Type 2 Diabetes Mellitus (T2DM) Clinical Trials

18 studies are recruiting for type 2 diabetes mellitus (t2dm) in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

By city

Studies now recruiting

1. A Study to Evaluate ALN-4324 on Insulin Sensitivity in Adults With Type 2 Diabetes Mellitus

   The purpose of this study is to evaluate the effect of a single dose of ALN-4324 on whole-body insulin sensitivity in participants with T2DM

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Clinical Trial Site, Chula Vista, California

   Run by

   Alnylam Pharmaceuticals

   See if you can join NCT07465224 on ClinicalTrials.gov

2. Integrating New Skills Into Diabetes Education With CGM

   This study is designed to test the preliminary efficacy of a three-stage continuous glucose monitor (CGM) integration program for older adults who are taking insulin. This study will learn if a three-stage CGM integration program ("intervention") that includes sessions focused on CGM technology ski…

   Stage

   Not phased

   Ages

   65 and older

   Site

   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT07463209 on ClinicalTrials.gov

3. The GRoceries Aimed at Increasing Nutrition Study

   Only 2% of Americans meet the recommended levels of whole grain consumption, despite its association with reduced risk of type 2 diabetes. This study aims to assess if consumers with prediabetes or type 2 diabetes can be encouraged to switch from buying refined grain products to whole grain product…

   Stage

   Not phased

   Ages

   45 to 70

   Site

   University of Pennsylvania, Philadelphia, Pennsylvania

   Run by

   University of Pennsylvania

   See if you can join NCT07167004 on ClinicalTrials.gov

4. Human Immunodeficiency Virus (HIV) Food Insecurities

   The objectives of this study are to better understand how FI (food insecurities) contributes to the development of cardiometabolic comorbidities among PWH (People with HIV) and to test a novel bilingual FI intervention designed to reduce these comorbidities among food insecure PWH. The PI and staff…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Wake Forest Health Sciences, Winston-Salem, North Carolina

   Run by

   Wake Forest University Health Sciences

   See if you can join NCT04943861 on ClinicalTrials.gov

5. Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes

   The investigators are hoping to determine whether tailoring the diet of someone with type 2 diabetes to their ethnic group while following American Diabetes Association guidelines can make a significant difference in their blood sugar controls. Participants will be required to wear a Continuous Glu…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Stanford University, Stanford, California

   Run by

   Stanford University

   See if you can join NCT06836479 on ClinicalTrials.gov

6. Time Restricted Eating in Patients With Microalbuminuria

   This is a clinical trial to assess how time-restricted eating (TRE) may improve kidney health and filtration patients with type 2 diabetes and increased protein content in their urine. All participants will be participating in TRE in which they follow a consistent 8-10 hour eating window everyday.

   Stage

   Phase 1

   Ages

   18 to 75

   Site

   Altman Clinical and Translational Research Institute, La Jolla, California

   Run by

   University of California, San Diego

   See if you can join NCT06884059 on ClinicalTrials.gov

7. Achieving Routine Intervention and Screening for Emotional Health

   The purpose of this project is to evaluate the effectiveness of diabetes distress screening and intervention on patients with type 2 diabetes mellitus (T2DM).

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Chicago, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT06887049 on ClinicalTrials.gov

8. CGM for Management of Type 2 Diabetes in Pregnancy

   The goal of this clinical trial is to learn if continuous glucose monitoring works better than self-monitoring of blood glucose (fingersticks) to treat type 2 diabetes in pregnancy. It will also learn about all risk factors (biologic, personal, social) for maternal and infant complications in type …

   Stage

   Not phased

   Ages

   18 to 50

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   7 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06628453 on ClinicalTrials.gov

9. Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

   IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Alabama, Birmingham, Alabama

   Locations

   7 in total

   Run by

   Duke University

   See if you can join NCT06906627 on ClinicalTrials.gov

10. Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

    IRIS-CKD is a two-program implementation study to improve guideline-recommended screening and treatment of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama, Birmingham, Alabama

