Asthma Clinical Trials

68 studies are recruiting for asthma in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

   This is a dose-range finding, double-blind, placebo-controlled, phase IIb study designed to assess efficacy and safety of tozorakimab administered subcutaneously in adult participants with uncontrolled asthma receiving medium-to-high dose inhaled corticosteroids.

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   Research Site, Bakersfield, California

   Locations

   223 in total

   Run by

   AstraZeneca

   See if you can join NCT06932263 on ClinicalTrials.gov

2. A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma

   The purpose of this clinical study is to learn about the safety and effects of the study medicine (called tilrekimig) for the potential treatment of severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life of people who are affected. Th…

   Stage

   Phase 3

   Ages

   12 to 80

   Site

   Kern Research, Inc., Bakersfield, California

   Locations

   16 in total

   Run by

   Pfizer

   See if you can join NCT07772921 on ClinicalTrials.gov

3. NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)

   Background: - Asthma is a serious clinical and public health problem. Researchers want to collect data to better understand how bacteria and other things in the environment can affect people's asthma. Eligibility: - Nonsmoking adults age 18 - 60 who have moderate to severe asthma. Design: * Partici…

   Stage

   Not phased

   Ages

   18 to 60

   Site

   NIEHS Clinical Research Unit (CRU), Research Triangle Park, North Carolina

   Run by

   National Institute of Environmental Health Sciences (NIEHS)

   See if you can join NCT02327897 on ClinicalTrials.gov

4. Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment

   The rationale of the roll-over study (ROSY) is to provide continuous access to study treatment for participants who have completed or exited a parent study and are deemed appropriate for continued benralizumab treatment, as judged by the Investigator, while monitoring long-term safety and tolerabil…

   Stage

   Phase 3

   Ages

   6 and older

   Site

   Research Site, Buenos Aires,

   Locations

   47 in total

   Run by

   AstraZeneca

   See if you can join NCT07444567 on ClinicalTrials.gov

5. Role of Genetic Factors in the Development of Lung Disease

   This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible fo…

   Stage

   Not phased

   Ages

   2 to 90

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Locations

   2 in total

   Run by

   National Heart, Lung, and Blood Institute (NHLBI)

   See if you can join NCT00001532 on ClinicalTrials.gov

6. Study of the Effect of Innate on the Inflammatory Response to Endotoxin

   Background: - Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation. Researchers are interested in studying how the body responds to certain environmental factors, and whether the body s re…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   NIEHS Clinical Research Unit (CRU), Research Triangle Park, North Carolina

   Run by

   National Institute of Environmental Health Sciences (NIEHS)

   See if you can join NCT01143480 on ClinicalTrials.gov

7. BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma

   This study is an efficacy-implementation trial to: 1. evaluate systematically the efficacy of BREATHE in 200 Black adults receiving care at urban federally qualified health centers (FQHCs) for uncontrolled asthma; and 2. identify multi-level barriers and facilitators to the widespread adoption and …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Sun River Health, Beacon, New York

   Locations

   2 in total

   Run by

   Columbia University

   See if you can join NCT05341726 on ClinicalTrials.gov

8. Ventilation and Perfusion in Asthmatics

   Assess regional changes to perfusion and ventilation from inhaled corticosteroid (ICS) and Fast-acting beta-antagonist (FABA) among adult asthmatics using radiographically derived estimates of regional ventilation (V-distribution), ventilation defect percentage (VDP), and ventilation heterogeneity …

   Stage

   Phase 4

   Ages

   18 to 75

   Site

   University of Miami - Converge Miami, Miami, Florida

   Run by

   University of Miami

   See if you can join NCT07426458 on ClinicalTrials.gov

9. A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

   The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma. Study participation will last approximately 65 weeks, including screening, treatment, and follow-up periods.

   Stage

   Phase 2

   Ages

   18 to 75

   Site

   AMR Clinical, Tempe, Arizona

   Locations

   119 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07219173 on ClinicalTrials.gov

10. Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma

    This is a global Phase 2 study divided in two parts. Part A is a double-blind, randomized dose-range finding study in adults with moderate to severe asthma to confirm the dosing regimen of WIN378 that can be tested in future pivotal trials for efficacy and safety. Part B is a pivotal double-blind, …

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    WB Contracted Clinical Research Site, Melbourne, Florida

    Locations

    73 in total

    Run by

    Windward Bio

    See if you can join NCT07120503 on ClinicalTrials.gov

11. The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)

    Investigators are studying how a device called The Lung Master device can help people breathe better. The investigational device increases the amount of air our lungs can hold, which is important for overall lung health. The Lung Master is not approved by the FDA. The study has two visits approxima…

    Stage

    Not phased

    Ages

    19 and older

    Site

    Biomechanics Research Building, Omaha, Nebraska

    Run by

    University of Nebraska

    See if you can join NCT06524856 on ClinicalTrials.gov

12. Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Pulmonary Diseases

    This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Pulmonary Diseases

    Stage

    Phase 1

    Ages

    Any age

    Site

    Prodromos Stem Cell Institute, Naples, Florida

    Locations

    2 in total

    Run by

    The Foundation for Orthopaedics and Regenerative Medicine

    See if you can join NCT05147688 on ClinicalTrials.gov

13. Metformin IN Asthma for Overweight and Obese Individuals (MINA)

    This is a randomized clinical trial of metformin among overweight or obese adults with not well-controlled asthma despite maintenance inhaler therapy.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Johns Hopkins University, Baltimore, Maryland

    Locations

    2 in total

    Run by

    Johns Hopkins University

    See if you can join NCT06273072 on ClinicalTrials.gov

14. A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

    To assess the efficacy and safety of tezepelumab in pediatric participants with severe uncontrolled asthma on medium to high-dose inhaled corticosteroids (ICS) and at least one additional asthma controller medication with or without oral corticosteroids.

