Anxiety Clinical Trials

129 studies are recruiting for anxiety in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Video Game Play to Alleviate Adolescent Anxiety

   Adolescence is a critical period for the onset and maintenance of anxiety disorders, which raises the importance of intervening early; one possibility of doing so is via digital interventions. At least two lines of research have been explored in the past years in this area. First, studies have test…

   Stage

   Not phased

   Ages

   11 to 15

   Site

   Center for Children and Families, Miami, Florida

   Locations

   3 in total

   Run by

   School of Health Sciences Geneva

   See if you can join NCT05923944 on ClinicalTrials.gov

2. Impact of Art Therapy on Self-Reported Pain and Anxiety Scores of Patients Waiting to Be Seen in the Emergency Department

   The objective of this research is to assess the effects of engaging in coloring activities on patients' self-reported pain and anxiety scores while they wait to be seen by a physician in an emergency department (ED). The current literature on patient visits in the ED highlights the significance of …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Stony Brook University Hospital, Stony Brook, New York

   Run by

   Stony Brook University

   See if you can join NCT05540106 on ClinicalTrials.gov

3. Confirmatory Efficacy of the Building a Strong Identity and Coping Skills Program

   The goal of this clinical trial is to the efficacy of the Building a Strong Identity and Coping Skills intervention within a sample of low-income and minoritized youth aged 11-14 who are seeking mental health treatment and have been placed on a waitlist to receive services. The aims of this study a…

   Stage

   Not phased

   Ages

   11 and older

   Site

   Penn State Health Medical Group - Psychiatry and Behavioral Health, Hershey, Pennsylvania

   Locations

   5 in total

   Run by

   Penn State University

   See if you can join NCT05789446 on ClinicalTrials.gov

4. Buspirone for Anxiety in Autistic Youth

   The purpose of the study is to do a preliminary trial to determine if buspirone is effective, safe, and tolerable in autistic youth with anxiety.

   Stage

   Phase 4

   Ages

   7 to 17

   Site

   Lurie Center, Lexington, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT07439042 on ClinicalTrials.gov

5. An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

   The goal of this feasibility randomized controlled trial is to assess the feasibility, acceptability, and demand, as well as preliminary effects of an evidence-based Intuitive Eating (IE) intervention among pregnant women who have obesity. The main research questions are: RQ1: What is the feasibili…

   Stage

   Not phased

   Ages

   18 and older

   Site

   San Diego State University, San Diego, California

   Locations

   2 in total

   Run by

   San Diego State University

   See if you can join NCT07792837 on ClinicalTrials.gov

6. Efficacy of a Multi-level School Intervention for LGBTQ Youth

   Efficacy of a Multi-level School Intervention for LGBTQ Youth

   Stage

   Not phased

   Ages

   12 to 20

   Site

   Washington University in St. Louis, St Louis, Missouri

   Locations

   23 in total

   Run by

   Washington University School of Medicine

   See if you can join NCT05541406 on ClinicalTrials.gov

7. Decoding and Modulating Affective Brain States

   The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS). First, the investigators will use functional Magnetic Resonance Imaging (fMRI) data to gener…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT05437705 on ClinicalTrials.gov

8. Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

   Purpose: The purpose of this research is to pilot test a novel, alternative, potentially sustainable system of teacher-delivered, task-shifted child mental health care. Participants: ~300 estimated Procedures: This is a RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) guided, mi…

   Stage

   Not phased

   Ages

   5 to 99

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT06587230 on ClinicalTrials.gov

9. Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story

   The main goal of this research is to help families who are experiencing food insecurity (FI) and help mothers with depression. The next goal is to provide other resources to help with household needs like rent or utility assistance, health insurance, anxiety, and depression. Our theory is that help…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Texas Children's Hospital, Houston, Texas

   Run by

   Baylor College of Medicine

   See if you can join NCT05809115 on ClinicalTrials.gov

10. Evaluating Buspirone to Treat Opioid Withdrawal

    The investigators propose a rigorous, Phase II, three-group, placebo-controlled double-blind randomized controlled trial (RCT) to evaluate the efficacy of buspirone for both withdrawal and craving among individuals with opioid use disorder (OUD) undergoing a standardized stepwise taper. During this…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    Kahlert Institute for Addictino Medicin, Baltimore, Maryland

    Run by

    University of Maryland, Baltimore

    See if you can join NCT05511909 on ClinicalTrials.gov

11. Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester Abortions

    This single center, double blind, randomized controlled trial will evaluate whether adding intravenous diphenhydramine to a standard moderate sedation regimen improves pain control during first trimester procedural abortion. Participants undergoing uterine aspiration at less than 13 weeks gestation…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Gender Wellness OB/GYN, Rochester, New York

    Run by

    University of Rochester

    See if you can join NCT07542730 on ClinicalTrials.gov

12. AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study

    The purpose of this research is to investigate the feasibility, acceptability, appropriateness, and preliminary efficacy of a wearable and artificial intelligence-driven mobile application-based exercise prescription grounded in self-determination theory (SDT) and behavioral change techniques (BCTs…

    Stage

    Not phased

    Ages

    65 and older

    Site

    Kinesiology, Recreation, and Sport Studies (865) 974-3340 krss@utk.edu, Knoxville, Tennessee

    Run by

    The University of Tennessee, Knoxville

    See if you can join NCT07768670 on ClinicalTrials.gov

13. Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

    The VA wants to understand what type of integrative and whole health approaches are helpful for Veterans. The study is comparing two primary care based mental health treatments, a mindfulness class that teaches mindfulness meditation and a problem-solving class that teaches problem-solving skills a…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona

    Locations

    4 in total

    Run by

    VA Office of Research and Development

    See if you can join NCT06162741 on ClinicalTrials.gov

14. Anxiety Skills Study

    The purposes of this study are: (1) to identify baseline predictors of relative success in cognitive, behavioral, and mindfulness-based treatments for anxiety, (2) explore who benefits from a brief, video-based skill training compared to receiving 4 sessions of therapy, and (3) to evaluate how dura…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Psychology Building at Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT07774481 on ClinicalTrials.gov

15. Healing Hearts of Hospitalized Patients

    The study aims to evaluate the impact of a bedside-delivered virtual reality (VR) mindfulness experience on well-being and psychosocial outcomes among hospitalized adult patients compared to standard of care (SOC; no added mindfulness intervention).

