Stage IVB Prostate Cancer AJCC v8 Clinical Trials in Los Angeles, California

7 studies are recruiting for stage ivb prostate cancer ajcc v8 in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

   This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by bl…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Keck Medicine of USC Koreatown, Los Angeles, California

   Locations

   581 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT03866382 on ClinicalTrials.gov

2. Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

   This randomized phase III trial examines whether lengthening the dosage interval in an adaptive manner for the prostate cancer drug lutetium 177 Lu PSMA RLT improves quality of life without decreasing lifespan when compared to the standard way this medication is given. This study is for patients wi…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center, Los Angeles, California

   Locations

   129 in total

   Run by

   Alliance for Clinical Trials in Oncology

   See if you can join NCT07200830 on ClinicalTrials.gov

3. Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

   This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination with abiraterone + prednisone) added to standard of care (prostate radiation therapy and short term androgen deprivation) is more effective c…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California

   Locations

   341 in total

   Run by

   ECOG-ACRIN Cancer Research Group

   See if you can join NCT04423211 on ClinicalTrials.gov

4. Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

   This phase II trial studies how well lutetium Lu 177 dotatate works in treating patients with prostate cancer with neuroendocrine differentiation that has spread to other places in the body (metastatic). Neuroendocrine differentiation refers to cells that have traits of both hormone-producing endoc…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Los Angeles General Medical Center, Los Angeles, California

   Locations

   13 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT05691465 on ClinicalTrials.gov

5. Image-Guided Biopsies to Identify Mechanisms of Resistance in Patients With Metastatic Castration Resistant Prostate Cancer Treated With 177Lu-PSMA Radioligand Therapy

   This clinical trial studies mechanisms of resistance to 177-lutetium prostate specific membrane antigen (177Lu-PSMA) radioligand therapy using image-guided biopsies in patients with castrate-resistant prostate cancer that had spread to other places in the body (metastatic). Diagnostic procedures, s…

   Stage

   Phase 1

   Ages

   Any age

   Site

   UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California

   Run by

   Jonsson Comprehensive Cancer Center

   See if you can join NCT05398302 on ClinicalTrials.gov

6. Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial

   This phase II trial tests how well re-treatment with 177Lu-PSMA-617 works in treating patients with prostate cancer that has spread from where it first started (primary site) to other places in the body (metastatic), that continues to grow or spread after the surgical removal of the testes or medic…

   Stage

   Phase 2

   Ages

   Any age

   Site

   UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California

   Run by

   Jonsson Comprehensive Cancer Center

   See if you can join NCT06288113 on ClinicalTrials.gov

7. Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

   This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation the…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Los Angeles County-USC Medical Center, Los Angeles, California

   Locations

   338 in total

   Run by

   SWOG Cancer Research Network

   See if you can join NCT03678025 on ClinicalTrials.gov