Solid Tumor Clinical Trials in New York, New York
33 studies are recruiting for solid tumor in New York, New York right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.
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Studies now recruiting
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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
BDTX-4933-101 is a first-in-human, open-label, Phase 1/2 dose escalation, dose optimization and expansion study designed to evaluate the safety and tolerability of S241656 as monotherapy and in combination with other anti-cancer therapies in participants with selected advanced malignancies. The stu…
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York, New York
- Locations
- 49 in total
- Run by
- Institut de Recherches Internationales Servier
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Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors
The purpose of this study is to find out whether the study drug, TSR-042, followed by standard chemoradiotherapy (the chemotherapy drug capecitabine + radiation therapy) and standard surgery is an effective treatment for advanced dMMR solid tumors. The study will also look at the safety of the stud…
- Stage
- Phase 2
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 10 in total
- Run by
- Memorial Sloan Kettering Cancer Center
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A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors
This is an open-label, multicenter, and nonrandomized dose escalation and dose expansion study to evaluate BGB-26808 as monotherapy or in combination with tislelizumab in participants with advanced solid tumors. The main purpose of this study is to explore the recommended dosing for BGB-26808.
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Icahn School of Medicine At Mount Sinai, New York, New York
- Locations
- 28 in total
- Run by
- BeOne Medicines
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DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer
The purpose of this study is to improve ways of providing mental health support to Spanish-speaking Latino participants who have cancer and experience depression, insomnia, and fatigue. Investigators will test a special mental health intervention called DESCANSO/REST (Depresión/Depressed Mood, Cans…
- Stage
- Not phased
- Ages
- 21 to 100
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 7 in total
- Run by
- Memorial Sloan Kettering Cancer Center
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Psychotherapy Intervention for Latinos With Advanced Cancer
The purpose of this study is to adapt a counseling intervention called Meaning Centered Psychotherapy to make it culturally relevant for Latinos. Cancer affects patients and their loved ones. Latinos often experience greater challenges due to the cancer. However, few studies and interventions focus…
- Stage
- Not phased
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 4 in total
- Run by
- Memorial Sloan Kettering Cancer Center
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Psychotherapy Intervention for Latinos With Adv Cancer
The purpose of this study is to adapt a counseling intervention called Meaning Centered Psychotherapy to make it culturally relevant for Latinos. Cancer affects patients and their loved ones. Latinos often experience greater challenges due to the cancer. However, few studies and interventions focus…
- Stage
- Not phased
- Ages
- 18 and older
- Site
- MSK at Ralph Lauren, New York, New York
- Locations
- 4 in total
- Run by
- Memorial Sloan Kettering Cancer Center
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Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
This is a Phase 1, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced, unresectable or metastatic solid tumor malignancy with homozygous deletion of the MTAP gene.
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- David H Koch, Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 25 in total
- Run by
- Bristol-Myers Squibb
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FOG-001 in Locally Advanced or Metastatic Solid Tumors
The goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial adenomatous polyposis (FAP).
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 33 in total
- Run by
- Parabilis Medicines, Inc.
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Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
GIM-531 is a first-in-class, orally bioavailable small molecule that is being developed for the treatment of advanced solid tumors as a single agent and rescue therapy. GIM-531 exhibits its primary effect through selective inhibition of regulatory T-cells (Tregs).
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Weill Cornell Medicine - New York Presbyterian Hospital, New York, New York
- Locations
- 11 in total
- Run by
- Georgiamune Inc
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A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Participants of this study will have a diagnosis of a solid tumor cancer that has come back to its original location or spread beyond its original location (advanced), came back (relapsed) or worsened (refractory) after standard treatments, or no standard treatments are available for the participan…
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
- Locations
- 7 in total
- Run by
- Memorial Sloan Kettering Cancer Center
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Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
This is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity, and effect of biomarkers of zanzalintinib administered alone, and in combination with nivolumab (doublet), nivolumab + …
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Exelixis Clinical Site #60, New York, New York
- Locations
- 122 in total
- Run by
- Exelixis
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A Study of ASP3082 in Adults With Advanced Solid Tumors
This is an open-label study. This means that people in this study and clinic staff will know that people will receive ASP3082. The study aims to check how safe and well-tolerated ASP3082 is for people with advanced solid tumors that have a specific mutation called KRAS G12D. This study will be in 2…
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Columbia University - Herbert Irving Comprehensive Cancer Center, New York, New York
- Locations
- 66 in total
- Run by
- Astellas Pharma Inc
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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
Fibroblast activation protein (FAP) is a cell surface protein that is highly expressed on the surface of cancer-associated fibroblasts (CAFs) present in the tumor microenvironment of most epithelial cancers, whereas limited expression of FAP is observed in normal tissues. In some cancers of mesench…
