Suicide, Attempted Clinical Trials

17 studies are recruiting for suicide, attempted in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Pilot Study of Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts

   The goal of this clinical trial is to test an enhanced outreach intervention (EOI) delivered by Samaritans of Boston (a community organization that provides support during mental health crises) for people after they leave an emergency department (ED) visit for suicidal thoughts. The main questions …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT05825820 on ClinicalTrials.gov

2. Ketamine Treatment of Youth Suicide Attempters

   Ketamine, an NMDA antagonist, has been shown to have rapid anti- suicidal effects. However, its safety and efficacy and special populations has not been investigated and documented. Several reports in adults suggest rapid decrease of suicidal ideation. In the last decade there is an alarming increa…

   Stage

   Phase 3

   Ages

   14 to 30

   Site

   The Cleveland Clinic, Cleveland, Ohio

   Run by

   Tatiana Falcone, MD

   See if you can join NCT04763343 on ClinicalTrials.gov

3. Improving Coping to Reduce Suicide Risk Following ED Discharge

   The researchers hope to learn whether an electronic safety plan (ESP) and a supportive text messaging program are feasible and acceptable to adult patients with recent suicidal thoughts or behavior after emergency department (ED) discharge. From this study, the researchers also hope to learn how to…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   University of Michigan, Ann Arbor, Michigan

   Run by

   University of Michigan

   See if you can join NCT06614946 on ClinicalTrials.gov

4. Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

   This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future. This research is also to test the effects of standard treatment of depression on improvement in depress…

   Stage

   Not phased

   Ages

   10 to 24

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   2 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05437588 on ClinicalTrials.gov

5. A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness

   Suicide is a major public health concern, particularly among Veterans with serious mental illness (SMI, i.e., psychotic disorders or bipolar disorders). Wellness Recovery Action Plan (WRAP) is a well-established evidence-based practice for those with SMI that centers on identifying warning signs of…

   Stage

   Not phased

   Ages

   18 and older

   Site

   VA San Diego Healthcare System, San Diego, CA, San Diego, California

   Run by

   VA Office of Research and Development

   See if you can join NCT05537376 on ClinicalTrials.gov

6. Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

   The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps people prevent suicidal crises from escalating, and Interpersonal Psyc…

   Stage

   Not phased

   Ages

   12 to 24

   Site

   Johns Hopkins All Children's Hospital, St. Petersburg, Florida

   Locations

   6 in total

   Run by

   Johns Hopkins University

   See if you can join NCT06151158 on ClinicalTrials.gov

7. Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD

   The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD). Prolonged exposure (PE) and crisis response plan (CRP) have demonstrated empirical support for reducing suicide attempts as compared …

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Ohio State University, Columbus, Ohio

   Run by

   Ohio State University

   See if you can join NCT06285708 on ClinicalTrials.gov

8. Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors

   The primary aim of this project are to evaluate a comprehensive, practice-ready, and deployment-focused strategy for improving the prediction and prevention of suicide attempts among a sample of 4,000 patients presenting to an ED with a psychiatric concern. The first aim is to evaluate the effects …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT05671133 on ClinicalTrials.gov

9. Written Exposure Therapy for Suicide Prevention

   Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period. However, there is an absence of evidence-based interventions designed to be delivered on in…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Texas Health Center San Antonio, San Antonio, Texas

   Run by

   Boston University

   See if you can join NCT05878795 on ClinicalTrials.gov

10. Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior

    This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change strategies for adolescents at risk of suicidal behavior who suffer from d…

    Stage

    Not phased

    Ages

    11 to 18

    Site

    Nationwide Children's Hospital, Columbus, Ohio

    Run by

    Jeff Bridge

    See if you can join NCT05390918 on ClinicalTrials.gov

11. Randomized Clinical Trial of Re-Evaluating Suicidal Thoughts in Veterans

    Suicide prevention is a top priority for VA as all continue to seek new and inventive ways to reduce suicide rates among Veterans. Many experts agree that suicide prevention efforts could be improved by making suicide-specific interventions easier to access. The current project aims to move toward …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Southeast Louisiana Veterans Health Care System, New Orleans, LA, New Orleans, Louisiana

    Run by

    VA Office of Research and Development

    See if you can join NCT05884476 on ClinicalTrials.gov

12. WellPATH-PREVENT: A Mobile Intervention for Middle-Aged and Older Adults Hospitalized for Suicidal Ideation or Attempt

    The goal of this project is to test whether WellPATH-PREVENT (a novel, mobile psychosocial intervention) improves a specific aspect of emotion regulation, i.e., cognitive reappraisal ability, and reduces suicide risk in middle-aged and older adults (50-90 years old) who have been discharged after a…

    Stage

    Not phased

    Ages

    50 to 90

    Site

    Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine, White Plains, New York

    Locations

    2 in total

    Run by

    Weill Medical College of Cornell University

    See if you can join NCT05183230 on ClinicalTrials.gov

13. Skills to Enhance Positivity in Suicidal Youth

    This is a Hybrid Type I Effectiveness-Implementation design. Specifically, this study proposes to test the effectiveness of STEP in reducing suicidal events and ideation in 216 adolescents, admitted to inpatient psychiatric care due to suicide risk. Participants will be randomized to either STEP or…

    Stage

    Not phased

    Ages

    12 to 60

    Site

    Children's Hospital, Boston, Massachusetts

    Locations

    3 in total

    Run by

    Brown University

    See if you can join NCT04994873 on ClinicalTrials.gov

14. Stepped Approach to Reducing Risk of Suicide in Primary Care

    Suicide is the second leading cause of death among young people aged 12-17 years in the United States, yet many youth at risk for suicide are not identified or go untreated. Stepped care approaches have been shown to be effective at reducing suicide risk in clinical settings, including primary care…

    Stage

    Not phased

    Ages

    12 to 17

    Site

    AxessPointe Community Health Centers/Health Quarters, Akron, Ohio

    Locations

    15 in total

    Run by

    Cynthia Fontanella

    See if you can join NCT06018285 on ClinicalTrials.gov

15. Intensive Crisis Intervention

    The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric care.

    Stage

    Not phased

    Ages

    12 to 17

    Site

    Nationwide Children's Hospital, Columbus, Ohio

    Run by

    Jennifer Hughes

    See if you can join NCT06476886 on ClinicalTrials.gov

16. Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)

    The primary aim of this grant is to conduct pilot testing on a novel personalized mobile intervention for suicide - Mobile Application to Prevent Suicide (MAPS) - and to establish feasibility, acceptability, safety, and primary outcomes (i.e., suicidal ideation and behavior; re-hospitalization).

    Stage

    Not phased

    Ages

    18 to 26

    Site

    Butler Hospital, Providence, Rhode Island

    Run by

    Butler Hospital

    See if you can join NCT05180344 on ClinicalTrials.gov

17. Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships

    This study will evaluate the effectiveness of culturally competent psychoeducational empowerment sessions in treating suicidal African-American women who are in abusive relationships.

    Stage

    Not phased

    Ages

    18 to 64

    Site

    Grady Hospital, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT00601939 on ClinicalTrials.gov