total

    Run by

    Pfizer

    See if you can join NCT06977581 on ClinicalTrials.gov

11. Mechanistic Insights From Bronchoscopy Airway Samples

    The purpose of this study is to examine the mechanisms of asthma. The investigators are comparing the cells of individuals with and without asthma and looking at the roles various parts of the cell play in the production and secretion of mucus.

    Stage

    Not phased

    Ages

    18 to 70

    Site

    University of California, San Francisco, San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT06105710 on ClinicalTrials.gov

12. 45th Multicenter Airway Research Collaboration

    The study is a randomized controlled trial on the effect of emergency department initiation of Airsupra on acute asthma "recurrence" at 3 months and other related outcomes (acute asthma relapse, asthma control).

    Stage

    Phase 4

    Ages

    18 to 54

    Site

    MetroHealth, Cleveland, Ohio

    Run by

    Massachusetts General Hospital

    See if you can join NCT07166939 on ClinicalTrials.gov

13. Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being

    The goal of this pilot clinical trial is to learn if a community referral program can improve services for youth with mental health and chronic health conditions in a predominantly Native Hawaiian and Pacific Islander community. The main questions the trial aims to address are: * What is the best w…

    Stage

    Not phased

    Ages

    12 to 25

    Site

    Waianae Coast Comprehensive Health Center, Waianae, Hawaii

    Run by

    Waianae Coast Comprehensive Health Center

    See if you can join NCT07536256 on ClinicalTrials.gov

14. VENTURI (VENTilation Using Respiratory Imaging)

    The purpose of the study is to enroll participants with uncontrolled asthma to evaluate the large and small airways and drug delivery utilizing two study drugs: * Beclometasone dipropionate/Formoterol fumarate dihydrate/Glycopyrronium bromide (BDP/FF/G) or Trimbow * Fluticasone furoate/Umeclidinium…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    The University of Alabama at Birmingham, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT07282886 on ClinicalTrials.gov

15. Home Hospital for Suddenly Ill Adults

    The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be delivered in the home with equal quality and safety, reduced cost, and impro…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Locations

    2 in total

    Run by

    Brigham and Women's Hospital

    See if you can join NCT03524222 on ClinicalTrials.gov

16. Hospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care

    Caregiver-child dyads will be recruited during child's hospital admission for asthma exacerbation. Recruitment sites will be mainly Children's National Hospital Sheikh Zayed campus, as well as regional partners: Holy Cross Hospital, and Mary Washington Hospital. After enrollment, baseline data will…

    Stage

    Not phased

    Ages

    4 to 12

    Site

    Children's National Hospital, Washington D.C., District of Columbia

    Run by

    Kavita Parikh

    See if you can join NCT05991115 on ClinicalTrials.gov

17. The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)

    Investigators are studying how a device called The Lung Master device can help people breathe better. The investigational device increases the amount of air our lungs can hold, which is important for overall lung health. The Lung Master is not approved by the FDA. The study has two visits approxima…

    Stage

    Not phased

    Ages

    19 and older

    Site

    Biomechanics Research Building, Omaha, Nebraska

    Run by

    University of Nebraska

    See if you can join NCT06524856 on ClinicalTrials.gov

18. BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma

    This study is an efficacy-implementation trial to: 1. evaluate systematically the efficacy of BREATHE in 200 Black adults receiving care at urban federally qualified health centers (FQHCs) for uncontrolled asthma; and 2. identify multi-level barriers and facilitators to the widespread adoption and …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Sun River Health, Beacon, New York

    Locations

    2 in total

    Run by

    Columbia University

    See if you can join NCT05341726 on ClinicalTrials.gov

19. Escitalopram in Asthma Patients With Frequent Exacerbation

    Antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), such as escitalopram are widely used for mood and anxiety disorders. However, they have also been explored, with promising findings, for a variety of disorders outside of psychiatry. Clinical studies of SSRIs in depresse…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    UT Southwestern, 1440 Empire Central, Ste. LD4.100, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT06216535 on ClinicalTrials.gov

20. Reducing Overuse of Antibiotics With Decision Support

    Eliminating inappropriate antibiotic use in pediatric lower respiratory tract infections (LRTI) is the central focus of this research. LRTIs (pneumonia, bronchiolitis, and infection-related exacerbations of asthma) account for nearly one-third of all emergency department (ED) visits and 40% of all …

    Stage

    Not phased

    Ages

    0 to 17

    Site

    Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, Tennessee

    Locations

    3 in total

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT06788093 on ClinicalTrials.gov

21. Metformin IN Asthma for Overweight and Obese Individuals (MINA)

    This is a randomized clinical trial of metformin among overweight or obese adults with not well-controlled asthma despite maintenance inhaler therapy.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Johns Hopkins University, Baltimore, Maryland

    Locations

    2 in total

    Run by

    Johns Hopkins University

    See if you can join NCT06273072 on ClinicalTrials.gov

22. Individualizing Treatment for Asthma in Primary Care (Full Study)

    While asthma therapy is becoming more individualized based on asthma phenotypes, more research is needed to tailor newer therapies to individuals. Inhaled corticosteroid (ICS) medications are the foundation of care for all individuals with persistent asthma. But ICS use is not without possible long…

    Stage

    Phase 4

    Ages

    13 to 75

    Site

    DARTNet Institute, Aurora, Colorado

    Locations

    13 in total

    Run by

    DARTNet Institute

    See if you can join NCT07052942 on ClinicalTrials.gov

23. Acoustic Waveform Respiratory Evaluation

    The study will evaluate the feasibility of using smartphone speakers and microphones to evaluate the caliber of the airways, detect airway obstruction, aid in airway disease diagnosis, and identify disease exacerbations.

    Stage

    Not phased

    Ages

    8 to 70

    Site

    Indiana University, Indianapolis, Indiana

    Locations

    2 in total

    Run by

    Indiana University

    See if you can join NCT06512064 on ClinicalTrials.gov

24. AeviceMD for Detection of Wheeze in Pediatric and Adult Populations

    Respiratory signs and symptoms consisting of wheeze, cough, and breathlessness are obtained in a manual fashion through history taking and physical examination by the healthcare professional. Auscultation of the lung assesses airflow through the trachea-bronchial tree and is helpful in diagnosing v…

    Stage

    Not phased

    Ages

    3 and older

    Site

    Montefiore Medical Center, The Bronx, New York

    Run by

    Aevice Health Pte. Ltd.

    See if you can join NCT06691971 on ClinicalTrials.gov

25. Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

    Asthma is a heterogeneous disorder in which multiple potential inflammatory pathways contribute to airway obstruction. The biological basis for airway inflammation is the subject of intensive investigation. This work is designed to identify airway factors that are responsible for recruiting cells a…

    Stage

    Phase 1

    Ages

    18 to 50

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Benjamin Medoff

    See if you can join NCT00595491 on ClinicalTrials.gov