Wounds and Injuries Clinical Trials

15 studies are recruiting for wounds and injuries in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Research Study of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma

   Bleeding from intra-abdominal injuries is a leading cause of traumatic deaths in children. Abdominal CT is the reference standard test for diagnosing intra-abdominal injuries. Compelling reasons exist, however, to both aggressively evaluate injured children for intra-abdominal injuries with CT and …

   Stage

   Not phased

   Ages

   Up to 17

   Site

   University of California, Davis Medical Center, Sacramento, California

   Locations

   6 in total

   Run by

   University of California, Davis

   See if you can join NCT05910567 on ClinicalTrials.gov

2. Blood Flow Restriction Training After Patellar INStability

   This research study is designed to allow health care professionals and researchers to answer many questions about whether a new type of physical therapy called blood flow restriction training (called BFRT) will improve recovery for those with patellar instability.

   Stage

   Not phased

   Ages

   14 to 40

   Site

   UK Healthcare at Turfland, Lexington, Kentucky

   Locations

   4 in total

   Run by

   Caitlin Conley

   See if you can join NCT04554212 on ClinicalTrials.gov

3. Trauma Resuscitation With Low-Titer Group O Whole Blood or Products

   The goal of this clinical trial is to compare the effectiveness of unseparated whole blood (referred to as Low-Titer Group O Whole Blood) and the separate components of whole blood (including red cells, plasma, platelets, and cryoprecipitate) in critically injured patients who require large-volume …

   Stage

   Phase 3

   Ages

   15 and older

   Site

   University of Alabama at Birmingham, UAB Hospital, Birmingham, Alabama

   Locations

   13 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05638581 on ClinicalTrials.gov

4. Pilot Trial for WounDx™ Clinical Decision Support Tool

   The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experimental and not yet approved by the United States Food and Drug Administration (FDA). WounDx uses information about a patient's wound to gene…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   University of Alabama - Birmingham Hospital, Birmingham, Alabama

   Locations

   5 in total

   Run by

   Henry M. Jackson Foundation for the Advancement of Military Medicine

   See if you can join NCT06921707 on ClinicalTrials.gov

5. Human Penile Allotransplantation

   Injuries to the genitalia are of concern to the military with emphasis placed on the surgical reconstruction and psychological health of these Wounded Warriors. However, despite significant surgical advances in microvascular surgery and autologous free tissue transfer, conventional reconstructions …

   Stage

   Phase 2

   Ages

   18 to 69

   Site

   Johns Hopkins University School of Medicine, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT02395497 on ClinicalTrials.gov

6. Feasibility Study for Fibroblast Autologous Skin Grafts

   This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Johns Hopkins School of Medicine, Dermatology Department, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT01964859 on ClinicalTrials.gov

7. Human Upper Extremity Allotransplantation

   Background: Millions of people each year sustain injuries, have tumors surgically removed, or are born with defects that require complex reconstructive surgeries to repair. In the case of hand, forearm, or arm amputation, prostheses only provide less than optimal motor function and no sensory feedb…

   Stage

   Phase 2

   Ages

   18 to 69

   Site

   Johns Hopkins University School of Medicine, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT01459107 on ClinicalTrials.gov

8. Effect of Giving Reduced Fluid in Children After Trauma

   This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volu…

   Stage

   Not phased

   Ages

   0 to 15

   Site

   Columbia University Irving Medical Center NewYork-Presbyterian Morgan Stanley Children's Hospital, New York, New York

   Locations

   4 in total

   Run by

   Columbia University

   See if you can join NCT04201704 on ClinicalTrials.gov

9. Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness

   This unblinded Phase II clinical trial will test the effects of individualized acupuncture treatments offered in extant acupuncture practices in the community; practitioners will have had at least 5 years of experience plus additional training provided by the study. Veterans with diagnosed symptoms…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Various, Los Angeles, California

   Locations

   10 in total

   Run by

   University of Utah

   See if you can join NCT06716411 on ClinicalTrials.gov

10. Food is Medicine Prospective Study

    The purpose of this study is to examine the impact of a medically tailored post-operative meal delivery program on surgical outcomes and metabolic lab markers in orthopaedic trauma patients. Patients will have 12 days of meals and shakes delivered to their house through our partnership with Meals o…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cedars-Sinai Medical Center, Los Angeles, California

    Run by

    Cedars-Sinai Medical Center

    See if you can join NCT07169448 on ClinicalTrials.gov

11. 4-Aminopyridine to Treat Skin Burns

    Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin. There is a need to develop treatments to accelerate and improve healing of burn injuries. More research is needed to evaluate the role o…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Arizona, Tucson, Arizona

    Run by

    John Elfar

    See if you can join NCT06596434 on ClinicalTrials.gov

12. Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing

    This study is being performed to assess the effectiveness of Altrazeal(R) Transforming Powder Dressing (TPD) in patients with partial thickness burns compared to the current standard of care (SOC) dressing. Adult men and women 18-65 years old who are hospitalized with an acute (meaning the burn inj…

    Stage

    Phase 4

    Ages

    18 to 65

    Site

    University of California-Irvine, Orange, California

    Locations

    6 in total

    Run by

    ULURU Inc.

    See if you can join NCT05424354 on ClinicalTrials.gov

13. 4-aminopyridine for Skin Wound Healing

    Many patients suffer from chronic non-healing wounds as well as acute wounds. There is a need to develop treatments to accelerate and improve healing of chronic and acute wounds. More research is needed to evaluate the role of 4-aminopyridine (4-AP), a promising new agent with an excellent safety p…

    Stage

    Phase 2

    Ages

    18 to 70

    Site

    University of Arizona, Tucson, Arizona

    Run by

    John Elfar

    See if you can join NCT06333171 on ClinicalTrials.gov

14. APPRAISE 2.0: Live Trial of the APPRAISE Trauma Decision Support System

    This is a pilot evaluation of the APPRAISE trauma decision-support software system ("the System"). The specific objections are as follows: 1. Evaluate the robustness of the System (i.e., whether the software performs in real-time in accordance with a priori technical specifications during real-time…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Andrew Tomas Reisner

    See if you can join NCT06121661 on ClinicalTrials.gov

15. Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

    This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunct…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    North Florida/South Georgia Veterans Health System, Gainesville, Florida

    Locations

    2 in total

    Run by

    North Florida Foundation for Research and Education

    See if you can join NCT04460872 on ClinicalTrials.gov