Stroke, Ischemic Clinical Trials

19 studies are recruiting for stroke, ischemic in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. The Fourth Left Atrial Appendage Occlusion Study

   LAAOS-4 aims to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in participants with atrial fibrillation, who remain at high risk of stroke, despite receiving ongoing treatment with oral anticoagulation.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Arrhythmia Research Group, Jonesboro, Arkansas

   Locations

   150 in total

   Run by

   Hamilton Health Sciences Corporation

   See if you can join NCT05963698 on ClinicalTrials.gov

2. Effect of Visual Retraining After Stroke

   This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and brain function. The investigators will also assess the effect of intens…

   Stage

   Not phased

   Ages

   21 to 80

   Site

   University of Rochester Medical Center, Rochester, New York

   Run by

   University of Rochester

   See if you can join NCT06121219 on ClinicalTrials.gov

3. Treatment With Endovascular Intervention for STroke Patients With Existing Disability

   TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   35 in total

   Run by

   University of Cincinnati

   See if you can join NCT05911568 on ClinicalTrials.gov

4. Mechanisms of Visual Restoration After Occipital Stroke

   This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and…

   Stage

   Not phased

   Ages

   21 to 80

   Site

   University of Rochester, Rochester, New York

   Run by

   University of Rochester

   See if you can join NCT07134777 on ClinicalTrials.gov

5. Vision Loss Impact on Navigation in Virtual Reality

   The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather dat…

   Stage

   Not phased

   Ages

   21 to 75

   Site

   University of Rochester, Rochester, New York

   Run by

   University of Rochester

   See if you can join NCT06047717 on ClinicalTrials.gov

6. Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

   VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, tra…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Birmingham VA Medical Center, Birmingham, Alabama

   Locations

   45 in total

   Run by

   Yale University

   See if you can join NCT05338697 on ClinicalTrials.gov

7. Study of Circulating Monocytes in Patients With Ischemic Vascular Disease

   The purpose of this research study is to discover the functions of circulating white blood cells, called monocytes, and associated circulating substances in heart attack and ischemic stroke patients. Ischemic Strokes (clots) occur as a result of an obstruction within a blood vessel supplying blood …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Connecticut Health Center, Farmington, Connecticut

   Run by

   UConn Health

   See if you can join NCT04321512 on ClinicalTrials.gov

8. Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke

   People living with the cognitive effects of stroke are at risk for recurrent stroke and further cognitive decline. Also problematic is that stroke risk clusters in families and biological family members of people who have ischemic stroke may also be at increased risk of stroke and/or cognitive decl…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of New Mexico Health Sciences Center, Albuquerque, New Mexico

   Run by

   University of New Mexico

   See if you can join NCT06479174 on ClinicalTrials.gov

9. The REACTplusNMES Trial: A Double-blinded RCT

   The aim of this study is to compare the effectiveness of 6-weeks of reactive balance training (REACT) with and without neuromuscular electrical stimulation (NMES) to paretic lower limb muscles on biomechanical, clinical, neuromuscular and neuroplastic outcomes of reactive balance control. This proj…

   Stage

   Not phased

   Ages

   18 to 90

   Site

   University of Illinois at Chicago, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT06127602 on ClinicalTrials.gov

10. Motor Recovery Through Plasticity-Inducing Cortical Stimulation

    Using the CorTec Brain Interchange (BIC) System, we will examine the effect of a plasticity-inducing therapy regime on the rehabilitation of upper limb impairment post-stroke. This study's main objective is to implement and evaluate neuroplasticity-inducing stimulation. The stimulation methods for …

    Stage

    Not phased

    Ages

    22 to 75

    Site

    University of Washington, Seattle, Washington

    Run by

    University of Washington

    See if you can join NCT06506279 on ClinicalTrials.gov

11. Promoting Recovery After STroke With Amantadine

    The investigators aim to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial (RCT). Patients will be randomized post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine arm. Patients will be on study drug or placebo f…

    Stage

    Phase 2

    Ages

    18 to 85

    Site

    The Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

    Run by

    University of Pennsylvania

    See if you can join NCT05140148 on ClinicalTrials.gov

12. NobleStitch EL STITCH Trial is a PFO Comparative Trial

    STITCH - Prospective Multi-Center Comparative Parallel Concurrent Study of the NobleStitch™ EL versus FDA-approved Amplatzer Occluder device for closure of Patent Foramen Ovale to prevent recurrent Ischemic stroke.

    Stage

    Not phased

    Ages

    18 to 60

    Site

    TMC HealthCare, Tucson, Arizona

    Locations

    2 in total

    Run by

    Nobles Medical Technologies II Inc

    See if you can join NCT04339699 on ClinicalTrials.gov

13. Utility of CC7 Transfer in Stroke Subtypes

    The purpose of this study is to evaluate the limb functional improvement after contralateral C7 root transfer in stroke patients.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Dartmouth-Health, Lebanon, New Hampshire

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT06001736 on ClinicalTrials.gov

14. DELTA (Detecting and Predicting Atrial Fibrillation in Post-Stroke Patients)

    Atrial Fibrillation (AF) is an abnormal heart rhythm. Because AF is often asymptomatic, it often remains undiagnosed in the early stages. Anticoagulant therapy greatly reduces the risks of stroke in patients diagnosed with AF. However, diagnosis of AF requires long-term ambulatory monitoring proced…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Emory Clinic, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT05795842 on ClinicalTrials.gov

15. Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia

    The goal of this clinical trial is to determine if electrical brain stimulation applied to the front parts of the brain can help people who have had a stroke improve their fatigue, language, and attention. The main question it aims to answer is: * Does transcranial direct current stimulation (tDCS)…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Syracuse University, Syracuse, New York

    Locations

    2 in total

    Run by

    Syracuse University

    See if you can join NCT07151677 on ClinicalTrials.gov

16. Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke

    Our proposed study, "NEUROBALANCE Stroke,"; aims to evaluate the effectiveness of a combined intervention involving robotic balance training and noninvasive brain stimulation in improving balance function and postural control in individuals with chronic stroke. The study will recruit 45 participant…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    Kessler Foundation, West Orange, New Jersey

    Run by

    Kessler Foundation

    See if you can join NCT07113041 on ClinicalTrials.gov

17. Transitional Care Program to Improve Risk Factors in Stroke Survivors

    The goal of this clinical trial is to evaluate whether our transitional care program helps stroke survivors better manage their risk factors for stroke to lower the risk of a repeat stroke. The main question it aims to answer is: - Does the program help participants meet the targets set by the Amer…

    Stage

    Not phased

    Ages

    30 and older

    Site

    Valley Health System, Winchester, Virginia

    Run by

    Syntrillo, Inc

    See if you can join NCT06657235 on ClinicalTrials.gov

18. Stroke Motor Rehabilitation and Recovery Study

    SMaHRT (Stroke Motor reHabiliation and Recovery sTudy) is a longitudinal study aimed at understanding the natural history of upper extremity motor recovery after ischemic and hemorrhagic stroke.

    Stage

    Not phased

    Ages

    18 to 90

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT03485040 on ClinicalTrials.gov

19. Hand and Arm Motor Recovery Via Non-invasive Electrical Spinal Cord Stimulation After Stroke

    The recovery from a stroke is often incomplete. It is the leading cause of acquired permanent disability in the adult population. Persistent functional loss of the hand and arm contributes significantly to disability. However, the current standard of care to treat hand and arm movements are inadequ…

    Stage

    Not phased

    Ages

    21 to 80

    Site

    University of Washington, Seattle, Washington

    Run by

    University of Washington

    See if you can join NCT05591196 on ClinicalTrials.gov