Squamous Cell Carcinoma of Head and Neck Clinical Trials in La Jolla, California

4 studies are recruiting for squamous cell carcinoma of head and neck in La Jolla, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

   The purpose of this study is to determine safety and preliminary efficacy of amivantamab monotherapy, amivantamab in addition to pembrolizumab, amivantamab in addition to paclitaxel and amivantamab in addition to pembrolizumab and carboplatin in participants with recurrent/metastatic head and neck …

   Stage

   Phase 1

   Ages

   18 and older

   Site

   University of California at San Diego Moores Cancer Center, La Jolla, California

   Locations

   56 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT06385080 on ClinicalTrials.gov

2. A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

   This global, open-label, single arm, phase 1b study aims to learn more about whether a treatment called JNJ-90301900 is safe and effective when injected directly into tumors, along with standard chemotherapy and radiation therapy, for participants with head and neck squamous cell cancer (HNSCC; a t…

   Stage

   Phase 1

   Ages

   18 to 74

   Site

   University of California at San Diego Moores Cancer Center, La Jolla, California

   Locations

   19 in total

   Run by

   Johnson & Johnson Enterprise Innovation Inc.

   See if you can join NCT07219212 on ClinicalTrials.gov

3. A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

   The purpose of this study is to compare anti-tumor activity of amivantamab in addition to pembrolizumab and carboplatin versus pembrolizumab, 5-fluorouracil (FU), and platinum therapy (carboplatin or cisplatin) in participants with refractory/metastatic (R/M) head and neck squamous cell carcinoma (…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   Scripps Health, La Jolla, California

   Locations

   201 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT07276399 on ClinicalTrials.gov

4. Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

   The investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Moores Cancer Center UC San Diego Health, La Jolla, California

   Locations

   20 in total

   Run by

   Bicara Therapeutics

   See if you can join NCT04429542 on ClinicalTrials.gov