    Stage

    Phase 3

    Ages

    5 to 11

    Site

    Research Site, Montgomery, Alabama

    Locations

    147 in total

    Run by

    AstraZeneca

    See if you can join NCT06023589 on ClinicalTrials.gov

15. Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

    The purpose of this study is to compare the effect of budesonide/albuterol metered-dose inhaler (BDA MDI) with albuterol sulfate metered-dose inhaler (AS MDI), both administered as needed, on the annualized rate of severe asthma exacerbations in adolescents with a documented clinical diagnosis of a…

    Stage

    Phase 3

    Ages

    12 to 17

    Site

    Research Site, Anchorage, Alaska

    Locations

    155 in total

    Run by

    AstraZeneca

    See if you can join NCT06307665 on ClinicalTrials.gov

16. A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

    The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning o…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    Velocity Clinical Research, Mobile, Mobile, Alabama

    Locations

    137 in total

    Run by

    Pfizer

    See if you can join NCT06977581 on ClinicalTrials.gov

17. A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma

    The purpose of this study is to evaluate the effect of 2 different GP metered dose inhaler (MDI) doses relative to placebo MDI as add-on treatment to BFF MDI on lung function in participants 4 to less than 12 years of age with asthma.

    Stage

    Phase 2

    Ages

    4 to 11

    Site

    Research Site, Bakersfield, California

    Locations

    44 in total

    Run by

    AstraZeneca

    See if you can join NCT07525375 on ClinicalTrials.gov

18. A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma

    The purpose of this study is to learn about the safety of a new study medicine called PF-08103402 in healthy adults (do not have disease) and or in adults with mild-to-moderate asthma. This is the first time the study medicine is being given to people. For Parts A, B, C, D and F, the study is seeki…

    Stage

    Phase 1

    Ages

    18 to 65

    Site

    Pfizer Clinical Research Unit - New Haven, New Haven, Connecticut

    Run by

    Pfizer

    See if you can join NCT07660731 on ClinicalTrials.gov

19. A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

    The main aim of the study to describe the characteristics of participants with asthma across the spectrum of disease severity, including sociodemographic and clinical characteristics, treatment and disease burden, biomarkers, and both disease-specific and generic health-related quality of life. The…

    Stage

    Not phased

    Ages

    6 and older

    Site

    Trinity Clinical Research, LLC - Bessemer - Site Number: 840150, Bessemer, Alabama

    Locations

    71 in total

    Run by

    Sanofi

    See if you can join NCT07556159 on ClinicalTrials.gov

20. A Study to Learn About the Study Medicine Called Tilrekimig ( PF-07275315) in People With Severe Asthma

    The purpose of this clinical study is to learn about the safety and effects of the study medicine (called tilrekimig) for the potential treatment of severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life of people who are affected. Th…

    Stage

    Phase 3

    Ages

    12 to 80

    Site

    Allergy and Clinical Immunology Associates, Pittsburgh, Pennsylvania

    Locations

    3 in total

    Run by

    Pfizer

    See if you can join NCT07869043 on ClinicalTrials.gov

21. SMART@Home Feasibility Trial

    The proposed research addresses the limitations or lack of a digital platform to provide remote care of medically complex patients. Previous attempts have had poor clinical validity and suffered lack of patient engagement. The study team will deconstruct the previously implemented SMART platforms t…

    Stage

    Not phased

    Ages

    12 to 18

    Site

    Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT06159127 on ClinicalTrials.gov

22. Acoustic Waveform Respiratory Evaluation

    The study will evaluate the feasibility of using smartphone speakers and microphones to evaluate the caliber of the airways, detect airway obstruction, aid in airway disease diagnosis, and identify disease exacerbations.

    Stage

    Not phased

    Ages

    8 to 70

    Site

    Indiana University, Indianapolis, Indiana

    Locations

    2 in total

    Run by

    Indiana University

    See if you can join NCT06512064 on ClinicalTrials.gov

23. A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

    The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compared with FF/VI after 24 weeks of treatment.

    Stage

    Phase 3

    Ages

    12 to 17

    Site

    GSK Investigational Site, Birmingham, Alabama

    Locations

    67 in total

    Run by

    GlaxoSmithKline

    See if you can join NCT05757102 on ClinicalTrials.gov

24. A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)

    This study aims to generate additional safety data on the propellant component of the reformulated product by comparing metered dose inhaler (MDIs) containing HFA-152a (test) with HFA-134a (reference).

    Stage

    Phase 3

    Ages

    18 and older

    Site

    GSK Investigational Site, Aventura, Florida

    Locations

    18 in total

    Run by

    GlaxoSmithKline

    See if you can join NCT07645248 on ClinicalTrials.gov

25. A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-2)

    The study aims to demonstrate the superiority of GSK5784283 compared to placebo in reducing the annualized rate of clinically meaningful asthma exacerbations.

    Stage

    Phase 3

    Ages

    12 to 80

    Site

    GSK Investigational Site, Miami Lakes, Florida

    Run by

    GlaxoSmithKline

    See if you can join NCT07782996 on ClinicalTrials.gov