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Columbia University Medical Center, New York, New York
- Locations
- 41 in total
- Run by
- Novartis Pharmaceuticals
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Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors
This is a first-in-human, multicenter, open-label, dose escalation and dose expansion Phase 1/2 study to determine the MTD and/or the recommended Phase 2 dose (RP2D) and to characterize DLTs of AT-1965 as well as to investigate the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary an…
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- CBCC Global Research Site 010, New York, New York
- Locations
- 9 in total
- Run by
- Alyssum Therapeutics
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Remote Digital Physiologic Data Collection in Cancer: An MSK Registry Protocol
The purpose of this study is to develop a secure method of collecting physiologic information from patients with cancer. The researchers will use this information to learn more about how physiologic data may relate to cancer diagnosis and response to treatment, and to identify factors that may lead…
- Stage
- Not phased
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Run by
- Memorial Sloan Kettering Cancer Center
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A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
Researchers are looking for new ways to treat children with different types of melanoma (skin cancer), solid tumors, and lymphomas (blood cancers) that are any of these: * Advanced, which means cancer spread in the body or cannot be removed with surgery * Relapsed, which means cancer has come back …
- Stage
- Phase 1
- Ages
- 0 to 17
- Site
- Call for Information (Investigational Site 0031), New York, New York
- Locations
- 16 in total
- Run by
- Merck Sharp & Dohme LLC
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Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values
The purpose of this study is to translate and tailor for Latinx participants a program called Communicating with Oncology Nurses about Values from the Outset (CONVO). In CONVO, routine cancer care for each participant includes a discussion between the nurse and participant about the participant's h…
- Stage
- Not phased
- Ages
- 21 and older
- Site
- MSK at Ralph Lauren (All Protocol Activities), New York, New York
- Locations
- 5 in total
- Run by
- Memorial Sloan Kettering Cancer Center
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A Study of PYX-201 in Advanced Solid Tumors
The primary objectives of this study are to determine the recommended dose(s) of PYX-201 for participants with recurrent/metastatic (R/M) solid tumors, and to determine the objective response rate (ORR) in participants treated with PYX-201 as a single agent.
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 29 in total
- Run by
- Pyxis Oncology, Inc
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A Study of XB628 Alone and in Combination With Zanzalintinib in Participants With Recurrent Advanced or Metastatic Solid Tumors
This study consists of a Dose-Escalation stage and a Dose Expansion stage. The primary purpose of the dose escalation stage is to determine the maximum tolerated dose (MTD) and/or recommended dosage(s) for expansion (RDE[s]); and the dose expansion stage is to evaluate the preliminary antitumor act…
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Exelixis Clinical Site #7, New York, New York
- Locations
- 11 in total
- Run by
- Exelixis
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A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors
This is a Phase 1/2, open label, multiple cohort study to assess the safety and preliminary efficacy of SAR445877 as a monotherapy or in combination with other anticancer therapies for participants aged at least 18 years with advanced unresectable or metastatic solid tumors. The study will include …
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- NYU Langone Medical Center- Site Number : 8400013, New York, New York
- Locations
- 22 in total
- Run by
- Sanofi
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FORTRAS: A Study of MSK-TCR5 in People With Solid Tumor Cancers
The purpose of this study is to test the safety of MSK-TCR5 in participants with advance solid tumor cancer that has a KRAS, HRAS, or NRAS G12D mutation.
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York, New York
- Locations
- 7 in total
- Run by
- Memorial Sloan Kettering Cancer Center
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An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
The purpose of this study is to evaluate the long-term safety and the clinical benefit of pelabresib in patients with hematological and/or solid tumor indications or advanced malignancies. Additionally, participants previously enrolled in studies with pelabresib who received placebo or participants…
- Stage
- Phase 3
- Ages
- 18 and older
- Site
- New York Presbyterian Hospital, New York, New York
- Locations
- 15 in total
- Run by
- Novartis Pharmaceuticals
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A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
The primary objectives of the study are: (1) in the dose-escalation part: to evaluate safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of farletuzumab ecteribulin (MORAb-202) in participants with selected tumor types (ovarian cancer [OC], endometrial cancer [EC], non-sma…
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 58 in total
- Run by
- Eisai Inc.
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A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
Genes contain genetic code which tell the body which proteins to make. Many types of cancer are caused by changes, or mutations, in a gene called KRAS. Researchers are looking for ways to stop the actions of abnormal proteins made from the mutated KRAS gene. ASP5834 is being studied in people with …
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Memorial Sloan Kettering Cancer Center, New York, New York
- Locations
- 20 in total
- Run by
- Astellas Pharma Inc
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Brodalumab in the Treatment of Immune-Related Adverse Events
The purpose of this study is to test the safety and effectiveness of using brodalumab in patients who develop side effects from cancer immune therapy. Immune-related side effects are due to activation of the immune system in patients who previously received immunotherapy and the goal of this study …
- Stage
- Phase 1
- Ages
- 18 and older
- Site
- Columbia University Irving Medical Center, New York, New York
- Run by
- Brian Henick, MD
How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.
What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.
Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.