Aging Clinical Trials in Boston, Massachusetts

11 studies are recruiting for aging in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Artificial Intelligence-Based Health Assessment From Face Photographs - Healthy Volunteer Study

   The investigators aim to examine how FaceAge estimates (a measure of biological age based on facial features) change across different time points and identify factors that may influence these changes. This will help the investigators understand the consistency and reliability of the FaceAge algorit…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Run by

   Brigham and Women's Hospital

   See if you can join NCT07719049 on ClinicalTrials.gov

2. Memory Enhancement in Aging With Optimal Dosing

   This project optimizes high-resolution transcranial Alternating Current Stimulation (tACS) to improve memory in healthy older adults, advancing drug-free approaches for Alzheimer's disease and related dementia (ADRD). We test stimulation schedules and develop an adaptive, brain-guided tACS system t…

   Stage

   Not phased

   Ages

   65 and older

   Site

   111 Cummington Mall, Boston, Massachusetts

   Run by

   Boston University Charles River Campus

   See if you can join NCT07461584 on ClinicalTrials.gov

3. Restructuring the Alpha-Gamma Code in Aging Vision

   Tests whether age-related visual deficits arise from disrupted alpha-gamma coupling in visual cortex (V1) and MT. Uses fMRI, source-resolved HD-EEG, and personalized complex-waveform HD-tACS to (1) quantify aging effects on phase-amplitude coupling, (2) drive PAC into a preferred "gamma-at-alpha-tr…

   Stage

   EARLY_Phase 1

   Ages

   18 and older

   Site

   111 Cummington Mall, Boston University, Boston, Massachusetts

   Run by

   Boston University Charles River Campus

   See if you can join NCT07208318 on ClinicalTrials.gov

4. Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait

   The goal of this intervention study is to determine if a new electronic stimulation device, similar to a TENS can improve balance and make walking easier in older individuals with reduced balance function. The main question aims to answer the following: Can using the device improve walking speed in…

   Stage

   Not phased

   Ages

   21 and older

   Site

   Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Massachusetts Eye and Ear Infirmary

   See if you can join NCT06688578 on ClinicalTrials.gov

5. Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

   People with HIV experience earlier impairments in physical function compared to people in the general population. They also exhibit an earlier presentation and more rapid development of frailty, a multisystemic syndrome of aging characterized by reduced activity, fatigue, slowness, weakness, and we…

   Stage

   Phase 2

   Ages

   50 to 80

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Massachusetts General Hospital

   See if you can join NCT06554717 on ClinicalTrials.gov

6. Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2

   This study consists of three aims focused on examining the feasibility of adding the Geriatric Resources and Assessment for the Care of Elders (GRACE) model to structured Annual Wellness Visits (AWVs) to improve patient and caregiver outcomes and reduce hospitalizations in older adults with complex…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mass General Brigham, Boston, Massachusetts

   Locations

   4 in total

   Run by

   Massachusetts General Hospital

   See if you can join NCT07166861 on ClinicalTrials.gov

7. The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults

   To critically examine biological, clinical, and behavioral modulators of progressive resistance training-associated exercise response heterogeneity in physical function and whole-body metabolism in older adults.

   Stage

   Not phased

   Ages

   65 and older

   Site

   Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Mayo Clinic

   See if you can join NCT06940037 on ClinicalTrials.gov

8. Apple Health Study

   The Apple Health Study aims to build a diverse and inclusive group of participants to help researchers advance our understanding of how signals and information collected from apps and devices relate to health and may be used to predict, detect, monitor, and manage changes in health. To enroll, US r…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Apple Inc.

   See if you can join NCT06958523 on ClinicalTrials.gov

9. Multimodal Musical Stimulation for Healthy Neurocognitive Aging

   This is a Stage I randomized, sham-controlled trial on the effects of multimodal musical stimulation on working memory in aging. Neurologically healthy older and younger adults will be tested on working memory and electroencephalography in the first randomized controlled trial of music as a form of…

   Stage

   Not phased

   Ages

   18 to 95

   Site

   Northeastern University, Boston, Massachusetts

   Run by

   Northeastern University

   See if you can join NCT06229093 on ClinicalTrials.gov

10. Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

    The aim of this study is to design a sleep and mindfulness intervention to improve sleep, quality of life, and cognitive function among older adults.

    Stage

    Not phased

    Ages

    55 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT06989619 on ClinicalTrials.gov

11. Mindfulness for Cognition in Early-stage Alzheimer's Disease

    The goal of this clinical trial is to learn if mindfulness meditation can improve outcomes in older adults with and without cognitive impairment. The main questions it aims to answer are: 1. How does mindfulness impact thinking and memory? 2. How does mindfulness influence brain function and struct…

    Stage

    Not phased

    Ages

    50 to 100

    Site

    VA Boston Healthcare System - Jamaica Plain Campus, Boston, Massachusetts

    Run by

    VA Boston Healthcare System

    See if you can join NCT06792877 on ClinicalTrials.gov