Anxiety Clinical Trials

129 studies are recruiting for anxiety in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Animal Assisted Therapy

   This study looks at whether walking with a therapy dog helps adult and pediatric trauma patients move more during their hospital stay. Early movement after an injury or surgery can prevent problems such as blood clots, pressure sores, and muscle loss, but pain and anxiety often make it hard for pat…

   Stage

   Not phased

   Ages

   4 to 99

   Site

   University of Kentucky Albert B. Chandler Hospital, Lexington, Kentucky

   Run by

   Andrew Bernard

   See if you can join NCT07227181 on ClinicalTrials.gov

2. Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors

   Conditions treated in intensive care units (ICUs) such as the acute respiratory distress syndrome (ARDS), congestive heart failure, COVID pneumonia, and sepsis are common. These can lead to high rates of depression, anxiety, and PTSD that worsen quality of life. Yet there are few effective strategi…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Duke University Medical Center, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT06538246 on ClinicalTrials.gov

3. A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

   The goal of this study is to learn how psychedelics may help symptoms of depression and anxiety. Participants with major depressive disorder experiencing symptoms of depression and anxiety will receive one dose of either a drug related to psilocybin or a placebo. Assessments include interviews, sel…

   Stage

   Phase 2

   Ages

   21 to 65

   Site

   The Ohio State University Department of Psychiatry, Columbus, Ohio

   Run by

   Ohio State University

   See if you can join NCT06820723 on ClinicalTrials.gov

4. The Effects of Audio-Based Therapy on Anxiety in Psoriasis

   Anxiety in psoriasis is associated with impaired quality of life, and the prevalence of anxiety symptoms in psoriatic populations is approximately 34% and anxiety disorders up to 16%. Many experts recommend routine screening, referral, and interventions for anxiety in psoriasis; however, many barri…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Liao Lab at UCSF, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT07390487 on ClinicalTrials.gov

5. AROMA-NT: Essential Oils and Wearable TENS Device for Chronic Nausea

   This study will investigate how two inhaled essential oil products (QueaseEASE and STILL) and a wearable transcutaneous electrical nerve stimulation (TENS) device (ReliefBand) affect chronic nausea and anxiety in adults with longstanding nausea. The goal is to better understand the mechanisms by wh…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Ohio State University Wexner Medical Center, Columbus, Ohio

   Run by

   Ohio State University

   See if you can join NCT07720336 on ClinicalTrials.gov

6. Virtual Poetry Workshops to Enhance Patient Well Being and Reduce Anxiety

   This study examines whether participating in poetry workshops can improve emotional well-being among patients with chronic digestive symptoms. Many individuals with long-standing digestive conditions experience distress, anxiety, isolation, and difficulty expressing their emotions in clinical setti…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Ohio State University Wexner Medical Center, Columbus, Ohio

   Run by

   Ohio State University

   See if you can join NCT07717541 on ClinicalTrials.gov

7. Intraoperative Music Therapy in TAVR Patients

   The purpose of this study is to evaluate the effect of intraoperative music on patient anxiety and comfort during transcatheter aortic valve replacement (TAVR) procedures.

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Rhode Island Hospital, Providence, Rhode Island

   Run by

   Rhode Island Hospital

   See if you can join NCT07591922 on ClinicalTrials.gov

8. Temporal Interference in Psychiatry (TIP): Neuromodulation Using Temporal Interference

   This study aims to understand the neural, behavioral and clinical effects of temporal interference (TI), a type of neuromodulation method, in healthy populations and in individuals with anxiety and stress-related conditions.

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Emory University, Atlanta, Georgia

   Run by

   Emory University

   See if you can join NCT07558759 on ClinicalTrials.gov

9. Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

   The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the >30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care enga…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06557005 on ClinicalTrials.gov

10. Developing a Digital Intervention for Adolescent Nonsuicidal Self-injury

    This is a feasibility trial of a digital mental health intervention aimed at adolescents (ages 14-18) with nonsuicidal self-injury and who are not currently engaged in mental health treatment. The study has two arms: a self-guided DMHI and an active control which will involve the delivery of non-in…

    Stage

    Not phased

    Ages

    14 to 18

    Site

    Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT07224165 on ClinicalTrials.gov

11. Phase II: Engagement and Clinical Impact of the Teleo Virtual Therapy Platform in Clinical Settings

    This Phase II trial will examine engagement in telehealth for children undergoing psychotherapy. Specifically, the trial will examine patient engagement in Teleo, a virtual therapy platform specifically designed for psychotherapy with youth, as compared to standard video conferencing.

