Acute Kidney Injury Clinical Trials

35 studies are recruiting for acute kidney injury in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 2

1. Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

   This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major adverse kidney events in in patients with congestive heart failure under…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh, Pennsylvania

   Locations

   3 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT04982419 on ClinicalTrials.gov

2. Nafamostat Efficacy in Phase 3 Registrational CRRT Study

   A prospective, randomized, placebo-controlled clinical study to investigate the safety and efficacy of Niyad (nafamostat mesylate) for anticoagulation of extracorporeal blood circulating through a dialysis filter in patients undergoing CRRT who cannot tolerate heparin or are at higher risk for blee…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   University of California Los Angeles, Los Angeles, California

   Locations

   10 in total

   Run by

   Talphera, Inc

   See if you can join NCT06150742 on ClinicalTrials.gov

3. Cystatin and Early AKI Detection Contrast Induced Acute Kidney Injury

   To determine the clinical utility of serum cystatin C in early detection of acute kidney injury (AKI).

   Stage

   Not phased

   Ages

   18 and older

   Site

   Morton Plant Hospital, Clearwater, Florida

   Locations

   4 in total

   Run by

   BayCare Health System

   See if you can join NCT07197957 on ClinicalTrials.gov

4. The Biosonographic Index

   In this exploratory study we explore the use of Shear Wave Elastography to differentiate between Acute Kidney Injury after vascular surgery and among the healthy population.

   Stage

   Not phased

   Ages

   19 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT04144894 on ClinicalTrials.gov

5. Combining Biomarkers and Electronic Risk Scores to Predict AKI in Hospitalized Patients

   The study's objective is to evaluate the additive value of renal biomarkers (from blood and urine) for identifying individuals at high risk for severe acute kidney injury (AKI) above that of a novel natural language processing (NLP)-based AKI risk algorithm. The risk algorithm is based on electroni…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Chicago Medical Center, Chicago, Illinois

   Locations

   2 in total

   Run by

   University of Chicago

   See if you can join NCT05988658 on ClinicalTrials.gov

6. Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

   The objective is to determine the effectiveness of pulsatile flow during cardiopulmonary bypass to reduce the incidence of acute kidney injury after cardiac surgery. Investigators will also evaluate the safety and impact of pulsatile flow on clinical outcomes compared to non-pulsatile flow during c…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   University of Colorado Hospital, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT06349577 on ClinicalTrials.gov

7. Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial)

   The central hypothesis of this research study is that perioperative administration of the proton pump inhibitor (PPI) pantoprazole could reduce the development of acute kidney injury (AKI) following cardiac surgery by activation molecular pathways for kidney protection. The investigators propose a …

   Stage

   Phase 2

   Ages

   18 to 90

   Site

   Memorial Hermann Texas Medical Center, Houston, Texas

   Run by

   The University of Texas Health Science Center, Houston

   See if you can join NCT06706258 on ClinicalTrials.gov

8. NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

   A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Kaiser Permanente San Francisco Medical Center, San Francisco, California

   Run by

   Kaiser Permanente

   See if you can join NCT04750616 on ClinicalTrials.gov

9. Optimizing Pulsatility During Cardiopulmonary Bypass

   Cardiopulmonary bypass during cardiac surgery provides blood flow to the body during surgery but has adverse effects on different organs. Blood flow during cardiopulmonary bypass may be pulsatile or non-pulsatile, which may impact normal organ function after surgery. The study will collect data on …

   Stage

   Not phased

   Ages

   50 to 70

   Site

   University of Colorado Hospital, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT05344573 on ClinicalTrials.gov

10. Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry

    The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients. Physiologic data measurements will be collected from enrolled subjects using elec…

    Stage

    Not phased

    Ages

    18 and older

    Site

    George Washington University Hospital, Washington D.C., District of Columbia

    Locations

    9 in total

    Run by

    Potrero Medical

    See if you can join NCT04669548 on ClinicalTrials.gov