Spinal Cord Injuries (SCI) Clinical Trials

16 studies are recruiting for spinal cord injuries (sci) in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. mSCI: Mobile Health App for Veterans With SCI and Caregivers

   Caregivers of persons with Spinal Cord Injury (SCI) face increased risk of psychological distress, health problems, reduced quality of life, relationship strain, and restrictions in social and work participation. Military caregivers (Family Caregivers of wounded or disabled Veterans) reported simil…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT07269977 on ClinicalTrials.gov

2. Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

   The goal of this clinical trial is to evaluate the safety and preliminary efficacy of an implantable device that records and stimulates different areas of the brain to allow adults affected by disabling paralysis (see Eligibility for more details) to control and receive feedback from assistive devi…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   Johns Hopkins Medicine, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT07521930 on ClinicalTrials.gov

3. AI-Guided Predictions of Blood Pressure Dysregulation Using Perfusion Index as a Novel Biomarker in Persons With Spinal Cord Injury

   The goal of this clinical trial is to determine if perfusion index (PI) can reliably predict changes in systolic blood pressure (SBP) in persons with spinal cord injury (SCI) during a cool temperature challenge. Participants with SCI can be 18-75 years of age, male or female, neurological level of …

   Stage

   Not phased

   Ages

   18 to 75

   Site

   James J Peters VA Medical Center, The Bronx, New York

   Run by

   James J. Peters Veterans Affairs Medical Center

   See if you can join NCT07699094 on ClinicalTrials.gov

4. Dose Optimization Study of Acute Intermittent Hypoxia in Spinal Cord Injury

   This study aims to evaluate how different doses of acute intermittent hypoxia (AIH) affect lower-limb strength, reaction time, and responsiveness in individuals with spinal cord injury (SCI). The objective is to identify the dose that most effectively improves motor output while also examining para…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Shirley Ryan AbilityLab, Chicago, Illinois

   Run by

   Milap Sandhu

   See if you can join NCT07739992 on ClinicalTrials.gov

5. Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury

   The study aims to explore how cardiovascular function changes in the first year after a spinal cord injury, and to see how different treatments, like spinal stimulation through the skin (transcutaneous spinal stimulation), affect blood pressure. The main questions are: How does stimulation affect b…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   Kessler Foundation, West Orange, New Jersey

   Run by

   Kessler Foundation

   See if you can join NCT06841198 on ClinicalTrials.gov

6. Improving Heart Health in Individuals With SCI Using Home-Based Virtual Gaming

   What is the ultimate applicability of the research? Individuals with SCI face several challenges when trying to engage in exercise following injury. Barriers to engagement include cost, transportation, and lack of SCI accessible resources. At the same time, individuals with SCI are at risk of devel…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Drexel University Health Science Building, Philadelphia, Pennsylvania

   Run by

   Drexel University

   See if you can join NCT06690372 on ClinicalTrials.gov

7. Spasticity in SCI Following Acute Intermittent Hypoxia

   This study aims to observe the effects of administration of a breathing intervention (Acute Intermittent Hypoxia (AIH)) on spasticity (tightness) in individuals with incomplete Spinal Cord Injury. It is hypothesized that hypoxia will decrease the reflex threshold of the biceps brachii, indicating a…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Shirley Ryan AbilityLab, Chicago, Illinois

   Run by

   Zev Rymer

   See if you can join NCT07583498 on ClinicalTrials.gov

8. Fall Prevention Among People With Spinal Cord Injury and Multiple Sclerosis Who Use Wheelchairs and Scooters

   The research team is conducting a study to determine if a fall prevention program designed specifically for people who use wheelchairs and scooters can help people better prevent and manage falls compared to the standard of care. This study will compare two groups of participants: 1. One group will…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Disability Participation and Quality of Life (DPQOL) Laboratory, Urbana, Illinois

   Run by

   University of Illinois at Urbana-Champaign

   See if you can join NCT07167680 on ClinicalTrials.gov

9. Virtual Peer Coaching in Manual Wheelchair Skills

   The objective of this study is to determine the effectiveness of remote manual wheelchair skills training program. First, peer coaches will be enrolled and trained. Then, trainees will be enrolled into one of three interventions: intervention with remote feedback (Group 1), and a wait list control …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06295146 on ClinicalTrials.gov

10. Health Information for Persons With Spinal Cord Injury

    The goal of this pilot study is to design and feasibility test a mobile phone text messaging (SMS) self-management intervention for persons with spinal cord injury (PwSCI). The project will focus on providing a 16-week text messaging intervention on the secondary health conditions of bowel/bladder …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Washington University School of Medicine, St Louis, Missouri

    Run by

    Washington University School of Medicine

    See if you can join NCT07386522 on ClinicalTrials.gov

11. Spatiotemporal tSCS in Spinal Cord Injury

    Spinal cord injury leads to long-lasting impairment, and currently, there is no cure for paralysis. Although transcutaneous spinal cord stimulation has shown promising results in recovering lost movements, its poor selectivity in muscle recruitment compared to invasive approaches limits the type of…

    Stage

    Not phased

    Ages

    16 to 65

    Site

    Washington University, St. Louis, St Louis, Missouri

    Run by

    Washington University School of Medicine

    See if you can join NCT07397559 on ClinicalTrials.gov

12. Self-balancing Personal Exoskeleton for SCI

    This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).

    Stage

    Not phased

    Ages

    18 and older

    Site

    James J. Peters, VA Medical Center, Bronx, NY, The Bronx, New York

    Run by

    Wandercraft

    See if you can join NCT06777576 on ClinicalTrials.gov

13. Self-balancing Personal Exoskeleton for SCI (Site 2)

    This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).

    Stage

    Not phased

    Ages

    18 and older

    Site

    Kessler Foundation, West Orange, New Jersey

    Run by

    Wandercraft

    See if you can join NCT06814015 on ClinicalTrials.gov

14. Enhancing Rehabilitation Participation in Patients With SCI/D Using Motivational Interviewing

    The purpose of this multi-site clinical trial is to see whether people with spinal cord injury or disorder (SCI/D) demonstrate higher level of participation in rehabilitation sessions and other outcomes when their therapists are trained in a counseling style called motivational interviewing. We wan…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Shirley Ryan AbilityLab, Chicago, Illinois

    Locations

    3 in total

    Run by

    Shirley Ryan AbilityLab

    See if you can join NCT07364773 on ClinicalTrials.gov

15. Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation

    The goal of this clinical trial is to determine whether Lactobacillus crispatus strains isolated from the lower urinary tracts of adult women can be used as an antibiotic-sparing treatment for urinary symptoms and urinary tract infection (UTI) among adults with neurogenic lower urinary tract dysfun…

    Stage

    EARLY_Phase 1

    Ages

    18 and older

    Site

    Medstar National Rehabilitation Hospital, Washington D.C., District of Columbia

    Run by

    Medstar Health Research Institute

    See if you can join NCT07308808 on ClinicalTrials.gov

16. Hypoxia Pathways for Early Recovery After Spinal Cord Injury

    Spinal cord injury (SCI) disrupts neural pathways to respiratory motor neurons, diminishing breathing capacity and airway defense (e.g., cough). Indeed, respiratory impairment is a leading cause of infection, re-hospitalization and death after SCI. There is a critical need for new strategies to res…

    Stage

    Not phased

    Ages

    18 to 70

    Site

    Brooks Rehabilitation, Jacksonville, Florida

    Run by

    University of Florida

    See if you can join NCT07002437 on ClinicalTrials.gov