    Stage

    Not phased

    Ages

    5 to 14

    Site

    Stanford University, Stanford, California

    Locations

    2 in total

    Run by

    Stanford University

    See if you can join NCT07155707 on ClinicalTrials.gov

12. FlowMD Feasibility Study

    The goal of this clinical trial is to learn if the FlowMD mobile app is feasible to be used to manage mild anxiety in adults. It will also learn if the app is effective at managing anxiety in adults. Participants will: Use the FlowMD app daily to complete a 1-5 minute guided breathwork session over…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Helfgott Research Institute, Portland, Oregon

    Run by

    National University of Natural Medicine

    See if you can join NCT07672925 on ClinicalTrials.gov

13. Recovery Through Inspiration, Support, and Empowerment

    The goal of this pilot study is to test the effectiveness of a novel intervention for young adults (ages 18-27) with mental health conditions who have been released from an acute care psychiatric facility. The intervention aims to reduce suicidality, depression, anxiety, re-hospitalization, and imp…

    Stage

    Not phased

    Ages

    18 to 27

    Site

    The University of Texas Southwestern Medical Center, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT07051200 on ClinicalTrials.gov

14. Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

    A growing number of patients are surviving a stay in the intensive care unit (ICU) but may experience long-lasting psychological problems, but research evaluating such treatment for ICU patients is scant. The goal of this pilot randomized controlled trial is to evaluate the feasibility, acceptabili…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Johns Hopkins Hospital, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT06341972 on ClinicalTrials.gov

15. Therapy Dog Visits for Patients Hospitalized With Traumatic Injuries

    Animal assisted therapy (AAT) with dogs has been shown to be beneficial for a wide range of patients with both acute and chronic illnesses, including spinal cord injuries, heart failure, myocardial infarctions, strokes, cancer, post-traumatic stress disorder, and depression. Studies have also demon…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Boston Medical Center, Trauma Inpatient Service, Boston, Massachusetts

    Run by

    Boston Medical Center

    See if you can join NCT06812247 on ClinicalTrials.gov

16. Behavioral Exposure for Introceptive Tolerance RCT

    Behavioral Exposure for Interoceptive Tolerance (BE-FIT) is a mechanism-informed behavioral intervention to target exercise anxiety. The three primary components of BE-FIT include: (1) exposure to feared bodily sensations and exercise; (2) prevention of safety behavior use before/during/after exerc…

    Stage

    Not phased

    Ages

    40 and older

    Site

    RWJ Cardiac Rehab at East Brunswick, East Brunswick, New Jersey

    Locations

    3 in total

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT05398276 on ClinicalTrials.gov

17. Animal Assisted Therapy in Pediatric Dentistry

    A prospective randomized trial measuring physiologic biometrics and perceptions of stress during a pediatric dental exam, cleaning, and simulated radiographs with or without a therapy dog present.

    Stage

    Not phased

    Ages

    4 to 8

    Site

    General & Oral Health Center, Chapel Hill, North Carolina

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT05464888 on ClinicalTrials.gov

18. Process-Based Approach Case Series For Anxiety Problems

    A case series of PBA intervention for anxiety problems.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham Dr. Borgogna's lab, Birmingham, Alabama

    Run by

    University of Alabama at Birmingham

    See if you can join NCT07352592 on ClinicalTrials.gov

19. Cannabidiol and Older Adult Cannabis Users

    Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use …

    Stage

    Phase 2

    Ages

    60 and older

    Site

    University of Colorado at Boulder, Boulder, Colorado

    Run by

    University of Colorado, Boulder

    See if you can join NCT06290063 on ClinicalTrials.gov

20. Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4

    This study seeks to understand emotion regulation in those with young adults with anxiety using real-time functional magnetic resonance imaging neurofeedback, a tool that allows individuals to control brain activity. The goal of this project is to understand how receiving feedback about one's own b…

    Stage

    Not phased

    Ages

    18 to 24

    Site

    University of Michigan, Ann Arbor, Michigan

    Run by

    University of Michigan

    See if you can join NCT06563310 on ClinicalTrials.gov

21. RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty

    It is envisioned that multipronged benefits from this pilot work for the UPMC ISD and its members. It is expected the RxWell platform to provide the following benefits: expansion of the use of RxWell to all UPMC ISD members providing peri-operative mood management with advantage of improved peri-op…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    UPMC East, Monroeville, Pennsylvania

    Locations

    3 in total

    Run by

    University of Pittsburgh

    See if you can join NCT05658796 on ClinicalTrials.gov

22. My Wellbeing Guide: A Novel Tool for Managing Stress and Improving Quality of Life

    The purpose of this study is to examine the implementation and effectiveness of the psychosocial eHealth intervention, My Wellbeing Guide, on the proposed primary outcome, depressive symptoms, in patients diagnosed with cancer who receive care at Northwestern Medicine and the University of Miami He…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT05369429 on ClinicalTrials.gov

23. Exploring Virtual Reality Adventure Training Exergaming

    The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans. A randomized controlled trial using a repeated measure design with a 1-month follow-up assessment will be employed to examine effects on physical …

    Stage

    Not phased

    Ages

    18 to 45

    Site

    University of Texas at Arlington, Arlington, Texas

    Run by

    The University of Texas at Arlington

    See if you can join NCT05563805 on ClinicalTrials.gov

24. Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

    The study will examine the role of digital wellness modules (brief mindfulness and light to moderate physical exercise) delivered through a smartphone wellness application and their short-term effects on health behavior motivation and change, and longer-term quality of life and non-pathological aff…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Yale University, New Haven, Connecticut

    Run by

    Yale University

    See if you can join NCT05810259 on ClinicalTrials.gov

25. Telehealth Collaborative Care Model (CoCM) in Lung Cancer

    The goal of this trial is to compare the impact of two outreach strategies (high touch vs. standard outreach) on a collaborative care program delivered via telehealth to patients with lung cancer.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    Abramson Cancer Center at Penn Medicine

    See if you can join NCT07102147 on ClinicalTrials.gov