Alcohol Use Disorder Clinical Trials in Philadelphia, Pennsylvania

7 studies are recruiting for alcohol use disorder in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)

   This clinical trial aims to test the effectiveness and safety of semaglutide, a GLP-1 receptor agonist, in treating moderate to severe alcohol use disorder (AUD) in Veterans. Participants who qualify will be randomly assigned to receive either semaglutide injections or placebo injections over a 24-…

   Stage

   Phase 3

   Ages

   18 to 80

   Site

   Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia, Pennsylvania

   Locations

   19 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT07218354 on ClinicalTrials.gov

2. A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

   The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with moderate-to-severe Alcohol Use Disorder (AUD). Participation in this study will last approximately 56 weeks.

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Penn Medicine: University of Pennsylvania Health System, Philadelphia, Pennsylvania

   Locations

   118 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07219966 on ClinicalTrials.gov

3. A Study of Brenipatide in Participants With Alcohol Use Disorder

   The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with Alcohol Use Disorder (AUD) and hazardous alcohol use. Participation in this study will last approximately 56 weeks.

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Penn Medicine: University of Pennsylvania Health System, Philadelphia, Pennsylvania

   Locations

   116 in total

   Run by

   Eli Lilly and Company

   See if you can join NCT07219953 on ClinicalTrials.gov

4. Effects of Ketogenic Diet on Alcohol Intoxication

   The research study is being conducted to better understand the effects of ketosis on brain functioning and the acute effects of alcohol. Participants will be asked to undergo ~4 weeks of ketogenic diet intervention. The study involves three lab visits: Lab 1 before starting the diet, Lab 2 after ab…

   Stage

   Not phased

   Ages

   21 to 50

   Site

   Center for Studies of Addiction, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT07602270 on ClinicalTrials.gov

5. Ketone Ester Intervention in Alcohol Use Disorder

   The purpose of this research is to study how a nutritional ketone ester may effect brain function and alcohol consumption in regular alcohol users. The study will see how the brain responds, once after drinking the ketone ester and once after drinking a "placebo", which will look and taste the same…

   Stage

   Phase 2

   Ages

   21 to 65

   Site

   University of Pennsylvania Center for Studies of Addiction, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT04616781 on ClinicalTrials.gov

6. Naltrexone in AUD Reward Drinkers

   This study is a phase IV, two-arm, randomized, double-blind, placebo-controlled study to assess whether individuals identified as primarily reward drinkers are significantly more likely to reduce heavy drinking if they receive XR-NTX than a matching placebo injection. Study subjects will receive mo…

   Stage

   Phase 4

   Ages

   18 to 65

   Site

   University of Pennsylvania Center for Studies of Addiction, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT05028062 on ClinicalTrials.gov

7. Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder

   The goal of this clinical trial is to learn the effects of ketone supplement compared to placebo on alcohol withdrawal symptoms during a 4 day alcohol withdrawal management treatment in adults with moderate to severe alcohol use disorder at the Hospital of the University of Pennsylvania, Cedar Deto…

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Center for Studies of Addiction, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT06559995 on ClinicalTrials.gov