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Stanford Health Care (SHC), Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT06935604 on ClinicalTrials.gov

16. Grow With Grit: A School Nurse-Led SBIRT Pilot for Early Anxiety Detection

    All enrolled students and their parents or guardians will complete baseline anxiety questionnaires. Students with a positive baseline screen will receive a brief school nurse-delivered coping skill, referral support when indicated, and follow-up assessments at approximately three and six months. St…

    Stage

    Not phased

    Ages

    8 to 12

    Site

    West Elementary School, Great Falls, Montana

    Locations

    4 in total

    Run by

    McLaughlin Research Institute for Biomedical Sciences, Inc.

    See if you can join NCT07766785 on ClinicalTrials.gov

17. Psilocybin-Assisted Therapy for Intergenerational Trauma

    This is an open-label psilocybin-assisted therapy study that will examine the safety and tolerability of psilocybin-assisted therapy in the offspring of genocide survivors with mood and anxiety disorders. The study will also investigate the efficacy of psilocybin-assisted therapy in reducing sympto…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    The Parsons Research Center for Psychedelic Healing, New York, New York

    Run by

    Rachel Yehuda

    See if you can join NCT06899165 on ClinicalTrials.gov

18. Sleep, Dreaming, and Virtual Reality for Mental Health

    People spend approximately one-third of their lives asleep, yet sleep is often underused as an opportunity to support psychological well-being. Contemplative traditions, including Tibetan Dream Yoga, have developed practices that use waking imagination and lucid dreaming to explore perception, awar…

    Stage

    EARLY_Phase 1

    Ages

    18 and older

    Site

    Northwestern University, Evanston, Illinois

    Locations

    2 in total

    Run by

    Northwestern University

    See if you can join NCT07408206 on ClinicalTrials.gov

19. TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors

    This clinical research study is to learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy for cancer survivors with depression and/or anxiety.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    The University of Texas M. D. Anderson Cancer Center, Houston, Texas

    Run by

    M.D. Anderson Cancer Center

    See if you can join NCT06801041 on ClinicalTrials.gov

20. Non-invasive Cranial Electrical Stimulation for Mealtime Anxiety in Adults With Eating Disorders

    The study is to evaluate the feasibility of using a non-invasive brain stimulation device in a sample of inpatients with eating disorders (ED). The study will help researchers evaluate whether their device protocol is practical for eating disorder inpatients as a way to manage eating disorder and a…

    Stage

    Not phased

    Ages

    18 to 30

    Site

    Rogers Behavioral Health, Oconomowoc, Wisconsin

    Run by

    Rogers Behavioral Health

    See if you can join NCT07017322 on ClinicalTrials.gov

21. Mobile Cognitive Behavioral Therapy for Stroke

    This study aims to assess the feasibility and acceptability of "MAYA", a mobile cognitive behavioral therapy app for anxiety and mood disorders, in adults who have had a stroke.

    Stage

    Not phased

    Ages

    40 to 79

    Site

    Weill Cornell Medicine, New York, New York

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT06689878 on ClinicalTrials.gov

22. Safe & Sound Protocol in Adults With Trauma and SUD

    This study will explore whether the use of the Safe and Sound Protocol (SSP) app is an effective adjunct to treatment as usual (TAU) in individuals with co-occurring substance use disorders and trauma. This study will recruit 129 participants (100 completers) randomized to receive either active or …

    Stage

    Not phased

    Ages

    18 to 75

    Site

    Caron Treatment Centers, Wernersville, Pennsylvania

    Run by

    Caron Treatment Centers

    See if you can join NCT07219056 on ClinicalTrials.gov

23. Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.

    The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness. CBT involves teaching the patient skills to enable them to gradually come into contact with feared situa…

    Stage

    Not phased

    Ages

    5 to 18

    Site

    Bradley Hospital, East Providence, Rhode Island

    Run by

    Bradley Hospital

    See if you can join NCT06934525 on ClinicalTrials.gov

24. Developing Resilience and Anxiety Management Through the Arts

    The Developing Resilience and Anxiety Management Through the Arts (DRAMA) Study examines the degree to which the arts can help to address stress, anxiety, and sad mood in children and adolescents. The researchers will pair theatrical improvisation exercises with cognitive-behavioral therapy (CBT) t…

    Stage

    Not phased

    Ages

    8 to 17

    Site

    Case Western Reserve University, Cleveland, Ohio

    Run by

    Case Western Reserve University

    See if you can join NCT07033052 on ClinicalTrials.gov

25. Supporting Mental Health and Reducing Care Stress in Caregivers of Persons With Cardiovascular Disease

    The purpose of this study is to evaluate the preliminary efficacy, feasibility, acceptability, and barriers and facilitators to implementation of the Confident Caregiver intervention among family caregivers of persons with cardiovascular disease participating in cardiac rehabilitation. Caregivers r…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of California Davis Health System, Sacramento, California

    Run by

    University of California, Davis

    See if you can join NCT07717723 on ClinicalTrials.gov