    Locations

    7 in total

    Run by

    Duke University

    See if you can join NCT06906640 on ClinicalTrials.gov

11. Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes

    People with high blood pressure and diabetes often have low levels of key nutrients as a result of not eating enough fresh fruits and vegetables. Research studies suggest that these nutrients can lower blood pressure and blood sugar. This study will investigate if providing encouragement to adopt t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Johns Hopkins ProHealth Clinical Research Unit, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT06921356 on ClinicalTrials.gov

12. Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge

    This study aims to improve patient awareness of the utility of continuous glucose monitoring systems in blood glucose monitoring and to improve patient satisfaction regarding diabetes care, particularly in the matter of blood glucose monitoring, at the transitions of care from the inpatient setting…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Vanderbilt University Medical Center, Nashville, Tennessee

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT06852950 on ClinicalTrials.gov

13. Continuous Glucose Monitoring for Self-Management of Type 2 Diabetes in Young Adults

    Type 2 diabetes in increasing common in young adults. Utilizing a mixed-methods, community-based approach, this study offers continuous glucose monitors (CGMs) to young adults with type 2 diabetes for 30 days, and collects both quantitative and qualitative data to understand barriers and facilitato…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Scripps Health, San Diego, California

    Run by

    San Diego State University

    See if you can join NCT07065721 on ClinicalTrials.gov

14. CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes

    The purpose of this study is to compare patient adherence to blood sugar monitoring during pregnancy using two different measurement methods in pregnancies complicated by pregestational type 2 diabetes (T2DM). Pregnant patients with T2DM are at risk of having larger babies, babies with low sugar le…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Jefferson Health New Jersey, Sewell, New Jersey

    Locations

    2 in total

    Run by

    Thomas Jefferson University

    See if you can join NCT07184775 on ClinicalTrials.gov

15. Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.

    DOVE-MET-COME-100 is a single site prescreening survey study designed to identify adults who may be eligible for future industry-sponsored clinical trials. A physician will oversee the informed consent process, after which participants will be surveyed on demographics, medical history, current heal…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Clindove Research LLC, Brooklyn, New York

    Run by

    Clindove Research LLC

    See if you can join NCT07106879 on ClinicalTrials.gov

16. Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.

    The goal of this investigational study is to evaluate the safety and clinical performance of Tropocells Autologous Platelet-rich Fibrin (PRF) for wound care for both males and females, ages 18-80 years old, with Grade 1 and 2, mild to moderate, neuroischemic diabetic chronic foot ulcers in subjects…

    Stage

    Phase 2

    Ages

    18 to 80

    Site

    WoundCentrics Wound Care & Hyperbarics -Corpus Christi - Shoreline, Corpus Christi, Texas

    Locations

    2 in total

    Run by

    Estar Medical dba Medical Technologies, LTD

    See if you can join NCT06810726 on ClinicalTrials.gov

17. Low-Dose Pioglitazone in Patients With NASH (AIM 2)

    To determine the safety and efficacy of low-dose pioglitazone (15 mg per day) on liver histology in in patients with T2DM with biopsy-proven nonalcoholic steatohepatitis (NASH).

    Stage

    Phase 2

    Ages

    21 to 75

    Site

    University of Florida, Gainesville, Florida

    Run by

    University of Florida

    See if you can join NCT04501406 on ClinicalTrials.gov

18. RCT Glargine vs NPH for Treatment of DM in Pregnancy

    We are asking you to take part in this research study because you are diagnosed with pregestational Type 2 Diabetes Mellitus or Gestational Diabetes Mellitus requiring insulin therapy in pregnancy. Currently, many hospitals differ among use of insulin for management of DM in pregnancy, with NPH, gl…

    Stage

    Phase 3

    Ages

    18 and older

    Site

    Loyola University Medical Center, Maywood, Illinois

    Run by

    Loyola University

    See if you can join NCT06619301 on ClinicalTrials.gov